Intestinal flora is known to play a role in colorectal cancer metastasis via disruption of the intestinal barrier. Here, the authors discover that Escherichia coli promotes colorectal cancer liver met...

Background Genetic studies of stool frequency (SF), an indirect proxy for gastrointestinal transit, may reveal therapeutically tractable pathways relevant to IBS and other dysmotility disorders. Obje...

A covariate-aware analysis reveals that microbiome changes in the gut of patients with chronic kidney disease are better explained by intestinal transit time than by kidney function.

Cytokine receptor dimerization, induced by the binding of cytokines, can be converted into a genetically traceable fluorescent signal and engineered into reporter mouse lines to visualize processes in...

UBC researchers have engineered gut bacteria that dim their fluorescent glow in the presence of illness.

Nature Reviews Gastroenterology & Hepatology, Published online: 22 January 2026; doi:10.1038/s41575-026-01173-0Protein is an essential nutrient in the human diet. This Review explores the fate of dietary protein in the gastrointestinal tract and its influence on colonic health and disease, providing insights into dietary protein metabolism, digestion, absorption, fermentation and the implications for colonic health.

T helper 17 (TH17) cells can have both pro-tumour and antitumour effects. Understanding how they are regulated by environmental and regulatory cues according to context will inform strategies to harne...

The 2025 ISB Microbiome Symposium was a virtual scientific event hosted by the Institute for Systems Biology (ISB) on December 12, 2025. The symposium brough...

We are seeking applications from an outstanding scientist to establish and lead a new research group in human microbiome science, advancing understanding of microbe–microbe and microbe–host interactio...

You will lead delivery of a CoRE research project, managing your own research and coordinating project activities to meet deadlines. The role includes developing and adapting scientific techniques, an...