Lightnews — Scholar-powered news

Reposted by Pauline Franz

Matteo Doudin @matteodoudin.bsky.social · Apr 4

I am very happy to share that I was awarded a PhD fellowship from the Boehringer Ingelheim Fonds (BIF) for my project about nucleosome depletion in @lcbm-epfl.bsky.social with @beatfierz.bsky.social. Looking forward to joining the BIF community 😊🥳

1 2 16

Reposted by Pauline Franz

Carlos Moreno-Yruela @carlosmyruela.bsky.social · Feb 4

#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates.
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky

1 17 43

Reposted by Pauline Franz

Rob Schneider @robertife.bsky.social · Dec 8

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup.
➡️Register now www.grc.org/histone-and-...

40 46

Reposted by Pauline Franz

Tim Triche, Jr.🔰 @timtriche.bsky.social · Dec 19

Dear world: this is what a graphical abstract is supposed to look like.

Pauline Franz @paulinefranz.bsky.social · Dec 19

What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!!

▶️ tinyurl.com/mvtecrsz

@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪

Frontispiece of Angewandte Chemie Int. Ed. showing a pop-art style drawing of protein structures and a hand symbolizing the protein RNF168.

1 6 33

Pauline Franz @paulinefranz.bsky.social · Dec 19

Check out our #openaccess article "A Site-Specific Click Chemistry Approach to Di-Ubiquitylate H1 Variants Reveals Position-Dependent Stimulation of the DNA Repair Protein RNF168"
▶️ tinyurl.com/27uxumme
@beatfierz.bsky.social

A Site‐Specific Click Chemistry Approach to Di‐Ubiquitylate H1 Variants Reveals Position‐Dependent Stimulation of the DNA Repair Protein RNF168

We developed a click chemistry approach to di-ubiquitylate histone H1 at relevant DNA repair-associated positions (H1KxUb2) to probe its effect on the E3 ligase RNF168. We demonstrate that H1KxUb2 st...

onlinelibrary.wiley.com

1 2 3

Pauline Franz @paulinefranz.bsky.social · Dec 19

What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!!

▶️ tinyurl.com/mvtecrsz

@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪

2 5 37

Reposted by Pauline Franz

Angewandte Chemie @angewandtechemie.bsky.social · Dec 10

Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!

13 45 220

Reposted by Pauline Franz

Nina Hartrampf @ninahartrampf.bsky.social · Dec 4

🥳 Today we celebrated the PhD defense of our very first PhD student Kevin Schiefelbein 🤩 Kevin told us about his Lasso Peptide journey over the past four years, and it was so great to see the full story coming together. Congratulations Kevin, and thank you for everything! #proudPI

3 26

Reposted by Pauline Franz

Altmetric @altmetric.com · Dec 2

Four panel meme based on the worst Star Wars film. Altmetric is tracking Myspace.

3 18 110

Reposted by Pauline Franz

Life Sciences Switzerland (LS2) @lifesciswitzerland.bsky.social · Nov 27

We want to thank everyone for joining and to congratulate the winners! A big thank you to all sponsors supporting this meeting!

We hope to see you all next time.
#LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science

2 5

Reposted by Pauline Franz

Micha Rapé Lab @micharapelab.bsky.social · Dec 3

Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI.

www.biorxiv.org/content/10.1...

8 35 120

Reposted by Pauline Franz

Micah G. Allen @micahgallen.com · Dec 2

Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!

A screenshot of a paper on bioarxiv illustrating the lack of blue sky share button!

9 200 390

Reposted by Pauline Franz

Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · Nov 25

Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️

34 240 500

Reposted by Pauline Franz

Simon Rössler @simonrossler.bsky.social · Nov 25

MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall. www.nature.com/articles/s41...

Cephalopod-inspired jetting devices for gastrointestinal drug delivery - Nature

Tethered or ingestible delivery systems that deliver liquid microjets in axial and radial directions can be used to deliver macromolecules to different parts of the gastrointestinal tract with good bi...

www.nature.com

1 1 6

Reposted by Pauline Franz

Waser Group @lcsolab.bsky.social · Nov 23

On November 20, the new class of peptide-cyanobenzene dye photocatalysts developed by Xingyu have been first made public in a preprint at ChemRxiv, including a great collaboration Wei Cai in the @beatfierz.bsky.social group and Dr. Anne Sophie Chauvin
chemrxiv.org/engage/chemr...

2 5

Reposted by Pauline Franz

Spirochrome @spirochrome.com · Nov 22

Celebrating #FluorescenceFriday and hopefully brightening your timeline with these live intestinal #organoids stained with our actin probe SPY555-FastAct.

SPY555-FastAct stained intestinal organoids growing in in microwells. the image is a composite of a brightfield image (grey) and SPY555-FastAct (cyan).

3 26

Reposted by Pauline Franz

Rita Strack @ritastrack.bsky.social · Nov 19

This the (short, funny, sad) video we got to see on imaging women's brains at the CZI Imaging meeting as part of Nina Miolane's talk. Worth a few minutes and worth a share. www.youtube.com/watch?v=tX5u...

2 25 54

Reposted by Pauline Franz

Alexis Rohou @alexisrohou.bsky.social · Nov 18

🚨 Attention #teamtomo PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here: roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...

2025 Summer Intern - Department of Structural Biology

Department Summary The CryoEM Group in the Department of Structural Biology is dedicated to providing high-resolution structural insights into biological macromolecules involved in health and disease....

roche.wd3.myworkdayjobs.com

2 32 35

Reposted by Pauline Franz

Altmetric @altmetric.com · Nov 18

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics

Action Intent Links | Bluesky

Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

docs.bsky.app

170 4.6K 11K

Reposted by Pauline Franz

Thorn-Seshold Lab @thornsesholdlab.bsky.social · Nov 17

📯📯 Chemical Biology starter pack 📯📯
140 PIs & groups posting primary research in chemical biology.

Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj

Let's make ChemBioSky even greater again!

#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange

48 120 140

Reposted by Pauline Franz

Razvan Borza @rborza.bsky.social · Nov 17

⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️

🔄Share to help people finding its topic/field

- STRUCTURAL BIOLOGY

Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...

39 180 290

Pauline Franz @paulinefranz.bsky.social · Nov 17

📌

Pauline Franz @paulinefranz.bsky.social · Nov 16

Thanks! Would you mind adding me as well?

1 1

Reposted by Pauline Franz

Rune Busk Damgaard @rbdamgaard.bsky.social · Nov 15

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn

6 48 49

Pauline Franz @paulinefranz.bsky.social · Nov 15

📌