Lightnews — Scholar-powered news

Reposted by RajuBrainLab

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 20d

Thanks @contagionlive.bsky.social for letting me put in some unscripted words

UC San Diego is the ideal place to receive your dream education or pursue a faculty career in collaborative medical or pharmaceutical sciences
@ucsandiego.bsky.social
@ucsdmedschool.bsky.social
@ucsdpharmacy.bsky.social

UC San Diego’s Collaborative Research Efforts, Community-Based Care Initiatives are in its DNA

Victor Nizet, MD, discusses how students can thrive at the university’s Skaggs School of Pharmacy and Pharmaceutical Sciences. He discusses the school's features including its rigorous coursework, foc...

www.contagionlive.com

2 6

RajuBrainLab @rajubrainlab.bsky.social · Jul 31

Congrats Mimi and team!

1

Reposted by RajuBrainLab

Prasad Jallepalli, MD, PhD @prasad.bsky.social · Jul 25

Before coming to NIH, Collins identified the gene that is mutated in cystic fibrosis (CF). Years later, this discovery led to the development of an innovative therapy for CF that's saved countless children.

This is why we fight.

www.nejm.org/doi/full/10....

1 13 28

Reposted by RajuBrainLab

John Prensner @johnprensner.bsky.social · Jul 10

As a #childhoodcancer doctor, I'm proud to be able to advocate for children with cancer in any way that I can.

Here is a piece that I recently wrote for #TheDetroitNews, who kindly published it.

#PEDCan
#CANSky

www.detroitnews.com/story/opinio...

Prensner: ‘Big Beautiful Bill’ betrays children with cancer

In the United States, we’ve fought to achieve the world’s best care for children with cancer.

www.detroitnews.com

1 12 23

Reposted by RajuBrainLab

Michael Taffe @effatma.bsky.social · Jul 3

This rapid action by the Prebys Foundation is the kind of thing I hope other regional philanthropies are doing. It isn't the entire solution by far but it is great to see them chipping in to help investigators in the San Diego academic science community.

www.prebysfdn.org/stories/blog...

Prebys Foundation Announces $7 Million in Emergency Support for Biomedical Research

www.prebysfdn.org

9 23

Reposted by RajuBrainLab

Politics and Health @politicshealth.bsky.social · Jul 3

Beyond taking #healthcare away from millions of kids, families, and the elderly, the Budget-Busting Bill would mean the loss of thousands of jobs in hospitals, research centers, nursing homes, clinics, doctors’ offices.
www.nytimes.com/interactive/...

How Health Care Remade the U.S. Economy (Gift Article)

Medicine is now the nation’s largest employer, but its growth may be slowing.

www.nytimes.com

12 85 220

Reposted by RajuBrainLab

Jennifer C @thejenniwren.teamlh.social · Jun 29

“I represent 67,000 pediatricians, and let me be clear: this bill will devastate children’s health,” said Dr. Susan Kressly, President of @ameracadpeds.bsky.social “Kids are 22% of our population—but 100% of our future. We cannot afford to fail them.”
Call your senators and demand a NO vote.

43 1.1K 2.4K

Reposted by RajuBrainLab

Eric Topol @erictopol.bsky.social · Jun 16

The promise and problems with multi-cancer early detection tests
by Sid Mukherjee @newyorker.com
www.newyorker.com/magazine/202...

The Catch in Catching Cancer Early

New blood tests promise to detect malignancies before they’ve spread. But proving that these tests actually improve outcomes remains a stubborn challenge.

www.newyorker.com

3 36 110

RajuBrainLab @rajubrainlab.bsky.social · Jun 4

Nice to see this important translational hurdle- crossing the BBB- highlighted in Nature! Of note is the point that it would be ideal to not only cross the BBB, but deliver therapeutics specifically to the CNS site of disease which current brain shuttles don’t do. Stay tuned:) #SelectinTherapeutics

Nature @nature.com · Jun 1

Brain shuttles - new technologies to traverse the blood-brain barrier - are showing promise in Alzheimer's, cancer, and more

https://go.nature.com/3T5WuF7

Brain drugs can now cross the once impenetrable blood–brain barrier

Nature - New technologies to shuttle drugs into the brain are showing promise in Alzheimer’s disease, cancer and more.

go.nature.com

1 5

Reposted by RajuBrainLab

Nature @nature.com · Jun 3

Nature research paper: The pivot penalty in research

https://go.nature.com/4dDz2bL

The pivot penalty in research - Nature

An analysis of millions of scientific papers and patents reveals a ‘pivot penalty’ when researchers shift direction, with the impact of studies decreasing rapidly the further they move from their previous work.

go.nature.com

6 22

Reposted by RajuBrainLab

Nicolas Robine @nicorobine.bsky.social · Jun 3

Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer
www.nature.com/articles/s43...

Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer - Nature Cancer

Based on a proteogenomic analysis, Perreault and colleagues report that the majority of predicted tumor antigens originate from unmutated genomic sequences in melanoma and non-small cell lung cancer.

www.nature.com

1 3 3

Reposted by RajuBrainLab

Jeremy Berg @jeremymberg.bsky.social · Jun 1

My quote of the day

If an elderly but distinguished scientist says that something is possible, he is almost certainly right; but if he says that it is impossible, he is very probably wrong.

Arthur C. Clarke

4 19 96

Reposted by RajuBrainLab

Children's Brain Tumor Network @wearecbtn.bsky.social · May 29

CBTN offers pediatric brain tumor data and samples to researchers worldwide for free. Request these resources to accelerate discoveries for kids: https://monkeylink.co/5c6c96

#WeAreCBTN #OpenScience

1 1

Reposted by RajuBrainLab

Society for Neuroscience @sfn.org · May 23

Cuts to NIH funding have dire consequences!

Neuroscience Professor Robert Greene shares why efforts to treat brain disease will suffer due to recent changes in U.S. government policies.

#Neurosky #AcademicChatter

1 3 4

Reposted by RajuBrainLab

Doctors for America @drsforamerica.bsky.social · May 7

Medicaid Covers

• 42% of all children nationwide
• 77% of children living in poverty in the U.S.
• 44% of children and youth with special health care needs nationwide
• 41% of births in the U.S.
• 37% of U.S. children with cancer
• 99% of children and youth in foster care

6 28 68

Reposted by RajuBrainLab

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · May 5

A Characterization of the Immune Cells in Immunocompetent and Immunodeficient Mice with Orthotopic Brain Tumors. https://www.biorxiv.org/content/10.1101/2025.04.29.651335v1

1 1

Reposted by RajuBrainLab

Sciences @sciences.skyfleet.blue · Apr 29

Cell classification should be based on more than just DNA

Letter to the Editor

www.nature.com

1 1

Reposted by RajuBrainLab

OncoDaily @oncodaily.bsky.social · Apr 6

Toxicity in phase III oncology clinical trials is often incompletely reported - Fumiko Ladd Chino
@fumikochino.bsky.social

oncodaily.com/opinion/fumi...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Fumiko Ladd Chino: Toxicity in phase III oncology clinical trials is often incompletely reported - OncoDaily

Fumiko Ladd Chino: Toxicity in phase III oncology clinical trials is often incompletely reported / Adina H Passy, Alexander D. Sherry, Avital M Miller,

oncodaily.com

1 7

Reposted by RajuBrainLab

Sallie Permar, MD, PhD @salliepermar.bsky.social · Mar 2

This bottleneck in research funding threatens research that took decades to build, as well as the cures of tomorrow. Publicly-funded research is the highest economic yield there is, with 2.5X of economic gains for every $.

Call your Senator and Rep to ask them to protect federal research!

Solid Evidence @solidevidence.bsky.social · Mar 1

So what's happening with medical research in the US? This is the cumulative award count from the NIH for the year.

Doesn't look so good.

But it gets worse.
1/

1 1

Reposted by RajuBrainLab

Matthew Kan @matthewkan.bsky.social · Mar 25

The NIH grant that has supported 38 years of training the best pediatrician-scientists in the country (I’m a proud former recipient) was cancelled. It was just approved for a 5 year renewal. The PSDP has supported the careers of many NIH-funded pediatrician-scientists and thought leaders

3 16 15

RajuBrainLab @rajubrainlab.bsky.social · Mar 26

We need more support now, not less, to train the next generation of pediatric-scientist leaders to give them the needed runway to develop novel therapies that will significantly impact the health and outcomes of children and their families.

2

RajuBrainLab @rajubrainlab.bsky.social · Mar 26

This is a really disappointing decision by the NIH to cancel the longstanding Pediatric Scientist Development Program (PSDP-K12) grant that has funded the early career development of numerous pediatric physician-scientists who have become the pediatric leaders in the US and the world.

1 2 5

Reposted by RajuBrainLab

Rachael Sirianni, PhD @docsirianni.bsky.social · Mar 20

Pediatric research. When grants are pulled, the infrastructure suffers
www.wcvb.com/article/bost...

2 20 54

Reposted by RajuBrainLab

John Prensner @johnprensner.bsky.social · Feb 25

On the front page of @cnn.com is a feature on how #NIH funding cuts might impact #childhoodcancer. Thanks to MJ Lee for spotlighting this issue, and I was glad to be able to contribute.

These kids deserve the best, not cuts!

#CANSky
#PEDSky

www.cnn.com/2025/02/25/h...

A kindergartner’s hopes for beating cancer are tied to federal grants now on the chopping block | CNN

A family whose 6-year-old is battling cancer says a move to slash funding by the National Institutes of Health (NIH) for research at universities and medical centers would be “devastating.”

www.cnn.com

14 28

Reposted by RajuBrainLab

Ardem Patapoutian @ardemp.bskyverified.social · Feb 23

Who benefits from US funding uncertainty? Hours after posting this, I got an email inviting me to China with a “package to support my research for 20 years.” Apparently, generous offers are available to all good scientists!🧪🧠

Ardem Patapoutian @ardemp.bskyverified.social · Feb 19

I expect that most academic biomedical researchers have considered leaving the US—if only in theory for now. What a colossal mess! Our representatives need to hear this. Please amplify so they know this matters. @levin.house.gov @repscottpeters.bsky.social @schiff.senate.gov @padilla.senate.gov

Hannah Harris Green @greennoise.bsky.social · Feb 19

“For the last 75 yrs, the NIH has been the biggest funder of biomedical research in the world. Most advances in medicine were seeded by NIH funding. When we became scientists, we just bought into this system. This is how it works. — @tuthill.bsky.social 🧵

www.theguardian.com/us-news/2025...

3 61 150