santiago, phd 🐈⬛
@santiagokique.bsky.social
Vnzln 🇻🇪 MD/PhD candidate @ Stanford 🌲
I study telomere biology in health and disease; I write about science and politics
blogs @ primafacie.substack.com
I study telomere biology in health and disease; I write about science and politics
blogs @ primafacie.substack.com
Pinned
the not so infinite typewriter
we left the typing monkeys alone and they're planting bombs under wall street
open.substack.com
new blog post on the ai bubble, why it won’t do what its backers need it to do, and why I think they keep getting duped that it will
open.substack.com/pub/primafac...
open.substack.com/pub/primafac...
November 27, 2025 at 4:53 PM
Reposted by santiago, phd 🐈⬛
this is amazing news - the HPV vaccine promises to eliminate cervical cancer in countries where uptake is high.
November 26, 2025 at 6:57 PM
this is amazing news - the HPV vaccine promises to eliminate cervical cancer in countries where uptake is high.
RIP Kotor remake
November 26, 2025 at 10:20 PM
RIP Kotor remake
Not hard to imagine a career-long HIV scientist would butt heads with Antivaximus prime at HHS and his lieutenant at NIH
November 25, 2025 at 4:16 AM
Not hard to imagine a career-long HIV scientist would butt heads with Antivaximus prime at HHS and his lieutenant at NIH
Reposted by santiago, phd 🐈⬛
Unfortunately, I can confirm that this is true.
I have known Carl for 2 decades and he is smart, dedicated, and quite apolitical, focused on science and getting stuff done on important problems.
Huge unnecessary loss of leadership and expertise.
I have known Carl for 2 decades and he is smart, dedicated, and quite apolitical, focused on science and getting stuff done on important problems.
Huge unnecessary loss of leadership and expertise.
Hearing news that Carl Dieffenbach, the Director of the Division of AIDS at #NIH (NIAID), has been removed from his position because he was "not aligned with HHS/OMB."
Russell Vought continues to remove great scientists as part of the Project 2025 mission to politicize and destroy NIH.
🧪 1/
Russell Vought continues to remove great scientists as part of the Project 2025 mission to politicize and destroy NIH.
🧪 1/
November 24, 2025 at 5:49 AM
Unfortunately, I can confirm that this is true.
I have known Carl for 2 decades and he is smart, dedicated, and quite apolitical, focused on science and getting stuff done on important problems.
Huge unnecessary loss of leadership and expertise.
I have known Carl for 2 decades and he is smart, dedicated, and quite apolitical, focused on science and getting stuff done on important problems.
Huge unnecessary loss of leadership and expertise.
New blog post on a curious rabbit hole I went down this past weekend thinking about a patient with apnea that led to the father of Toxicology by way of German mermaids. A 6 degrees of separation digression
open.substack.com/pub/primafac...
open.substack.com/pub/primafac...
the little mermaid's curse
the strange connection between automaticity and german mermaids
open.substack.com
November 25, 2025 at 4:12 AM
New blog post on a curious rabbit hole I went down this past weekend thinking about a patient with apnea that led to the father of Toxicology by way of German mermaids. A 6 degrees of separation digression
open.substack.com/pub/primafac...
open.substack.com/pub/primafac...
I actually think centrist Dems are more likely to support/endorse an MTG independent run for president than a progressive candidate that threatens a Newsom/Buttigieg type figure in the primary.
November 22, 2025 at 1:57 AM
I actually think centrist Dems are more likely to support/endorse an MTG independent run for president than a progressive candidate that threatens a Newsom/Buttigieg type figure in the primary.
Reposted by santiago, phd 🐈⬛
Breaking News: Robert F. Kennedy Jr. said he personally instructed the CDC to abandon its position that vaccines do not cause autism. The move underscores his determination to challenge scientific orthodoxy — in this case, that vaccines save lives — and bend the health department to his will.
RFK Jr. Says He Instructed CDC to Change Vaccines and Autism Language on Website
In an interview, Health Secretary Robert F. Kennedy Jr. cited gaps in vaccine safety research. His critics say he is ignoring a larger point: Vaccines save lives.
nyti.ms
November 21, 2025 at 6:56 PM
Breaking News: Robert F. Kennedy Jr. said he personally instructed the CDC to abandon its position that vaccines do not cause autism. The move underscores his determination to challenge scientific orthodoxy — in this case, that vaccines save lives — and bend the health department to his will.
English speaking world discovering Peak. If you’ve never seen this, would encourage sampling with the episode where one of the puppets is depressed
www.youtube.com/watch?v=lwYB...
www.youtube.com/watch?v=lwYB...
November 21, 2025 at 1:21 PM
English speaking world discovering Peak. If you’ve never seen this, would encourage sampling with the episode where one of the puppets is depressed
www.youtube.com/watch?v=lwYB...
www.youtube.com/watch?v=lwYB...
Reposted by santiago, phd 🐈⬛
November 18, 2025 at 8:24 PM
Every AI infrastructure graph looks like this. The exponential revenue generating event is always just around the corner and the capex commitments won’t get comically larger, we promise.
November 18, 2025 at 12:47 PM
Every AI infrastructure graph looks like this. The exponential revenue generating event is always just around the corner and the capex commitments won’t get comically larger, we promise.
Reposted by santiago, phd 🐈⬛
Bhattacharya's NIH made cuts to grants that disrupted trials, disproportionately impacting infectious disease trials & trials affecting minorities (e.g. trials on mitigating kidney disease, Alzheimer’s disease, & cervical cancer in minority populations).
These cuts were litigated in court.
1/x
These cuts were litigated in court.
1/x
A new study found the Trump administration’s cuts to NIH grants disrupted more than 380 clinical trials, affecting over 74,000 participants.
The cuts disproportionately impacted trials on infectious diseases and minority communities.
The cuts disproportionately impacted trials on infectious diseases and minority communities.
Federal cuts upended clinical trials. A new study reveals the toll.
Grants for 383 clinical trials were terminated and the funding disruptions affected more than 74,000 trial participants, according to new research.
www.washingtonpost.com
November 17, 2025 at 11:11 PM
Bhattacharya's NIH made cuts to grants that disrupted trials, disproportionately impacting infectious disease trials & trials affecting minorities (e.g. trials on mitigating kidney disease, Alzheimer’s disease, & cervical cancer in minority populations).
These cuts were litigated in court.
1/x
These cuts were litigated in court.
1/x
Reposted by santiago, phd 🐈⬛
I spent October traveling to schools throughout the South talking to students about American history. What I found were young people who understand we can tell a story that includes both the positive and the negative. As one 8th grader in Memphis said, “Doesn’t seem that hard, just say both things.”
Tell Students the Truth About American History
We owe it to Americans of all ages to be honest about the country’s past, including its contradictions.
www.theatlantic.com
November 17, 2025 at 4:57 PM
I spent October traveling to schools throughout the South talking to students about American history. What I found were young people who understand we can tell a story that includes both the positive and the negative. As one 8th grader in Memphis said, “Doesn’t seem that hard, just say both things.”
3 way parlay: AI bubble pops, larry summers rank stripped, Epstein files released. Read it back to me
November 17, 2025 at 1:15 PM
3 way parlay: AI bubble pops, larry summers rank stripped, Epstein files released. Read it back to me
I had a dream I was wondering in a dark neighborhood at night and walked into a giant mansion filled with exotic pets, including a Wolpertinger in a glass box. I asked the people inside “is that a fucking Wolpertinger?” and they said “oh yes it hasn’t learned not to bite the goats yet”
November 17, 2025 at 12:22 PM
I had a dream I was wondering in a dark neighborhood at night and walked into a giant mansion filled with exotic pets, including a Wolpertinger in a glass box. I asked the people inside “is that a fucking Wolpertinger?” and they said “oh yes it hasn’t learned not to bite the goats yet”
It’s not going to do any of those things to any extent where the word “do” would have meaning.
Anthropic CEO Dario Amodei thinks AI could help find cures for most cancers, prevent Alzheimer’s, and even double the human lifespan. cbsn.ws/4oRZ8Nm
November 17, 2025 at 1:21 AM
It’s not going to do any of those things to any extent where the word “do” would have meaning.
Reposted by santiago, phd 🐈⬛
Reposted by santiago, phd 🐈⬛
Current vibe
November 14, 2025 at 12:26 AM
Current vibe
Reposted by santiago, phd 🐈⬛
They are straight up robbing taxpayers blind at this point and not even trying to hide it. Just ransacking the treasury out in the open. This motherfucker pleaded guilty! www.bloomberg.com/news/article...
Michael Flynn, DOJ in Settlement Talks Over $50 Million Claim
The Justice Department has been discussing settlements with two former officials from Donald Trump’s first term who — like the president — claim they’re owed major payouts from the US government as vi...
www.bloomberg.com
November 14, 2025 at 8:16 PM
They are straight up robbing taxpayers blind at this point and not even trying to hide it. Just ransacking the treasury out in the open. This motherfucker pleaded guilty! www.bloomberg.com/news/article...
Reposted by santiago, phd 🐈⬛
"If we’re going to call ourselves writers, we have more than just an obligation to write, we have some obligation to stand in defense of language as a conduit for meaning rather than language as an antagonist to meaning." Omar El Akkad janeratcliffe.substack.com/p/finding-co...
Finding Community: A Conversation with Omar El Akkad
On the obligation of witness, erasure of history, the damage of insatiable systems, language as a conduit for meaning, the choice of hope, and the joy of community.
janeratcliffe.substack.com
November 14, 2025 at 4:27 AM
"If we’re going to call ourselves writers, we have more than just an obligation to write, we have some obligation to stand in defense of language as a conduit for meaning rather than language as an antagonist to meaning." Omar El Akkad janeratcliffe.substack.com/p/finding-co...
Reposted by santiago, phd 🐈⬛
NEW: Authorities said Tren de Aragua “terrorists” had taken over the building. A ProPublica investigation found little evidence to back up the government’s claims.
For the first time, the Venezuelans arrested in a Chicago raid are telling their stories.
For the first time, the Venezuelans arrested in a Chicago raid are telling their stories.
“I Lost Everything”: Venezuelans Were Rounded Up in a Dramatic Midnight Raid but Never Charged With a Crime
Authorities said Tren de Aragua “terrorists” had taken over the building. A ProPublica investigation found little evidence to back up the government’s claims. For the first time, the Venezuelans arrested in a Chicago raid are telling their stories.
www.propublica.org
November 13, 2025 at 1:00 PM
NEW: Authorities said Tren de Aragua “terrorists” had taken over the building. A ProPublica investigation found little evidence to back up the government’s claims.
For the first time, the Venezuelans arrested in a Chicago raid are telling their stories.
For the first time, the Venezuelans arrested in a Chicago raid are telling their stories.
Reposted by santiago, phd 🐈⬛
For folks (and journalists) who want to search the Oversight Committee email texts, I made a database for searching the 20k text files:
splendorous-chaja-f79791.netlify.app
splendorous-chaja-f79791.netlify.app
Epstein Document Search
splendorous-chaja-f79791.netlify.app
November 13, 2025 at 1:12 AM
For folks (and journalists) who want to search the Oversight Committee email texts, I made a database for searching the 20k text files:
splendorous-chaja-f79791.netlify.app
splendorous-chaja-f79791.netlify.app