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Biozentrum, University of Basel @biozentrum.unibas.ch · 11d

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

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Ben Engel @cellarchlab.com · 15d

Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on!

#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵

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Sven Klumpe @svenklumpe.bsky.social · Aug 15

Extremely excited for the second version of this workshop at the MPI of Biophysics l, Frankfurt, that will happen 12-20. April 2026. Absolutely amazing lineup of speakers, I am very much looking forward to learning from everyone! Apply here: meetings.embo.org/event/26-in-...

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Biozentrum, University of Basel @biozentrum.unibas.ch · Aug 4

Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of research group and other incentives. The summer call is open until October 12, 2025. bit.ly/4caiqqX @biozentrum.unibas.ch @unibas.ch #fellowship #PhD#Switzerland

Biozentrum PhD Fellowships

Share your passion for life sciences. If you are talented and highly motivated, want to broaden your horizons and are interested in a wide range of research topics, apply for one of the sought after B...

bit.ly

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Manon Demulder @manondemulder.bsky.social · Jun 30

Our first DinoSphere seminar is this Tuesday, 1 July at 9 AM CEST! A good way to start the day if you're in Europe ☕

We will hear from Yong Heng Phua (OIST) and Karel Mocaer (Heidelberg)
🔗 Zoom link on our website: tinyurl.com/4duvwtvp

DinoSphere - Online talks

Video credits: Liz Cooney

tinyurl.com

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Florian Wollweber @florianwollweber.bsky.social · Jun 27

After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6

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Manon Demulder @manondemulder.bsky.social · Jun 4

We’re kicking off the DinoSphere Online Seminar Series! Join us for our first session with Karel Mockaer (Heidelberg) & Yong Heng Phua (OIST)

📅 1 July 9AM CEST
🔗 tinyurl.com/4mjaverj

Spread the word!
@protistwtmostest.bsky.social @ehehenberger.bsky.social @chandnibhickta.bsky.social&Norico Yamada

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Matt Johnson @profmattjohnson.bsky.social · May 21

Pleased to share my very general review of Photosynthesis now published in Nature Reviews Mol Cell Biol
🌞🌱
rdcu.be/em1lz Hopefully a useful primer for Postgrad and undergrad students

Structure, regulation and assembly of the photosynthetic electron transport chain

Nature Reviews Molecular Cell Biology - The electron transfer chain in chloroplast thylakoid membranes uses solar energy to produce NADPH and ATP, which power carbon fixation into biomass. This...

rdcu.be

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George Currie @georgealfredcurrie.bsky.social · May 19

Does publishing serve science or is science serving publishing?

Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it.

onlinelibrary.wiley.com/doi/10.1002/...

#OpenScience

Screenshot of article summary of: Toward Science-Led Publishing
by Damian Pattinson, George Currie

published as an opinion piece, in Learned Publishing

Summary

The current dynamic of scholarly publishing prioritises the wants of the publishing industry over the needs of the research community.

This article explores this theme through the lens of ‘publisher-led science’ as a description of our current status quo, and through ‘science-led publishing’ as an improved future state.

We argue that financial motivations central to most publishing distort how research is presented, how it is assessed and even what research is undertaken, leading to a system that hinders, rather than facilitates, scientific progress.

We propose three elements of a science-led publishing approach that would accelerate research communication, incentivise collaboration between authors, editors and reviewers, and create a more transparent and equitable research landscape.

We believe that research funding and research assessment are two of the primary levers for wider change in research and research culture and consider the future purpose of scholarly publishing in a world where these proposals have been widely adopted.

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Philippe Van der Stappen @phaips.vd.st · May 6

Hey #TeamTomo,
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!

tomoguide.github.io

Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪

Welcome to TomoGuide

A step-by-step Cryo-ET guide

tomoguide.github.io

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Florent Waltz @florentwaltz.bsky.social · May 6

You want to start tomography? Solve structures inside cells? Reach Nyquist 😳 ? @phaips.vd.st and I have a website for you! tomoguide.github.io
You'll find a tutorial on how to reconstruct tomograms, pick particles and do subtomogram averaging, using different software!
Hope it will be useful !

3.8 angstrom resolution ribosome from 33 tomograms

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Lorenz Lamm @lorenzlamm.bsky.social · Apr 25

🦠🧠 MemBrain update! 🧠🦠
We’ve updated our preprint! It now covers the full MemBrain v2 pipeline for end-to-end membrane analysis in #CryoET: segmentation, particle picking, and spatial statistics.
🔗 Preprint: doi.org/10.1101/2024...
🔗 Code: github.com/CellArchLab/...
🧵(1/6) #TeamTomo

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Philipp Erdmann @3p1l.bsky.social · Apr 22

Hey Everyone!❄️🔬 We have two fully funded PhD positions @humantechnopole.bsky.social this year!
Help us understand better how one of the main stress regulators - the nucleolus - integrates synaptic inputs!🧠Find all the calls - also from my amazing colleagues - here: www.semm.it/education/ho...

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woj_wie @wojwie.bsky.social · Apr 3

Great picture. Daliesque.

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Florian Wollweber @florianwollweber.bsky.social · Mar 21

Asgard archaea are full of surprises, this time we found (tiny) microtubules (snapshots of microtubule evolution?!) - Check out our new paper on the cytoskeleton of Lokiarchaeum ossiferum: www.cell.com/cell/fulltex...

Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · Mar 21

Asgard archaea have actin - but what about microtubules? Where do they come from? 🧐 Our new paper www.cell.com/cell/fulltex... by @xujwet.bsky.social & @florianwollweber.bsky.social, in collaboration with the Schleper & Wieczorek labs, describes tiny Asgard microtubules! #TeamTomo #ArchaeaSky 1/6

Credit: Margot Riggi (@margotriggi.bsky.social), Max-Planck Institute of Biochemistry (@mpibiochem.bsky.social)

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Florent Waltz @florentwaltz.bsky.social · Mar 20

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉
You can find the full story here www.science.org/doi/10.1126/...
@verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

Science Magazine @science.org · Mar 20

In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more in this week's issue: scim.ag/3FA3Ygq

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Katharina Geißler @kgeissler.bsky.social · Mar 15

Check out @deglushk.bsky.social 's method to measure membrane thickness in cryo electron tomograms!

bioRxivpreprint @biorxivpreprint.bsky.social · Mar 14

In situ evidence for systematic membrane thickness variation across cellular organelles https://www.biorxiv.org/content/10.1101/2025.03.13.642912v1

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Richard Sever @richardsever.bsky.social · Mar 11

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

Homepage - openRxiv

openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.

openrxiv.org

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Carl T. Bergstrom @carlbergstrom.com · Mar 6

Let's talk about this Nature piece in more detail.

I've rarely read something so anti-scientific anywhere short of the National Review.

www.nature.com/articles/d41...

Three AI-powered steps to faster, smarter peer review

Tired of spending countless hours on peer reviews? An AI-assisted workflow could help.

www.nature.com

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Sven Klumpe @svenklumpe.bsky.social · Mar 5

Happy to share our manuscript on the in situ visualization of the copia retrotransposon in its final form today published in @cellcellpress.bsky.social www.cell.com/cell/fulltex.... What’s new?

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Ricardo D. Righetto @lifeonthewedge.bsky.social · Feb 28

To all #TeamTomo #CryoET and #Chlamydomonas aficionados: we have updated EMPIAR-11830 with a bug fix concerning some cryo-CARE denoised tomos as well as additional files and metadata! 🎉👩🏽‍💻

www.ebi.ac.uk/empiar/EMPIA...

A little thread about what's new... 🧵 1/n

Rare cellular events observed in the cryo-ET dataset. Slices through tomograms (left) with corresponding 3D segmentation (middle and right). Right panels show enlarged views of the boxed regions in the middle panels. A) Mitochondrion at the plasma membrane, tethered to microtubules by thin filaments of unknown identity. Segmented classes: nuclear envelope (light blue), nuclear pore complex (dark blue), 80S ribosomes (orange), mitochondrial membranes (dark red), ATP synthase (royal blue), plasma membranes (grey), microtubules (pink), filaments (yellow), endoplasmic reticulum (purple). Zoomed-in panel shows thin filaments running between microtubules and the mitochondrion at the plasma membrane. Note that this tomogram contains two closely appressed cells, and thus, two plasma membranes with cell walls between. B) Mitochondrial fission event with ER membrane interactions. Segmented classes: mitochondrial membranes (dark red), ATP synthase (royal blue), 80S ribosomes (orange), thylakoid membranes (green), PSII (bright yellow), cell wall (grey), ER (purple), fission site containing filamentous structures perpendicular to the mitochondrial long axis (pale yellow). C) Ciliary transition zone between basal body and axoneme, including assembling IFT train and stellate structure77. Segmented classes: microtubule doublets (light blue), central microtubule pair (light green), stellate structure (pale red), IFT train (yellow). D) Pyrenoid tubule extending from the thylakoids into the phase-separated Rubisco matrix of the pyrenoid. Minitubules originate from thylakoid membranes82. Segmented classes: thylakoid membranes (dark green), PSII (yellow), pyrenoid tubule (lime green), Rubisco (lavender blue), minitubules (orange). Scale bars in A-D: 100 nm. Related to Fig. 2C-H.

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Lorna Malone @drlornamalone.bsky.social · Feb 18

📢 Registration is now open for 'Wellcome-MRC Cryo-EM in Structural Biology 2025'!

📅 Join us online March 3-7 at @diamondlightsource.bsky.social @universityofleeds.bsky.social for lectures & demos in #CryoEM & #CryoET: sample prep, SPA, model building & more!🧬

🔗 www.diamond.ac.uk/Instruments/...

Wellcome-MRC Cryogenic Electron Microscopy in Structural Biology 2025 - - Diamond Light Source

eBIC (Diamond light source) has partnered with the Astbury Biostructure Lab (University of Leeds), the Scottish Centre for Macromolecular Imaging (University of Glasgow), Midlands Regional Cryo-EM Fac...

www.diamond.ac.uk

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Marcel Dickmanns | 🌿❄️🔬 @madic.bsky.social · Feb 19

Our methods paper made it to bioRxiv:
doi.org/10.1101/2025...

Full #cryoET workflows for #plant tissues. Plus some general tricks and tweaks on serial Lift-Out and cryo-FLM. 🧪🧵1/5

#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM #CLEM

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Sven Klumpe @svenklumpe.bsky.social · Feb 4

Extremely excited to be joining the vibrant community of the Vienna BioCenter to build up cryo-ET and cryo-FIB milling on campus soon!

IMP @impvienna.bsky.social · Feb 4

We will soon welcome @svenklumpe.bsky.social to the Vienna BioCenter, where he will use cryo-Electron Tomography to study - among other things - how #transposons shape #germlines. Sven's lab will be @imbavienna.bsky.social *AND* the IMP.

Full story: www.viennabiocenter.org/about/news/s...

Sven Klumpe to start cryo-Electron Tomography lab at IMP and IMBA

The Vienna BioCenter institutes IMP and IMBA will soon host a joint research group headed by Sven Klumpe. The structural biologist will join the two institutes with an innovative double-affiliation to...

www.viennabiocenter.org

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Sjors Scheres @sjorsscheres.bsky.social · Feb 4

Give control to shareholders, and enshittification will happen, where a relentless drive for growth will reduce quality for users. It would be cheaper and better to keep companies away from control over scientific publishing. Scientists do most of the work anyway. Look at @elife.bsky.social!

Marcus Leaning @marcusleaning.bsky.social · Feb 3

#academicsky
A good piece on uk universities and the Elsevier OA deal...
blogs.lse.ac.uk/impactofsoci...

Why are universities ending their Elsevier open access agreements?

After recent reporting that three UK universities had ended their transitional open access agreements with the publisher Elsevier, Peter Barr explains why academic libraries are making these decisi…

blogs.lse.ac.uk

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