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Reposted by Arslan Zaidi

Gen Wojcik @genandgenes.bsky.social · 2d

Whoops, wrong hashtag.

If you are going to #ASHG25, check out the line-up!

This is perfect if you are a trainee who needs to network but has no idea how to do it. Instead of trying to corner someone at the posters (which is stressful!), schedule a slot and sit down for 15 minutes to chat!

Gen Wojcik @genandgenes.bsky.social · 2d

Are you going to #ASHG2025 next week in Boston? Interested in getting some mentorship from leading figures in the field (and me)?

Check out our speed mentoring event on Thursday! Sign-ups are online so reserve a spot ASAP.

site.pheedloop.com/event/ASHG25...

PheedLoop

PheedLoop: Hybrid, In-Person & Virtual Event Software

site.pheedloop.com

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Arslan Zaidi @aazaidi.bsky.social · 7d

Yes to both. Coverage can be uneven so good to be sure but probably overkill for mtDNA

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Arslan Zaidi @aazaidi.bsky.social · 7d

We’ve done the former with mt genomes. I believe you end up with ./. calls for sites where only a few individuals carried an alt allele. So there’s an extra step (we wrote a script) to go through and fill those in with ref after making sure there were enough reads supporting that site

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Jazlyn Mooney @jazlynmooney.bsky.social · 16d

Super excited to see our reference bias work out in Cell! Reviewers gave us some excellent ideas, and Maria added on some new analyses that broke down how SNPs from heterospecific references mapped or did not map in a conspecific reference.

Maria Akopyan, PhD @akopyan.bsky.social · 16d

Now published in Cell! We found that ~15% of SNPs from divergent refs did not liftover as SNPs in the gray fox ref—half mapped to monomorphic sites, half failed to map. Co-authored with Matthew Genchev, @elliecat.bsky.social, and @jazlynmooney.bsky.social

www.sciencedirect.com/science/arti...

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Jeffrey Ross-Ibarra @jrossibarra.bsky.social · Sep 3

Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!

Homepage - Population, Evolutionary, and Quantitative Genetics Conference

Visit our website to learn more.

genetics-gsa.org

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Pleuni Pennings @pleunipennings.bsky.social · Aug 29

I made a video about my new paper. I hope you enjoy it!

vimeo.com/1113132836?s...

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Arslan Zaidi @aazaidi.bsky.social · Aug 23

Commensurate with his presence 😂🤣

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Arslan Zaidi @aazaidi.bsky.social · Aug 23

Another fun year for the #mwpg, this year at the University of Minnesota! Great to see all the trainees participating with their cool work.

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Arslan Zaidi @aazaidi.bsky.social · Aug 13

Huge congratulations to my friend @mitopr.bsky.social on being selected as a Pew Biomedical Scholar!

www.pew.org/en/projects/...

Maria A. Nieves-Colón, Ph.D.

My research will investigate the genetic and health impacts of the influx of millions of Africans to Latin America during the colonial period.

www.pew.org

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Gregor Gorjanc @gregorgorjanc.bsky.social · Aug 11

AlphaSimR course edin.ac/3wfGSEj Week 3 opens with a discussion on genetic variation between relatives, with a focus on siblings. While mutation is the ultimate source of genetic variation (by introducing new alleles), recombination shuffles the existing genetic variation through meiosis.

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Arslan Zaidi @aazaidi.bsky.social · Aug 6

Many Congratulations Roshni!!

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Genetics Society of America @genetics-gsa.bsky.social · Jul 28

New in #GENETICS: Huang et al. describe biases in SNP & local ancestry heritability as functions of admixture history and the genetic architecture of the trait, clarifying their interpretation and implication for #GWAS & polygenic prediction in population admixture.

Read more: buff.ly/1xB3Mpu

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Arslan Zaidi @aazaidi.bsky.social · Jul 27

There’s nothing we can do. Every non violent form of protest has been tried and now even that can land you in prison. The brave carry on and the rest of us mourn the loss of our collective humanity.

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EvolDir @evoldir.bsky.social · Jul 24

The Mathieson Lab at the University of Pennsylvania is hiring a computational postdoc in machine learning and evolutionary biology. Apply with a CV and references: [email protected]. More info: https://saramathieson.github.io/lab #postdoc

We are a computational lab focusing on developing machine learning algorithms for biological data. Currently we are working on inference tasks related to natural selection and demographic inference, as well as generative models for genomic data from humans, mosquitos, and other species.

saramathieson.github.io

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bioRxiv Genetics @biorxiv-genetic.bsky.social · Jul 17

Effects of ancestry, agriculture, and lactase persistence on the stature of prehistoric Europeans https://www.biorxiv.org/content/10.1101/2025.07.11.664181v1

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Arslan Zaidi @aazaidi.bsky.social · Jul 14

Short answer: twin estimates aren’t inherently wrong but they’re not the end all be all either.

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Arslan Zaidi @aazaidi.bsky.social · Jul 14

Human geneticist here. I don’t think we have a gold standard. The estimands are different across approaches bc they make different assumptions esp about the true trait architecture. The true arch is unknown but the hope is diff estimates will converge once we rule out artifacts, confounding etc

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Arslan Zaidi @aazaidi.bsky.social · Jul 10

last day tomorrow to register for a talk/poster at Midwest popgen. Please RT(? is that what they say here?)!

Esha Bandyopadhyay, Ph.D. @eshabandyopadhyay.bsky.social · Jul 1

Please register if you haven't already done so.
MidWest PopGen is happening in August at the University of Minnesota (Twin Cities)—abstract deadline for talk: July 11th, and poster: August 1st.

sites.google.com/umn.edu/mwpg...

MWPG2025

Join us for the 10th Midwest Population Genetics conference, held at the University of Minnesota Twin Cities from August 21 - August 22, 2025.

sites.google.com

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Florian Privé @privefl.bsky.social · Jul 4

I probably won't have time to make a video out of this.

But the materials are available online, and should be pretty self-explanatory.

Hope this is useful to some people.

privefl.github.io/statgen-cour...

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Arslan Zaidi @aazaidi.bsky.social · Jul 2

Maybe they’re not washing their hands thoroughly after not using water in the bathroom.

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Esha Bandyopadhyay, Ph.D. @eshabandyopadhyay.bsky.social · Jun 9

Thrilled to see the latest work from the lab (@genscapelab.bsky.social) out in Current Biology! Congratulations @jaurban2204.bsky.social ! 🎉

Grateful to have had the chance to contribute to this effort.

Toño Urban Aragon @jaurban2204.bsky.social · Jun 9

Delighted to share that one of my major PhD projects has been published today in Current Biology.

In this paper, we look into the genetic population structure and demographic histories of two populations in Sri Lanka: the Sinhalese and Adivasi [1/n]. www.cell.com/current-biol...

Population histories of the Indigenous Adivasi and Sinhalese from Sri Lanka using whole genomes

Sri Lanka is home to diverse ethnic groups with different genetic histories. Urban Aragon et al. find that despite close genetic affinities, Indigenous Adivasi have more hunter-gatherer ancestry and l...

www.cell.com

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Esha Bandyopadhyay, Ph.D. @eshabandyopadhyay.bsky.social · Jul 1

Please register if you haven't already done so.
MidWest PopGen is happening in August at the University of Minnesota (Twin Cities)—abstract deadline for talk: July 11th, and poster: August 1st.

sites.google.com/umn.edu/mwpg...

MWPG2025

Join us for the 10th Midwest Population Genetics conference, held at the University of Minnesota Twin Cities from August 21 - August 22, 2025.

sites.google.com

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Eimear Kenny @eimearekenny.bsky.social · Jun 17

📢 Just posted: Our preprint introducing SPC — Spectral Components — is now live on medRxiv!

Led by Dr. Ruhollah Shemirani and years in the making, this method offers a robust, scalable way to adjust for recent population structure in genomic analyses.
🔗 www.medrxiv.org/content/10.1...

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SPC: a SPectral Component approach to address recent population structure in genomic analysis

Population structure is a well-known confounder in statistical genetics, particularly in genome-wide association studies (GWAS), where it can lead to inflated test statistics and spurious associations...

www.medrxiv.org

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Arslan Zaidi @aazaidi.bsky.social · Jun 14

Website and hotel info for Midwest popgen. Please register (free!) and book rooms asap to get ahead of the State Fair crowd.

The world may be aflame but we can try to find some community with each other. #mwpg25 slogan?

sites.google.com/umn.edu/mwpg...

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Mashaal Sohail @mashaals.bsky.social · Jun 10

Our new work is now out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with @delvecchyo.bsky.social and Emilia Huerta-Sanchez, led by Valeria Añorve-Garibay.

The American Journal of Human Genetics @ajhgnews.bsky.social · Jun 10

📣Online now!
📄Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples
🧑‍🤝‍🧑 @delvecchyo.bsky.social @mashaals.bsky.social & co

Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples

Using polygenic scores, we find that two types of natural selection, stabilizing selection and directional selection, can decrease the prediction accuracy of complex traits in ancient individuals. We ...

www.cell.com

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