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Andreas Beyer Group @beyerlab.bsky.social · 8d

That is what the molecular aging clocks are doing: they measure the accummulation of stochastic molecular damage. Since those clocks are in use for many years already, the ansewer is: yes, we are doing this.

Reposted by Andreas Beyer Group

Sara Wickstrom @sarawickstrom.bsky.social · 27d

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

Computational image analyst (m/f/d)

The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a

jobs.mpi-muenster.mpg.de

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Andreas Beyer Group @beyerlab.bsky.social · 16d

This review of our @crc1678.bsky.social member @bjornschumacher.bsky.social and @meyerdh.bsky.social is greatly summarizing fundamentals of the molecular biology of aging. What causes aging? Read the answer!

Björn Schumacher @bjornschumacher.bsky.social · 19d

🔥🔥🔥Out now: our Perspectives article in @nataging.nature.com outlining how aging is driven by molecular damage leading to increasing molecular noise whose quantification could track aging with the precision of a clock @meyerdh.bsky.social @alexeimaklakov.bsky.social
www.nature.com/articles/s43...

Aging by the clock and yet without a program - Nature Aging

Meyer and colleagues refute the idea that, as aging can be tracked precisely by clocks, it must be driven by a biological program. They propose that imperfect maintenance and repair processes resultin...

www.nature.com

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Andreas Beyer Group @beyerlab.bsky.social · Sep 7

Our PhD student @larahi.bsky.social l is now in Zurich @ethz.ch in the @picottilab.bsky.social with funding from @crc1678.bsky.social
Lara, enjoy your time on the Hönggerberg 🏔️ in one of the best proteomics labs of the world!! 🧪

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Reposted by Andreas Beyer Group

CRC1678 @crc1678.bsky.social · Sep 4

🚀 Don’t miss out the poster of our #CRC1678 member @nishahemandhar.bsky.social at the #EMBL Protein Conference — hands down, one of the most mind-blowing presentations out there! 🤯🤯

Nisha Hemandhar @nishahemandhar.bsky.social · Sep 4

I'll be presenting our latest work, that explores proteo-transcriptomic changes that occur with brain aging and their impact on protein synthesis at the #EMBLProtein conference.

If you want to know more about it, come and spin my poster #129.
#proteinsynthesis #brainaging

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Andreas Beyer Group @beyerlab.bsky.social · Sep 7

Fantastic poster!

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Andreas Beyer Group @beyerlab.bsky.social · Sep 3

Congrats to to our #CRC1678 member @ignatovalab.bsky.social 🎉

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Reposted by Andreas Beyer Group

CRC1678 @crc1678.bsky.social · Aug 29

📣CRC 1678 is funding research visits for three early career scientists!
🔬 @thancbn.bsky.social visits @landthalerm.bsky.social @ MDC Berlin
🧬 @larahi.bsky.social & Car Elias Kutzner visit @picottilab.bsky.social @ ETH Zürich
We wish our fellows an inspiring and productive time abroad!

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Andreas Beyer Group @beyerlab.bsky.social · Sep 3

Congrats to David and team also for this one!!

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Andreas Beyer Group @beyerlab.bsky.social · Sep 3

Congratulations to our #CRC1678 member David!!!

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Andreas Beyer Group @beyerlab.bsky.social · Aug 2

Congratulations to our new postdoc Domenico DiFraia for his amazing paper in @science.org! 🥂 A tour de force on brain aging in the killifish. 🐟 Transcriptomics, proteomics, including ribosome profiling, PTMs, etc... Translation is key for understanding brain aging!🧬🎉
www.science.org/doi/10.1126/...

Altered translation elongation contributes to key hallmarks of aging in the killifish brain

Aging is a major risk factor for neurodegeneration and is characterized by diverse cellular and molecular hallmarks. To understand the origin of these hallmarks, we studied the effects of aging on the...

www.science.org

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Reposted by Andreas Beyer Group

Robert Hänsel-Hertsch @epistrucstab.bsky.social · Jul 28

🧪Move over CUT&Tag, there’s a new #TranscriptionFactor mapping method in town.
Our newly developed DynaTag is faster, cleaner, more sensitive than #ChIPseq, #CUT&RUN and #CUT&Tag.
🔗 Our @natcomms.nature.com paper: www.nature.com/articles/s41...
🧵Let’s break down what makes DynaTag so powerful (1/7)

Image credit: @gloglita.bsky.social‬ @lifescienceeditors.bsky.social‬ captured DynaTag in action: a pA-Tn5 probe (multicoloured) binds an antibody (white), which binds p53 DNA-binding domain (green) on DNA (blue) within 2 nucleosomes

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Reposted by Andreas Beyer Group

Trentini Lab @trentini-lab.bsky.social · Aug 1

🚨 Happy to share our first pre-print 🎉 on the causes of ribosome-associated degradation of CFTR and other transmembrane proteins.
We explore how protein folding, ER insertion, and elongation dynamics influence translation arrests in this new class of RQC targets.👇
www.biorxiv.org/content/10.1...

Principles of ribosome-associated protein quality control during the synthesis of CFTR

Prolonged translational arrests caused by defective mRNAs activate the ribosome-associated protein quality control (RQC) pathway, which marks harmful incomplete proteins for degradation. Multipass tra...

www.biorxiv.org

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Andreas Beyer Group @beyerlab.bsky.social · Jul 20

This was fantastic! So much fun, so nice people and a lot of exciting discussions about science, life and everything ✨🧬👩‍🔬🥂🎳 #CRC1678 #ECRetreat #ScienceCommunity

CRC1678 @crc1678.bsky.social · Jul 14

Today marks the first day of our very first CRC 1678 Early Career Researcher Retreat! We’re proud to have such an amazing group of scientists with us—full of curiosity, energy, and team spirit. 💥🧠 🥳💪 #CRC1678 #ECRetreat #ScienceCommunity

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Reposted by Andreas Beyer Group

CRC1678 @crc1678.bsky.social · Jul 14

Today marks the first day of our very first CRC 1678 Early Career Researcher Retreat! We’re proud to have such an amazing group of scientists with us—full of curiosity, energy, and team spirit. 💥🧠 🥳💪 #CRC1678 #ECRetreat #ScienceCommunity

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Reposted by Andreas Beyer Group

CRC1678 @crc1678.bsky.social · Jul 11

Freshly launched! 🚀 Check out the new CRC 1678 website 🌐
👉 crc1678.uni-koeln.de

About CRC 1678 - CRC1678 - Collaborative Research Center

CRC 1678 investigates how age and stress-driven declines in the accuracy of mRNA and protein production affect cellular and organismal health. By taking an

crc1678.uni-koeln.de

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Reposted by Andreas Beyer Group

Joris Deelen @jorisdeelen.bsky.social · May 29

I am very proud to present you the first paper from the main research line of my group at the @mpiage.bsky.social in collaboration with my current group @molepi.bsky.social @bds-lumc.bsky.social at the LUMC, which is now published in @geroscience.bsky.social!

link.springer.com/article/10.1...

Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants - GeroScience

Human longevity, which is coupled to compression of age-related disease, is a heritable trait. However, only few common genetic variants have been linked to longevity, suggesting that rare, family-spe...

link.springer.com

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Reposted by Andreas Beyer Group

Cologne Graduate School of Ageing Research @cga-age.bsky.social · Jul 8

🚨 Your PhD journey starts NOW! Join our #webinar on Sept 4, 1-3 PM (CEST) & explore #PhD opportunities at Max Planck's IMPRS in NRW, Germany! 🇩🇪
👀 Gain insights into groundbreaking research & register here: events.gwdg.de/e/PhDatMaxPl... #MaxPlanck #Research #Germany #Science

Image shows diverse students with different backgrounds interested in getting informed about their career opportunities. Writing says "Rock your Career".

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Andreas Beyer Group @beyerlab.bsky.social · Jul 9

Welcome Alice! Great to have you here!

CRC1678 @crc1678.bsky.social · Jul 9

Currently our Mercator Fellow Alice E. Lee from Harvard Medical School is visiting us. We very much welcome Alice in Cologne and we are looking forward to many stimulating discussions with her! 👉 labs.childrenshospital.org/lee-lab

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Reposted by Andreas Beyer Group

Nature Aging @nataging.nature.com · Jun 2

Online now!✨RESEARCH: Gkioni et al @mpiage.bsky.social show that trametinib and rapamycin treatment combine additively to extend lifespan and healthspan in female and male mice, reducing tumor growth and inflammation www.nature.com/articles/s43... rdcu.be/eo3gS

The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespan - Nature Aging

Gkioni et al. show that trametinib, which targets the Ras–Mek–Erk pathway, extends lifespan in male and female mice and that co-treatment with the known geroprotector rapamycin additively extends life...

www.nature.com

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Reposted by Andreas Beyer Group

CECAD Cologne @cecad.bsky.social · May 19

👏 Congratulations to Professor Aleksandra Trifunovic on receiving the Max Delbrück Research Prize 2025 from the University of Cologne for her groundbreaking work on #mitochondria, #aging, and cellular stress responses. A proud moment for #CECAD!

➡️ uni.koeln/Y6WSC

@unicologne.bsky.social

Aleksandra Trifunovic receives Max Delbrück Research Prize 2025

CECAD congratulates Professor Aleksandra Trifunovic on receiving the University of Cologne’s Max Delbrück Prize for her pioneering contributions to mitochondrial biology.

uni.koeln

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Reposted by Andreas Beyer Group

CECAD Cologne @cecad.bsky.social · May 22

CECAD receives renewed DFG funding! 🎉 We continue to unlock the biology of aging 🧬 and advance healthy aging for all! 👵👴

➡️ uni.koeln/GAPGK

#CECAD #AgingResearch #ExcellenceCluster #DFG #HealthyAging @unicologne.bsky.social

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Andreas Beyer Group @beyerlab.bsky.social · May 22

This was a great event! Very inspiring and collaborative.

Björn Schumacher @bjornschumacher.bsky.social · May 21

Great Minerva workshop on Biology of Healthy Aging by BIU and @cecad.bsky.social with Keynotes by Jan Hoeijmakers, Rafa de Cabo, @nirbarzilaimd.bsky.social and @garinis.bsky.social and the Cohen, @spanier55.bsky.social, @beyerlab.bsky.social, @eitanokun.bsky.social, Korenblit, Moran labs

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Andreas Beyer Group @beyerlab.bsky.social · May 22

Hurray!!!!! @cecad.bsky.social got another round of funding! Thanks to everyone involved and especially to Carien Niessen!

Universität zu Köln @unicologne.bsky.social · May 22

🎉Celebrating five Clusters of Excellence!
Congratulations to our Clusters: @cecad.bsky.social for aging research🧬, @ceplas.bsky.social for plant sciences🌱, @econtribute.bsky.social for economics, ML4Q for quantum research⚛️ and 🆕DYNAVERSE for astrophysics🌌

Read more ➡️https://uni.koeln/2AKU3

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Andreas Beyer Group @beyerlab.bsky.social · May 16

I highly recommend reading this.

Christian Frezza @frezzalab.bsky.social · May 9

I'd like to share this short piece on a topic I hope you will find useful. It is the result of a personl journey and many discussions with friends and peers. Let me know your thoughts.

network.febs.org/posts/the-pr...

The Professional Self: The Enemy Inside

network.febs.org

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