Christian Baumann
@cjbaumann.bsky.social
520 followers 640 following 14 posts
Postdoc in the Fasshauer lab at the University of Lausanne. Computational biology, protein evolution, membrane proteins & NMR.
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odedrechavi.bsky.social
Fwd: Fwd: “I hope this email finds you well”
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dhrebik.bsky.social
This comic is becoming increasingly realistic.
m.xkcd.com/3056/
Reposted by Christian Baumann
computingcaitie.bsky.social
I am excited to share our new preprint on the CAGE complex, a mysterious hollow protein complex that I first saw years ago while surveying Tetrahymena ciliary lysate www.biorxiv.org/content/10.1... #cilia #protistsonsky 🧬🧪
cjbaumann.bsky.social
Getting closer to the year 3000
Reposted by Christian Baumann
samhenrigold.hachyderm.io.ap.brid.gy
Did you know your MacBook has a sensor that knows the exact angle of the screen hinge?

It’s not exposed as a public API, but I figured out a way to read it and make it sound like an old wooden door.

Source code and a downloadable app to try it yourself […]

[Original post on hachyderm.io]
Reposted by Christian Baumann
labvanni.bsky.social
Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social.
How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)
Reposted by Christian Baumann
errantscience.com
The peer review process is a flawless system that has no issues whatsoever /s
Reposted by Christian Baumann
sokrypton.org
Made an attempt at generating a video of protein unfolding with #veo3 😹
Reposted by Christian Baumann
Reposted by Christian Baumann
meowmuir.bsky.social
#lipidtime The proteolipid code is the ultimate membrane model. It accommodates all observations while also being a falsifiable scientific theory that rejects the status quo (lipid rafts, picket fences, etc.)
doi.org/10.1186/s129...
Please read it.
Membranes are functionalized by a proteolipid code - BMC Biology
Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones...
doi.org
cjbaumann.bsky.social
I wasn’t aware of this. The concept sounds really cool. I like how it gives proteins a more active role in membrane formation. I’ll have to take a closer look with a fresh mind.
cjbaumann.bsky.social
For everyone interested in how membrane thickness differs between and within organelles, by @deglushk.bsky.social, S. Böhm & M. Beck: www.biorxiv.org/content/10.1...
www.biorxiv.org
Reposted by Christian Baumann
parafilmm.bsky.social
At times like these it's important to remember the 3 branches of science
The side of a box of Parafilm that features the flask, dish, and beaker. Text has been added under them. The flask is labelled chemistry, the dish biology, and the beaker jam making. Jam making is written in a different handwritten font
Reposted by Christian Baumann
annamazz.bsky.social
It’s Mary Anning’s birthday, so time to share @katebeaton.bsky.social’s brilliant cartoon again.
cjbaumann.bsky.social
Huge congrats to the authors for pulling this off:

Activation dynamics traced through a G protein–coupled receptor by 81 1H-15N NMR probes | Science www.science.org/doi/full/10....
www.science.org
cjbaumann.bsky.social
After years, I finally read this great paper on what the success of trial-and-error methods and AI tells us about emergent properties and reductionism in bio sciences: rdcu.be/emtBS
Irrational methods suggest indecomposability and emergence
rdcu.be
Reposted by Christian Baumann
david-grimm.bsky.social
"Dolphins call each other’s signature whistles if they get separated. Once, we played one of those whistles while the pair was still together. They responded with a totally different whistle. We call it the 'WTF whistle,' because it really did seem like that’s what they were asking." @science.org
‘About as close to aliens as we’ll ever get.’ Can AI crack animal language?
Dolittle Prize recognizes breakthroughs in translating “speech” of dolphins, cuttlefish, and other creatures
www.science.org
Reposted by Christian Baumann
yiweichang.bsky.social
...and big thanks to @jiwasa.bsky.social for making this amazing video to illustrate the strand-sliding mechanism!
Reposted by Christian Baumann
nadlerlab.bsky.social
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...
Reposted by Christian Baumann
ryoharada.bsky.social
New paper out!
We discovered a tiny archaeon with the smallest known archaeal genome — only 238 kbp!
Candidatus Sukunaarchaeum mirabile has almost no recognizable metabolic pathways and may rely heavily on a host to survive.
It also represents a novel, deep-branching lineage in the archaeal tree.
biorxiv-evobio.bsky.social
A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome https://www.biorxiv.org/content/10.1101/2025.05.02.651781v1