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Reposted by Daniel Arango

Ryan Flynn @raflynn5.bsky.social · Aug 6

RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

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Daniel Arango @danyarango.bsky.social · Jun 19

Congratulations!

Fred Hutch @fredhutch.org · Jun 18

Congratulations to the eight recipients of the 2025 Dr. Eddie Méndez Scholar Award! This award recognizes outstanding early-career scientists from underrepresented backgrounds who are studying cancer, infectious diseases and basic sciences. Learn more: bit.ly/4jWvT8O

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Daniel Arango @danyarango.bsky.social · Jun 19

Thank you, Ahmad!

Daniel Arango @danyarango.bsky.social · Jun 18

*tough

Daniel Arango @danyarango.bsky.social · Jun 18

Excited to share this preprint from my lab. We report a potent and site-specific inhibition of translation initiation by 2’O methylation.

It’s been a though year, but these discoveries keep us excited and motivated! #RNAsky #RNAbiology

bioRxiv Molecular Biology @biorxiv-molbio.bsky.social · Jun 17

Targeted Inhibition of Translation Initiation via 2'O-Methylation of Start Codons https://www.biorxiv.org/content/10.1101/2025.06.14.659565v1

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Reposted by Daniel Arango

Jeremy Berg @jeremymberg.bsky.social · Jun 15

New Wall Street Journal about Northwestern and the funding freeze.

[Gift link]

www.wsj.com/us-news/educ...

1/n

How Trump Blew Up Northwestern’s Business Model

The federal government froze the university’s research funding. It hasn’t offered the school a way to get it back.

www.wsj.com

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Daniel Arango @danyarango.bsky.social · Jun 10

👏

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · Jun 10

Seems a good time to invite Sen Britt to watch an NIH review panel (aka study section) analyze piles of grants over several days to identify the <10% that win funding. Applications that scientists spent months preparing, whose peers spent weeks poring through in advance of review mtg at NIH.

Max Kozlov @maxkozlov.bsky.social · Jun 10

Republican Senator Katie Britt: We need to create a system "where the beat idea wins... This is our opportunity to make a dollar go further and to make it have a greater impact."

(NIH already generates $2.56 for every $1 spent it spends on research.)

Daniel Arango @danyarango.bsky.social · Jun 10

👏

Senator Patty Murray @murray.senate.gov · Jun 10

My message to Trump’s NIH Director? No one in America wants us to do LESS cancer research.

No one is asking Trump to make it harder to cure Alzheimer's disease.

Yet Trump is cutting all of this NOW and demanding an $18 BILLION cut to NIH next year. Not on my watch.

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Reposted by Daniel Arango

Frances Yap @ribo1214.bsky.social · Jun 7

@thedailynu.bsky.social Northwestern is still supporting our research despite not receiving any $ from active and new fundable grants. Definitely unsustainable and anxieties are piling up..

Jeremy Berg @jeremymberg.bsky.social · Jun 7

Funding freeze at Northwestern from Emma Mairson at
grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis.

Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long.

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Reposted by Daniel Arango

Jeremy Berg @jeremymberg.bsky.social · Jun 7

Funding freeze at Northwestern from Emma Mairson at
grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis.

Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long.

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Reposted by Daniel Arango

@LaBonneLaB @labonnelab.bsky.social · Jun 7

I helped explain to the Chicago Tribune the enourmous and irrational damage the NIH funding freeze is causing at Northwestern. “You’re at risk of losing an entire next generation of scientists" "it’s terrifying; it’s completely senseless." www.chicagotribune.com/2025/06/07/w...

Worried Northwestern lab directors describe ‘bleak’ atmosphere in wake of Trump research funding freeze

The Trump administration’s freezing of $790 million in federal research funding for Northwestern University has left concerned lab directors without key grants and forced the university to spend mi…

www.chicagotribune.com

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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · Jun 7

Keep in mind: these are AWARDED grants, with Notice of Awards. The federal government is not honoring existing contracts with this university, refusing to reimburse for costs charge on awarded grants.

Jeremy Berg @jeremymberg.bsky.social · Jun 7

Funding freeze at Northwestern from Emma Mairson at
grant-watch.us. Data from USAspending. Normally, ~$70 M per month. Now, bupkis.

Northwestern is keeping research moving and must be spending ~$40 M per month. Clearly not sustainable for too long.

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Reposted by Daniel Arango

WTTW - Chicago PBS @wttw.bsky.social · Apr 25

Professors and researchers at Chicago-area universities said federal funding cuts are leaving research projects unfinished.

Julius Lucks, a chemical engineering professor at Northwestern, speaks on if another sector could fund university research.

to.wttw.com/3Ygl3T8

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Reposted by Daniel Arango

DjuranovicLab at Brown University RNA Center @djuranoviclab.bsky.social · Apr 14

Ready for the next RNA session in @asbmb.bsky.social meeting. We start soon...

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Daniel Arango @danyarango.bsky.social · Apr 10

Happened to me too

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Joana Vidigal @vidigaljoana.bsky.social · Apr 3

In the midst of everything it feels particularly appropriate to highlight all the amazing #RNA research taking place at #NIH!

Follow this thread to join us for our biannual #RNASymposium, this year featuring intramural research superstars!

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Josh Mendell @mendell-lab.bsky.social · Apr 3

It's difficult to focus on science with everything going on, but I still enjoy hearing about other people's work here, so I want to continue sharing ours. Congrats to postdoc Jong-Sun Lee for his outstanding work published in @cp-molcell.bsky.social! Details in thread👇
www.cell.com/molecular-ce...

An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation

Cancer cells frequently enhance ribosome production to support rapid growth. Here, Lee et al. demonstrate that an isoform of lncRNA CRNDE containing an ultraconserved element (CRNDEUCE) promotes 60S r...

www.cell.com

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Reposted by Daniel Arango

Chrystal Starbird @drstarbird.bsky.social · Apr 2

Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.

Letter from the NIH indicating that my grant has been terminated (though it seems we can keep the remaining funds for this year?)

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Vijay G. Sankaran @bloodgenes.bsky.social · Mar 27

So proud of this incredible work from @g-agarwal.bsky.social from our group with help from many fantastic folks in our lab and inspiring collaborators, including @kharaslab.bsky.social, Alex Bick, @yashpershad.bsky.social, and many others! Please check out Gaurav's awesome 🧵👇👇

Gaurav Agarwal @g-agarwal.bsky.social · Mar 27

What protects individuals from developing blood cancers?

Thrilled to share my work in @bloodgenes.bsky.social lab, describing inherited resilience protecting blood stem cells from clonal hematopoiesis by modifying RNA regulation. 🧵👇 (1/n)
www.biorxiv.org/content/10.1...

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Reposted by Daniel Arango

Gabriel Rocklin @grocklin.bsky.social · Mar 26

Small proteins can be more complex than they look!

We know proteins fluctuate between different conformations- but by how much? How does it vary from protein to protein? Can highly stable domains have low stability segments? @ajrferrari.bsky.social experimentally tested >5,000 domains to find out!

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Kelton Minor @keltonminor.bsky.social · Mar 18

There are days in life that shake you.

I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵

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Tina Termini @cterminiphd.bsky.social · Mar 7

We were delighted to have @king5news.com.web.brid.gy visit us in the Termini Lab to discuss how NIH funding cuts could affect cancer research:

m.youtube.com/watch?v=Szo9...

We NEED indirect costs to provide funding needed complete research studies that will lead to life saving discoveries.

Potential NIH funding cuts could affect local cancer research

YouTube video by KING 5 Seattle

m.youtube.com

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Denis Wirtz @deniswirtz.bsky.social · Mar 13

NIH is the best investment there is.

www.forbes.com/sites/michae...

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

www.forbes.com

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American Association for Cancer Research (AACR) @theaacr.bsky.social · Feb 18

The AACR is deeply concerned that the Administration’s recent actions are threatening NIH and its mission to accelerate progress for patients with cancer and other diseases that afflict millions of Americans. Read our statement: https://buff.ly/4gRXNB8

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Molecular Cell @cp-molcell.bsky.social · Feb 12

Online Now: The integrated stress response regulates 18S nonfunctional rRNA decay in mammals

The integrated stress response regulates 18S nonfunctional rRNA decay in mammals

To maintain translational fidelity, cells degrade decoding-incompetent ribosomes through the 18S nonfunctional rRNA decay (NRD) pathway. Coria et al. demonstrate that the concerted actions of GCN2, RNF10, and RIOK3 lead to a block in translation…

dlvr.it

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