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Ebrahim Lab

@ebrahim-lab.bsky.social

110 followers 110 following 9 posts

Lab focused on molecular force-generators and -sensors in living tissues, and all things microscopy @UVA School of Medicine. https://med.virginia.edu/ebrahim-lab/

med.virginia.edu

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Reposted by Ebrahim Lab

Ahmad Jomaa @jomaalab.bsky.social · Aug 1

Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: www.biorxiv.org/content/10.1...

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Ebrahim Lab @ebrahim-lab.bsky.social · Jul 26

Having seen your bingo card, we had to make it happen 😉!

Thank you for highlighting our work @hankgreen.bsky.social ! 🙏🏽

Hank Green @hankgreen.bsky.social · Jul 25

THIS WAS LITERALLY ON MY BINGO CARD!!

Scientists discover unknown organelle inside our cells

Ebrahim Lab @ebrahim-lab.bsky.social · May 19

Thank you, Ilya! :)

Ebrahim Lab @ebrahim-lab.bsky.social · May 17

Proposed mechanism of MVB formation

Ebrahim Lab @ebrahim-lab.bsky.social · May 17

Early for #MicroscopyMonday: #Hemifusomes- Newly discovered ESCRT-independent intermediates of intraluminal vesicle and multivesicular body formation! In collaboration with the Kachar Lab at the NIH and out today in @natcomms.nature.com : rdcu.be/emtQu

#cryoET #trafficking #organelle #hemifusion

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Ebrahim Lab @ebrahim-lab.bsky.social · May 6

😞

Ebrahim Lab @ebrahim-lab.bsky.social · May 2

"Stereocilia"- actin-based skyscrapers that adorn sensory cells of our inner ear and covert vibrations into electrical signals—the first step in hearing and balance. #FluorescenceFriday

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Reposted by Ebrahim Lab

Shashank Shekhar lab @sshekhr.bsky.social · Apr 26

🎉🎉We’re on the cover of Nature Physics! @natphys.nature.com

Here is the original paper www.nature.com/articles/s41...

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Ebrahim Lab @ebrahim-lab.bsky.social · Apr 25

From stem cell to structure-
This human colonoid shows the self-organization of intestinal epithelial cells in 3D—nuclei in magenta, actin in green. A living miniature gut for your #FluorescenceFriday.

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Reposted by Ebrahim Lab

Thibaut Brunet @thibautbrunet.bsky.social · Apr 22

A dream come true: the first expansion microscopy images of C. flexa 🤩 Generated by Mylan & Uzuki who learned from the best (@hiralshah.bsky.social @gautamdey.bsky.social @dudinlab.bsky.social). We will learn so much from these!

Expansion microscopy micrograph of the choanoflagellate Choanoeca flexa, vaguely evocative of a cactus. Red = tubulin, green = actin, blue = DNA

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Reposted by Ebrahim Lab

Mark Peifer (He, him) @peiferlabunc.bsky.social · Apr 21

Only 29 slots left out of 200--register now!

Mark Peifer (He, him) @peiferlabunc.bsky.social · Dec 18

Cell and developmental biologists: as you start looking at conferences in 2025, consider joining us at the 2025 Cell Contact & Adhesion GRC. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost
www.grc.org/cell-contact...

Poster for the meeting including speaker list and location

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Ebrahim Lab @ebrahim-lab.bsky.social · Apr 18

🧫 A gentle reminder that your gut is an actual work of art.
#FluorescenceFriday #BeneathTheScope

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Reposted by Ebrahim Lab

Elias Spiliotis @septinlab.bsky.social · Apr 16

Two months left for FASEB Conference - Septins: Spatial regulators of cell biology
Register now:
events.faseb.org/event/septin...
Come find out what these filaments do at the interface of the actin and microtubule cytoskeletons and cell membranes. You'll be hooked for life.

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Reposted by Ebrahim Lab

@PoratShliomLab @poratshliomlab.bsky.social · Apr 14

Is liver zonation conserved from mice to humans? And how does fibrosis affect zonation in patients? Now, these questions are answered using scDVP. Some collaborations are meant to be! @carolineweiss.bsky.social@frosenberger.bsky.social @mannlab.bsky.social@mlsb-borgwardt.bsky.social

Mann Lab @mannlab.bsky.social · Apr 14

Introducing our single-cell DVP framework combining strategic cell selection with protein gradient mapping algorithms. Analyzing hepatocyte proteomes across 18 human livers, revealing cross-species differences, and mapping disruptions in liver fibrosis.
www.biorxiv.org/content/10.1...

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Reposted by Ebrahim Lab

Dominik Robak @dominikrobak.bsky.social · Apr 14

#MicroscopyMonday | Colon-scoping turned coral reef

Was imaging the colon when I accidentally stumbled into this glowing patch of vascularized white adipose tissue.

🔵 mT/mG mouse (mT-only) → red membranes shown in cyan

Accidental imaging hits different.

#IntravitalImaging #LiveImaging

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Reposted by Ebrahim Lab

Sergio Cruz-León @sergiocruzleon.bsky.social · Apr 11

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social

🔗 Preprint here tinyurl.com/3a74uanv

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Reposted by Ebrahim Lab

Dominik Robak @dominikrobak.bsky.social · Apr 11

#3DThursday | Intestinal villi in all their folded glory

These self-renewing, nutrient-absorbing structures are beautiful and functional.

🔴 Phalloidin
🔵 DAPI
🟢 Clvd cas-3 (extrusion in action!)

Fixed tissue 3D imaging = big insight, tiny resolution.
#Microscopy #3DImaging #biophysics #intestine

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Ebrahim Lab @ebrahim-lab.bsky.social · Apr 8

Have cutting-edge cell biology research to share? Submit to Molecular Biology of the Cell (MBoC)- dedicated to advancing discovery and fostering collaboration.

Proud to be part of the editorial team supporting groundbreaking science. molbiolcell.org

#CellBiology #MBoC #Research

Molecular Biology of the Cell (MBoC)

molbiolcell.org