@gordonwells.bsky.social
Reposted
We used to do real science
January 12, 2026 at 1:59 AM
We used to do real science
Reposted
i know we're all busy but i just overheard a plumber say "parlez-vous français ? non ? you motherfuckers don't even speak french, do you" to a pair of french bulldogs
January 8, 2026 at 2:18 PM
i know we're all busy but i just overheard a plumber say "parlez-vous français ? non ? you motherfuckers don't even speak french, do you" to a pair of french bulldogs
Not making any promises, but I'd like to meet her cat.
December 31, 2025 at 6:41 PM
Not making any promises, but I'd like to meet her cat.
Reposted
Me getting back to sending nagging emails on January 6th when people return to work from the Christmas break
December 31, 2025 at 11:32 AM
Me getting back to sending nagging emails on January 6th when people return to work from the Christmas break
Reposted
Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.
December 30, 2025 at 12:56 PM
Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.
Reposted
New post!
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
Medical breakthroughs in 2025
... and a happy new year.
www.scientificdiscovery.dev
December 28, 2025 at 6:37 PM
New post!
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
There was a lot of innovation in medicine and biomedical research this year, and I've tried to summarize the biggest ones in this blogpost.
Medical breakthroughs in 2025. Plus a serious note at the end.
www.scientificdiscovery.dev/p/medical-br...
I remember an SA ensconced German friend of the family saying "how can 22 grown men play a game for 5 days and it still ends up as a draw?". I miss those days. Death to Bazball.
Lunch here on day 3. Head and Labuschagne survive with relative ease, Carse and Archer not able to get a huge amount going
Not a bad session for England, but they need three or four more good ones in a row
Aus 17-1
youtube.com/live/UwOzROZ...
#Ashes #AUSvENG
Not a bad session for England, but they need three or four more good ones in a row
Aus 17-1
youtube.com/live/UwOzROZ...
#Ashes #AUSvENG
The Ashes, 3rd Test, day 3, Adelaide
YouTube video by Guerilla Cricket
youtube.com
December 19, 2025 at 1:54 AM
I remember an SA ensconced German friend of the family saying "how can 22 grown men play a game for 5 days and it still ends up as a draw?". I miss those days. Death to Bazball.
You're going to have to do episodes on Oliver Sacks and Twin Studies now, aren't you @stuartjritchie.bsky.social @tomchivers.bsky.social?
December 14, 2025 at 12:28 PM
You're going to have to do episodes on Oliver Sacks and Twin Studies now, aren't you @stuartjritchie.bsky.social @tomchivers.bsky.social?
Monaspace
An innovative superfamily of fonts for code
monaspace.githubnext.com
December 11, 2025 at 3:10 PM
Dare I say it, but I think we're gradually turning from chokers into stranglers.
I hope the WTC winnings get put to good use.
I hope the WTC winnings get put to good use.
If SA's first innings versus India lasts just 10 more overs, it will have persisted for the same number of overs (140) as the entire 1st Ashes Test in Perth.
December 3, 2025 at 9:34 PM
Dare I say it, but I think we're gradually turning from chokers into stranglers.
I hope the WTC winnings get put to good use.
I hope the WTC winnings get put to good use.
Reposted
If you treat a five day Test as a five-day match, you greatly diminish your likelihood of defeat.
November 23, 2025 at 10:51 AM
If you treat a five day Test as a five-day match, you greatly diminish your likelihood of defeat.
Reposted
To break the ice, I asked a biosecurity guy what his favourite bioweapon was, but he didn't find it amusing
December 3, 2025 at 8:36 AM
To break the ice, I asked a biosecurity guy what his favourite bioweapon was, but he didn't find it amusing
The evolution wars might come back.
Next, flat eathers at NASA and NOAA.
Next, flat eathers at NASA and NOAA.
New: HHS employees were asked Monday evening to fill out a survey (it's voluntary/not required) about any religious discrimination they have witnessed or experienced, in an attempt to comply with Trump's "Eradicating Anti-Christian Bias" executive order from early this year. So that's cool.
December 2, 2025 at 5:05 PM
The evolution wars might come back.
Next, flat eathers at NASA and NOAA.
Next, flat eathers at NASA and NOAA.
Reposted
For their research showing that rape is generally motivated by sexual desire, Randy Thornhill and Craig Palmer were subjected to death threats and hounded in their personal and professional lives. And yet, they were right.
The Unwelcome Truth about Rape
For their research showing that rape is generally motivated by sexual desire, Randy Thornhill and Craig Palmer were subjected to death threats and hounded in their personal and professional lives. And yet, they were right.
quillette.com
November 27, 2025 at 9:17 AM
For their research showing that rape is generally motivated by sexual desire, Randy Thornhill and Craig Palmer were subjected to death threats and hounded in their personal and professional lives. And yet, they were right.
Reposted
Great writeup from @startswithabang.bsky.social of an extraordinary hypothesis: the reason the two sides of the moon are so different might come down to tidal locking when the moon was still forming, and chemical gradients in the proto-lunar material due to radiant heat from the Earth!
The Moon's two faces don't match, and we think we know why
The far side of the Moon is incredibly different from the Earth-facing side. 66 years later, we know why the Moon's faces are not alike.
bigthink.com
December 1, 2025 at 8:34 AM
Great writeup from @startswithabang.bsky.social of an extraordinary hypothesis: the reason the two sides of the moon are so different might come down to tidal locking when the moon was still forming, and chemical gradients in the proto-lunar material due to radiant heat from the Earth!
Reposted
i’m so happy for him
November 26, 2025 at 10:48 PM
i’m so happy for him
Ah good, I have a drive to the Berg coming up this weekend.
Imagine you lived in the 18th century.
Smallpox kills 1 in 3 cases. Yet you can’t culture pathogens, don’t know germ theory, and have no idea what a virus is. How would you invent a vaccine?
In a new episode of HARD DRUGS, we trace the history of vaccines!
Smallpox kills 1 in 3 cases. Yet you can’t culture pathogens, don’t know germ theory, and have no idea what a virus is. How would you invent a vaccine?
In a new episode of HARD DRUGS, we trace the history of vaccines!
The history of vaccines
open.spotify.com
November 26, 2025 at 7:33 PM
Ah good, I have a drive to the Berg coming up this weekend.
While she was still foreign minister SA hosted the Sudanese RSF warlord. Let her be welcome there.
US revokes visa of former South African minister who initiated genocide case against Israel - https://www.middleeasteye.net/news/us-revokes-visa-south-africa-naledi-pandor-led-case-icj-israel-genocide
US revokes visa of former South African minister who initiated genocide case against Israel
Naledi Pandor played a key role in South Africa's case against Israel at the International Court of Justice
www.middleeasteye.net
November 23, 2025 at 6:22 PM
While she was still foreign minister SA hosted the Sudanese RSF warlord. Let her be welcome there.
Reposted
You will never in a million years guess to whom this post is referring
The damned in hell are not more powerful for the fact that the fires do not consume them; it is part and parcel of their torment.
November 23, 2025 at 4:08 PM
You will never in a million years guess to whom this post is referring
Reposted
Home Alone, 1990. Dir. Werner Herzog
November 23, 2025 at 2:42 PM
Home Alone, 1990. Dir. Werner Herzog
Reposted
A new special issue of Philosophical Transactions B takes on one of science’s biggest questions: how life begins.
Rather than retracing Earth’s history, the authors look for the universal conditions that could make life possible anywhere, approaching the question from many fields and angles.
Rather than retracing Earth’s history, the authors look for the universal conditions that could make life possible anywhere, approaching the question from many fields and angles.
How life begins and where it might happen again
A recent special issue of Philosophical Transactions B takes on one of the biggest mysteries in science: how life first began. Instead of trying to replay Earth’s exact history, the issue’s authors lo...
www.santafe.edu
November 21, 2025 at 6:03 PM
A new special issue of Philosophical Transactions B takes on one of science’s biggest questions: how life begins.
Rather than retracing Earth’s history, the authors look for the universal conditions that could make life possible anywhere, approaching the question from many fields and angles.
Rather than retracing Earth’s history, the authors look for the universal conditions that could make life possible anywhere, approaching the question from many fields and angles.
Reposted
Guidelines for T cell nomenclature
In the 1960s, lymphocytes were first parsed into two subsets, B cells and T cells. This was not without controversy; it was initially noted publicly that B and T were the first and last letters of ‘bullshit’
www.nature.com/artic...
In the 1960s, lymphocytes were first parsed into two subsets, B cells and T cells. This was not without controversy; it was initially noted publicly that B and T were the first and last letters of ‘bullshit’
www.nature.com/artic...
Guidelines for T cell nomenclature
Nature Reviews Immunology - This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomenclature that is designed to...
www.nature.com
November 19, 2025 at 6:06 PM
Guidelines for T cell nomenclature
In the 1960s, lymphocytes were first parsed into two subsets, B cells and T cells. This was not without controversy; it was initially noted publicly that B and T were the first and last letters of ‘bullshit’
www.nature.com/artic...
In the 1960s, lymphocytes were first parsed into two subsets, B cells and T cells. This was not without controversy; it was initially noted publicly that B and T were the first and last letters of ‘bullshit’
www.nature.com/artic...
Upgrading conda is starting to give me gentoo flashbacks
November 19, 2025 at 10:28 PM
Upgrading conda is starting to give me gentoo flashbacks
Motte and bailey games. If you want to address health disparities don't poison science and medicne with identity politics and pomo BS.
Thoughtful piece on the importance of "DEI" in health research, published in Time Magazine.
time.com/7333975/dei-...
This presents the case in the context of lupus.
time.com/7333975/dei-...
This presents the case in the context of lupus.
DEI Isn’t Wasteful. It’s Necessary for Good Medicine
Lupus patients pay the price when we erase inclusion from medical research.
time.com
November 19, 2025 at 6:16 PM
Motte and bailey games. If you want to address health disparities don't poison science and medicne with identity politics and pomo BS.