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Sandra Hake @hake-chromatin.bsky.social · 1d

Extremely proud of my PhD student Lena Paasche, who won the prize for the best short-talk at the @gfgenetik.bsky.social symposium on "Epigenetics & Chromatin"! She is amazing: as scientist and as a wonderful and empathic person!

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Sandra Hake @hake-chromatin.bsky.social · 6d

Thank you! You are a wonderful person and an amazing scientist. I am glad that I met you at the symposium! All the best for your research!

Reposted by Sandra Hake

Valentin Flury @flurylab.bsky.social · 10d

It has been a lot of fun to present our research focus and get to know the @gfgenetik.bsky.social! Thank you so much for having me and organising this great symposium! Looking forward to the next one!

Gesellschaft für Genetik @gfgenetik.bsky.social · 12d

Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm.

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Sandra Hake @hake-chromatin.bsky.social · 10d

Congratulations! Amazing story!

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Reposted by Sandra Hake

The Braun Lab @thebraunlab.bsky.social · 11d

This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1....
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.

Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin

Subtelomeres are imperfect repeats adjacent to telomeres that are repressed by heterochromatin. Although essential for genome integrity, their repetitive nature has thwarted dissection of local hetero...

www.biorxiv.org

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Reposted by Sandra Hake

Mark Hartmann @mphartmann.bsky.social · 12d

Pioneers of Epigenetics honored: Davor Solter & Azim Surani receive the 2026 Paul Ehrlich & Ludwig Darmstaedter Prize. Their discovery of genomic imprinting revealed why mammals need both parents—opening the field of epigenetics.

#Epigenetics #GenomicImprinting #PaulEhrlichPrize #CanSky #Science

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Reposted by Sandra Hake

Gesellschaft für Genetik @gfgenetik.bsky.social · 12d

It was an awesome meeting! Fruitful discussion and lots of networking. Thanks to all attendees! More fotos will follow soon.

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Reposted by Sandra Hake

Akis (Argyris) Papantonis @akispapantonis.bsky.social · 13d

Just half a day in and it’s been a blast, with really incredible talks here on Giessen!

Gesellschaft für Genetik @gfgenetik.bsky.social · 14d

What a great first day at the GfG symposium on epigenetics & chromatin. Fantastic talks by @akispapantonis.bsky.social , @apombo1.bsky.social, @marcusbuschbeck.bsky.social and Philipp Korber. And Peter Becker giving the Max-Delbrueck lecture. A real treat for the audience!

Juri Kazakevych @juri-epigenomics.bsky.social · 14d

Looking forward to exciting talks at the GfG Symposium in Gießen.

Already found a poster, featuring my favourite gene: SMARCAD1, by Jacqueline Mermoud

#epigenomics @diagenode.bsky.social @gfgenetik.bsky.social

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Reposted by Sandra Hake

Gesellschaft für Genetik @gfgenetik.bsky.social · 12d

Amazing 2. day at the GfG ‘Epigenetics & Chromatin’ symposium. Fantastic flash talks, a great first poster session and many memorable talks: among others @erhardtlab.bsky.social, @rodvilla.bsky.social, @thebraunlab.bsky.social, @flurylab.bsky.social, Ehrenhofer-Murray, Liefke, Heun, Imhof & Brehm.

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Reposted by Sandra Hake

Gesellschaft für Genetik @gfgenetik.bsky.social · 14d

What a great first day at the GfG symposium on epigenetics & chromatin. Fantastic talks by @akispapantonis.bsky.social , @apombo1.bsky.social, @marcusbuschbeck.bsky.social and Philipp Korber. And Peter Becker giving the Max-Delbrueck lecture. A real treat for the audience!

Juri Kazakevych @juri-epigenomics.bsky.social · 14d

Looking forward to exciting talks at the GfG Symposium in Gießen.

Already found a poster, featuring my favourite gene: SMARCAD1, by Jacqueline Mermoud

#epigenomics @diagenode.bsky.social @gfgenetik.bsky.social

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Reposted by Sandra Hake

Juri Kazakevych @juri-epigenomics.bsky.social · 14d

Looking forward to exciting talks at the GfG Symposium in Gießen.

Already found a poster, featuring my favourite gene: SMARCAD1, by Jacqueline Mermoud

#epigenomics @diagenode.bsky.social @gfgenetik.bsky.social

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Reposted by Sandra Hake

Tobias Warnecke @tobiaswarnecke.bsky.social · Sep 8

Please re-post:

Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...

Abstract deadline: 30 September

EvoChromo: Evolutionary approaches to research in chromatin

Chromatin is the complex of DNA, RNA and protein that is found making up the chromosomes in eukaryotic cells. Chromatin is essential for proper genome function and is involved in chromosome segregati…

meetings.embo.org

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Sandra Hake @hake-chromatin.bsky.social · Sep 5

Happy Birthday!! Many „accepted“ notifications for you!

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Sandra Hake @hake-chromatin.bsky.social · Sep 4

Congratulations!!! Fantastic news!

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Reposted by Sandra Hake

dfachinetti.bsky.social @dfachinetti.bsky.social · Sep 4

#1 Centromeres are epigenetic loci defined by CENP-A, positioned in unmethylated DNA flanked by highly methylated regions. Our work, published in @natgenet.nature.com in collaboration with @naltemose.bsky.social investigates the role of DNAme at human centromeres www.nature.com/articles/s41...

DNA methylation influences human centromere positioning and function - Nature Genetics

Genome-wide and targeted perturbation of DNA methylation at centromeres affects CENP-A positioning and centromere structure, resulting in aneuploidy and reduced cell viability.

www.nature.com

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Reposted by Sandra Hake

Kurianlab @kurianlab.bsky.social · Sep 4

Useful data set:
www.nature.com/articles/s41...

Morphological map of under- and overexpression of genes in human cells - Nature Methods

This Resource presents the genetic subset of the 136,000 chemical and genetic perturbations tested by the Joint Undertaking for Morphological Profiling (JUMP) Cell Painting Consortium and associated a...

www.nature.com

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Reposted by Sandra Hake

Jack Bateman @jbateman01.bsky.social · Sep 3

What makes genes burst www.cell.com/trends/cell-...

What makes genes burst

Genes burst. Instead of being monotonously transcribed by a steady stream of RNA polymerases, active genes undergo transient and random pulses of transcription that are referred to as gene bursting. T...

www.cell.com

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Reposted by Sandra Hake

Kaia Mattioli @kaiamattioli.bsky.social · Sep 3

out today: my labmate Shubham developed a super clever new technique to profile TF-DNA interactions with unprecedented resolution of low-affinity binding sites, revealing patterns in how these sites are organized in the genome to modulate TF occupancy:

www.nature.com/articles/s41...

Multiple overlapping binding sites determine transcription factor occupancy - Nature

A new method enables comprehensive screening and identification of low-affinity DNA binding sites for transcription factors, and reveals that nucleotides flanking high-affinity binding sites create ov...

www.nature.com

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Reposted by Sandra Hake

Rahul K @theresearch.bsky.social · Sep 3

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Reposted by Sandra Hake

FMI science @fmiscience.bsky.social · Sep 2

In a new study, FMI researchers show that two enzymes—KDM2A and KDM2B—act as safeguards in eggs, preventing excessive DNA methylation at gene regions. Without them, abnormal methylation is passed to embryos, repressing genes needed for early development. www.cell.com/developmenta...

Preventing CpG hypermethylation in oocytes safeguards mouse development

Kawamura et al. show that H3K36me2 removal by the KDM2A and KDM2B histone demethylases restricts DNMT3A in establishing global DNA methylation in oocytes. Maternal Kdm2a/Kdm2b knockout embryos die dur...

www.cell.com

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Reposted by Sandra Hake

Sean Flynn @seanflynn.bsky.social · Sep 2

Please share!
PhD projects available through @gw4biomeddtp.bsky.social
Please get in touch if you are interested in studying chromatin biology in stem cell models

gw4biomed.ac.uk/architects-o...

gw4biomed.ac.uk/risk-vs-prot...

gw4biomed.ac.uk/rna-dependen...

gw4biomed.ac.uk/investigatin...

Architects of the Genome: Using genomic technologies to elucidate the role of CTCF in neurodevelopmental disorders - GW4 BioMed MRC DTP

Project Code MRCNMH26Ex Flynn Project Type The project is primarily wet-lab based, with a dry-lab component in Years 2 and 3. Research Theme Neuroscience and Mental Health Project Summary Download Sum...

gw4biomed.ac.uk

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Reposted by Sandra Hake

FragileNucleosome @fnucleosome.bsky.social · Sep 1

We're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social!

register here for the entire series: us06web.zoom.us/webinar/regi...

Fragile Nucleosome Fall Seminars:
September 10 Grace Bower, Kvon Lab @ UC Irvine, USA
Jennifer Phillips-Cremins, UPenn, USA

September 24 Ali Wilkening, Sanulli Lab @ Stanford, USA
Juanma Schvartzman, Columbia University, USA

October 8 Sanim Rahman, Greenberg Lab @ UPenn, USA
Alex Federation, Talus Bio, USA

October 22 Alice Laigle, Croll Lab @ University of Neuchâtel, Switzerland
Seungsoo Kim, UC Irvine, USA

November 5 Hannah Long, University of Edinburgh, UK
Jeff Vierstra, Altius Institute, USA

November 19 Ishtiaque Hossain, Pastor Lab @ McGill, Canada
Sarah Teichmann, University of Cambridge, UK

December 3 María Mariner Faulí, Rada Iglesias Lab @ IBBTEC, Spain
Jonathan Henninger, Carnegie Mellon, USA

December 17 Rebecca Berrens, Oxford University, UK
Jean-Benoit Lalanne, University of Montreal, Canada

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Reposted by Sandra Hake

Tobias Warnecke @tobiaswarnecke.bsky.social · Sep 1

Please re-post: If you know (or are!) somebody who might fancy doing a PhD (Oct 2026 start) in my group @oxfordbiochemistry.bsky.social, working on chromatin evolution in prokaryotes (or other things we're interested in), please have a look at www.bioch.ox.ac.uk/supervisors-...

Supervisors and Projects

www.bioch.ox.ac.uk

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Reposted by Sandra Hake

Graham Dellaire @docdellaire.bsky.social · Sep 1

Two new druggable targets in ERG-driven prostate cancer - KMT2A and DOT1L www.nature.com/articles/s41...

ERG-driven prostate cancer initiation is cell-context dependent and requires KMT2A and DOT1L - Nature Genetics

Lineage tracing in mice identifies a subpopulation of basal cells that express Tmprss2 and Nkx3 as the origin of ERG-driven prostate cancer. Upon expansion, these cells show an enrichment for STAT3 ch...

www.nature.com

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Sandra Hake @hake-chromatin.bsky.social · Aug 29

Would be nice to be added to the list! Thanks!

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