Lightnews — Scholar-powered news

Joost Snijder @joostsnijder.bsky.social · 11h

Congrats!

Reposted by Joost Snijder

C&EN (Chemical & Engineering News) @cenmag.bsky.social · 23h

The 2025 #NobelPrize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal–organic frameworks.” Stay tuned for the full story to come! cen.acs.org/people/nobel...

#ChemNobel #Chem #Chemistry #chemsky 🧪

The 2025 chemistry Nobel goes to MOFs

Susumu Kitagawa, Richard Robson and Omar M. Yaghi win the prize for developing metal–organic frameworks

cen.acs.org

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Reposted by Joost Snijder

Derek Lowe @dereklowe.bsky.social · 21h

A Chemistry Nobel that many had anticipated: metal-organic frameworks! Writeup coming on the blog later this morning:

Nobel Prize in Chemistry 2025

The Nobel Prize in Chemistry 2025 was awarded jointly to Susumu Kitagawa, Richard Robson and Omar M. Yaghi "for the development of metal–organic frameworks"

www.nobelprize.org

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Reposted by Joost Snijder

Lukas Käll @lukaskall.bsky.social · 21h

There is a position open in our lab, within this network. Our project deals with assessing identification and quantification errors for MS-based proteomics. www.protaiomics.eu/project/dc13...
Please check out all the project descriptions at the site below:

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Reposted by Joost Snijder

Briggs Group @briggsgroup.bsky.social · 2d

The mechanistic basis of cargo selection during Golgi maturation. From Rebecca Taylor, @katciazynska.bsky.social, @jggkaufman.bsky.social & @grigorytagiltsev.bsky.social at @mpibiochem.bsky.social with David Owen and Sean Munro's group @cellbiol-mrclmb.bsky.social | www.science.org/doi/10.1126/...

The mechanistic basis of cargo selection during Golgi maturation

Resident proteins of the Golgi recycle in vesicles and the protein GOLPH3 enables the COPI vesicle coat to accomplish this.

www.science.org

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Reposted by Joost Snijder

Peter Kwint @peterkwint.bsky.social · 1d

Echt jaloers op de factchecker die hier in mag duiken.

Jimmy Dijk @jimmydijk.sp.nl · 1d

Heb jij de quotes al gespot? 🦇

Kijk vanavond om 20:30 naar een buitengewoon gesprek op NPO 1

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Reposted by Joost Snijder

RCSB Protein Data Bank @rcsbpdb.bsky.social · 1d

The genome of ebola virus contains instructions for building seven proteins, which assemble with the genomic RNA to form one of the deadliest viruses.

PDB101: Molecule of the Month: Ebola Virus Proteins

Structures of ebola virus proteins are giving new hope for fighting this deadly virus

pdb101.rcsb.org

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Reposted by Joost Snijder

BK. Titanji @boghuma.bsky.social · 2d

A new Nature Medicine study analyzing health records from >100 million people in the US offers compelling evidence that reactivation of varicella-zoster virus (VZV) ,the same virus that causes chickenpox and shingles may contribute to dementia risk.
www.nature.com/articles/s41...

Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine

Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.

www.nature.com

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Reposted by Joost Snijder

RCSB Protein Data Bank @rcsbpdb.bsky.social · 2d

The bloodstream is filled with molecules and cells that search for invaders and destroy them if they are found. PDB structures have revealed how the immune system recognizes viruses and bacteria while leaving our normal molecules alone.
More at PDB-101:

PDB101: Browse: Immune System

PDB-101: Training, Outreach, and Education portal of RCSB PDB

pdb101.rcsb.org

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Reposted by Joost Snijder

Nature @nature.com · 2d

This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues

go.nature.com/3VNrH1s

Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

go.nature.com

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Reposted by Joost Snijder

The Daum Lab @daumlab.bsky.social · 2d

Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...

Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail

This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.

www.science.org

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Reposted by Joost Snijder

Roger Castells @rcastellsg.bsky.social · 3d

We’re looking for an enthusiastic postdoc to join our team. 😊

The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪

The position is fully funded for 3 years.

Please share 🙏

Job description and application details (deadline: October 11th): www.cnio.es/en/empleo/po...

Postdoctoral Research Assistant for the Biomolecular Design and Structural Nanomedicine Group

DescriptionWe are looking for a Postdoctoral Researcher to join Roger Castells-Graells’ lab at the Spanish National Cancer Research Centre (CNIO). The successful candidate will work on innovative biom...

www.cnio.es

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Reposted by Joost Snijder

Albert Heck @hecklab.bsky.social · 6d

Having a great time at msandm2025.org with a great bunch of people interesting in visualizing biomolecules, together with my co-chairs @joostsnijder.bsky.social @vixklen.bsky.social & Kyle Fort. Learning so much from all posters & lectures. We thanks all participants for joining us in Utrecht.

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Joost Snijder @joostsnijder.bsky.social · 8d

We’re hosting the MS+M conference in Utrecht today, lots of great talks ahead at the intersection of mass spec and microscopy. Here’s @hecklab.bsky.social kicking things off.

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Joost Snijder @joostsnijder.bsky.social · 8d

Congrats!

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Reposted by Joost Snijder

SBGrid Consortium @sbgrid.bsky.social · 8d

SBGrid's eLife paper received a citation in August from @joostsnijder.bsky.social from @utrechtuniversity.bsky.social in @pubs.acs.org Infectious Diseases.

Read more here: buff.ly/0VRRJZz

#SBGrid #StayConnected #ScienceMatters

Structural Basis for Postfusion-Specific Binding to the Respiratory Syncytial Virus F Protein by the Canonical Antigenic Site I Antibody 131–2a

The respiratory syncytial virus (RSV) fusion (F) protein is a major target of antiviral antibodies following natural infection or vaccination and is responsible for mediating fusion between the viral…

buff.ly

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Reposted by Joost Snijder

Lucas Farnung @lucas.farnunglab.com · 9d

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

Protein Domain Designer tool for the generation of publication-ready protein domain diagrams

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Reposted by Joost Snijder

Thelonevirologist @thelonevirologist.bsky.social · 12d

Epstein–Barr virus exploits desmocollin 2 as the principal epithelial cell entry receptor

www.nature.com/articles/s41...

Epstein–Barr virus exploits desmocollin 2 as the principal epithelial cell entry receptor - Nature Microbiology

A genome-wide CRISPR screen helps to identify the Epstein–Barr virus receptor desmocollin 2 for primary epithelial cell infection. Additional infection assays revealed that desmocollin 3 also aids infection.

www.nature.com

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Reposted by Joost Snijder

Ben Engel @cellarchlab.com · 13d

Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on!

#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵

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Reposted by Joost Snijder

Arc Institute @arcinstitute.org · 14d

In another preprint from the @brianhie.bsky.social Lab and @synbiogaolab.bsky.social, they introduce Germinal, a generative AI system for de novo antibody design.

Germinal produces functional nanobodies in just dozens of tests, making custom antibody design more accessible than ever before.

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Reposted by Joost Snijder

Arinjay Banerjee @banerjeelab.ca · 14d

www.nature.com/articles/s41...

Stunning work from the Chandran lab!

LRP8 is a receptor for tick-borne encephalitis virus - Nature

LRP8, an apolipoprotein E and reelin receptor with high expression in the brain, is a receptor for tick-borne encephalitis virus.

www.nature.com

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Reposted by Joost Snijder

Cody Hochstenbach @codyhochstenbach.bsky.social · 16d

De politiek zegt de volkshuisvesting in Nederland weer te willen versterken. Maar met de huidige plannen zal het aandeel sociale huurwoningen de komende jaren blijven krimpen.

Ik zette verschillende onderzoeksgegevens op een rijtje, Trouw schreef er een artikel over.

Een draadje:

Zelfs als álle regeringsplannen slagen, krimpt het aandeel sociale huurwoningen

De regering wil de komende jaren veel betaalbare huurwoningen laten bouwen. Maar zelfs als dat beleid goed wordt uitgevoerd, krimpt de sector.

www.trouw.nl

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Joost Snijder @joostsnijder.bsky.social · 17d

Exciting day. We’re rebooting our advanced proteomics course. Full house, Kelly about to kick things off!

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Reposted by Joost Snijder

Gagneur lab @gagneurlab.bsky.social · 21d

Excited to share Modanovo, our transformer-based method for de novo peptide sequencing, which supports a broad range of post-translational modifications (PTMs)!
www.biorxiv.org/content/10.1...
#proteomics #massspectrometry #PTM

Modanovo: A Unified Model for Post-Translational Modification-Aware de Novo Sequencing Using Experimental Spectra from In Vivo and Synthetic Peptides

Post-translational modifications (PTMs) play a central role in cellular regulation and are implicated in numerous diseases. Database searching remains the standard for identifying modified peptides fr...

www.biorxiv.org

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Reposted by Joost Snijder

James Lingford @jameslingford.bsky.social · 20d

RFdiffusion3 is here: www.biorxiv.org/content/10.1...

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