Katreya Lovrenert
@katreya.bsky.social
Computational Biology Manager for the Institute for Glial Sciences at Case Western Reserve University
Well shit. Now I want me some eels.
What should you do with your extra eels? Split them among your friends, yo!
In 973 Bishop Æthelwold gave 16k eels to Thorney Abbey & Peterborough Abbey: each monastery got 8,000 annually.
And sure...that seems like a lot. But its only about 22 eels a day! Not even one an hour!
🗃️🧪
In 973 Bishop Æthelwold gave 16k eels to Thorney Abbey & Peterborough Abbey: each monastery got 8,000 annually.
And sure...that seems like a lot. But its only about 22 eels a day! Not even one an hour!
🗃️🧪
December 30, 2025 at 9:29 PM
Well shit. Now I want me some eels.
Reposted by Katreya Lovrenert
This is the "SEA SHEEP" (Costasiella kuroshimae) & it took the old axiom: "you are what you eat" VERY literally.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
a close up of a green and white sponge with purple spots
Alt: A green and white sea sheep grazes on a green lawn of algae on a surface underwater.
media.tenor.com
December 27, 2025 at 5:02 PM
This is the "SEA SHEEP" (Costasiella kuroshimae) & it took the old axiom: "you are what you eat" VERY literally.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
Reposted by Katreya Lovrenert
“We must stop eating!” cried Toad as he ate another.
December 27, 2025 at 5:37 AM
“We must stop eating!” cried Toad as he ate another.
Reposted by Katreya Lovrenert
“Your windows need scrubbing,” said Frog. “Your plants need watering.”
“Tomorrow!” cried Toad. “I will do it all tomorrow!”
“Tomorrow!” cried Toad. “I will do it all tomorrow!”
December 26, 2025 at 11:37 AM
“Your windows need scrubbing,” said Frog. “Your plants need watering.”
“Tomorrow!” cried Toad. “I will do it all tomorrow!”
“Tomorrow!” cried Toad. “I will do it all tomorrow!”
Reposted by Katreya Lovrenert
Toad sat and did nothing. Frog sat with him.
December 21, 2025 at 11:37 PM
Toad sat and did nothing. Frog sat with him.
Reposted by Katreya Lovrenert
Here’s are lessons about reproducible research from my latest talk at Moderna:
divingintogeneticsandgenomics.com/post/repro-...
divingintogeneticsandgenomics.com/post/repro-...
Reproducible Computing in Bioinformatics: Lessons from My Latest Talk | Chatomics
Hey everyone, it’s Tommy here. If you’ve been following my blog or my Twitter/X (@tangming2005), you know I love diving into the practical side of bioinformatics and genomics.
Recently, I gave a talk titled “Good Enough Practices for Reproducible Computing” at Moderna, where I spent a good chunk of time chatting about reproducible computing.
Why? Because in our field, where data is exploding and analyses get complex, making sure your work can be repeated—by you or anyone else—is a game-changer.
divingintogeneticsandgenomics.com
December 21, 2025 at 2:15 PM
Here’s are lessons about reproducible research from my latest talk at Moderna:
divingintogeneticsandgenomics.com/post/repro-...
divingintogeneticsandgenomics.com/post/repro-...
Reposted by Katreya Lovrenert
AAAAAAAAAAHHHHHHHHHHHHHH
December 20, 2025 at 10:34 AM
AAAAAAAAAAHHHHHHHHHHHHHH
Reposted by Katreya Lovrenert
Psilocybin reshapes how the brain is connected. 🧠⚡️
Using viral tracing methods, the study found the psychedelic strengthens pathways related to sensory processing and weakened those tied to rumination.
@thetransmitter.bsky.social dives deeper into the study: https://bit.ly/4aD13AS
#neuroskyence
Using viral tracing methods, the study found the psychedelic strengthens pathways related to sensory processing and weakened those tied to rumination.
@thetransmitter.bsky.social dives deeper into the study: https://bit.ly/4aD13AS
#neuroskyence
December 9, 2025 at 5:00 PM
Psilocybin reshapes how the brain is connected. 🧠⚡️
Using viral tracing methods, the study found the psychedelic strengthens pathways related to sensory processing and weakened those tied to rumination.
@thetransmitter.bsky.social dives deeper into the study: https://bit.ly/4aD13AS
#neuroskyence
Using viral tracing methods, the study found the psychedelic strengthens pathways related to sensory processing and weakened those tied to rumination.
@thetransmitter.bsky.social dives deeper into the study: https://bit.ly/4aD13AS
#neuroskyence
Reposted by Katreya Lovrenert
tidyomics project 🔛 R-bloggers!
www.r-bloggers.com/2025/10/the-...
Thanks to @stemang.bsky.social, Maria Doyle @bioconductor.bsky.social, @jhsanchez.bsky.social, Mengyuan Shen, Jonathan Carroll and others in tidyomics for testing and getting this up and running
www.r-bloggers.com/2025/10/the-...
Thanks to @stemang.bsky.social, Maria Doyle @bioconductor.bsky.social, @jhsanchez.bsky.social, Mengyuan Shen, Jonathan Carroll and others in tidyomics for testing and getting this up and running
December 8, 2025 at 5:28 PM
tidyomics project 🔛 R-bloggers!
www.r-bloggers.com/2025/10/the-...
Thanks to @stemang.bsky.social, Maria Doyle @bioconductor.bsky.social, @jhsanchez.bsky.social, Mengyuan Shen, Jonathan Carroll and others in tidyomics for testing and getting this up and running
www.r-bloggers.com/2025/10/the-...
Thanks to @stemang.bsky.social, Maria Doyle @bioconductor.bsky.social, @jhsanchez.bsky.social, Mengyuan Shen, Jonathan Carroll and others in tidyomics for testing and getting this up and running
Reposted by Katreya Lovrenert
@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.
Multiscale structure of chromatin condensates explains phase separation and material properties
The structure and interaction networks of molecules within biomolecular condensates are poorly understood. Using cryo–electron tomography and molecular dynamics simulations, we elucidated the structur...
www.science.org
December 5, 2025 at 5:24 AM
@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.
Reposted by Katreya Lovrenert
you know how i know im a 44yo dad? how much i laughed at this shit
December 6, 2025 at 3:31 AM
you know how i know im a 44yo dad? how much i laughed at this shit
Reposted by Katreya Lovrenert
We got Weird Al out here singing Killing In The Name, the time for moderation is over
December 6, 2025 at 2:45 PM
We got Weird Al out here singing Killing In The Name, the time for moderation is over
Reposted by Katreya Lovrenert
AAAAAAAAAAAAAAAHHHHHHHHHHHHHH
December 5, 2025 at 12:47 AM
AAAAAAAAAAAAAAAHHHHHHHHHHHHHH
Reposted by Katreya Lovrenert
Reposted by Katreya Lovrenert
It's with heavy hearts that we share that Claude, our beloved albino alligator, has passed away at the age of 30. Claude brought joy to millions of people at the Academy and across the world during his 17 year tenure. We will miss him dearly. 🤍
December 2, 2025 at 10:22 PM
It's with heavy hearts that we share that Claude, our beloved albino alligator, has passed away at the age of 30. Claude brought joy to millions of people at the Academy and across the world during his 17 year tenure. We will miss him dearly. 🤍
Reposted by Katreya Lovrenert
We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen.
1/n
1/n
Intro to Bedder – The Quinlan Lab
quinlanlab.org
December 2, 2025 at 2:28 AM
Reposted by Katreya Lovrenert
Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
November 27, 2025 at 9:59 PM
Here is a copy of last year's Twitter thread explaining our preprint - jump to (21) for the new stuff 👀
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
Synergy between cis-regulatory elements can render cohesin dispensable for distal enhancer function
now revised and journal accepted at www.science.org/doi/10.1126/...
🧵👇
Reposted by Katreya Lovrenert
Bah, who needs cohesin if you're at the right place (near). Grover once taught us the difference between near and far (my favourite Sesame Street piece), and now amazing work from @elphegenoralab.bsky.social led by @karissalhansen.bsky.social shows us how: www.science.org/doi/10.1126/...
Synergy between regulatory elements can render cohesin dispensable for distal enhancer function
Enhancers are critical genetic elements controlling transcription from promoters, yet how they convey regulatory information across large genomic distances remains unclear. Here, we engineer pluripote...
www.science.org
November 27, 2025 at 7:10 PM
Bah, who needs cohesin if you're at the right place (near). Grover once taught us the difference between near and far (my favourite Sesame Street piece), and now amazing work from @elphegenoralab.bsky.social led by @karissalhansen.bsky.social shows us how: www.science.org/doi/10.1126/...
Reposted by Katreya Lovrenert
This is Bear. He is in charge of supervising Thanksgiving dinner preparation. Appointed himself to the role, but takes it very seriously. 14/10 (TT: emileebellant)
November 27, 2025 at 5:25 PM
This is Bear. He is in charge of supervising Thanksgiving dinner preparation. Appointed himself to the role, but takes it very seriously. 14/10 (TT: emileebellant)
Reposted by Katreya Lovrenert
Frog and Toad ate many cookies, one after another.
“You know, Toad,” said Frog, with his mouth full, “I think we should stop eating. We will soon be sick.”
“You are right,” said Toad. “Let us eat one last cookie, and then we will stop.”
“You know, Toad,” said Frog, with his mouth full, “I think we should stop eating. We will soon be sick.”
“You are right,” said Toad. “Let us eat one last cookie, and then we will stop.”
November 27, 2025 at 5:37 AM
Frog and Toad ate many cookies, one after another.
“You know, Toad,” said Frog, with his mouth full, “I think we should stop eating. We will soon be sick.”
“You are right,” said Toad. “Let us eat one last cookie, and then we will stop.”
“You know, Toad,” said Frog, with his mouth full, “I think we should stop eating. We will soon be sick.”
“You are right,” said Toad. “Let us eat one last cookie, and then we will stop.”
Reposted by Katreya Lovrenert
Reposted by Katreya Lovrenert
1/ Public datasets feel like a goldmine.
But look closer—there are landmines hidden inside.
Especially for single-cell RNA-seq.
A thread 🧵
But look closer—there are landmines hidden inside.
Especially for single-cell RNA-seq.
A thread 🧵
November 27, 2025 at 2:15 PM
1/ Public datasets feel like a goldmine.
But look closer—there are landmines hidden inside.
Especially for single-cell RNA-seq.
A thread 🧵
But look closer—there are landmines hidden inside.
Especially for single-cell RNA-seq.
A thread 🧵
Reposted by Katreya Lovrenert
1/ One of the biggest hidden killer in bioinformatics?
Not a bug. Not a crash.
It’s the 0-based vs 1-based coordinate trap.
A thread 🧵
Not a bug. Not a crash.
It’s the 0-based vs 1-based coordinate trap.
A thread 🧵
November 27, 2025 at 2:45 PM
1/ One of the biggest hidden killer in bioinformatics?
Not a bug. Not a crash.
It’s the 0-based vs 1-based coordinate trap.
A thread 🧵
Not a bug. Not a crash.
It’s the 0-based vs 1-based coordinate trap.
A thread 🧵
Reposted by Katreya Lovrenert
More detailed functional interrogation of enteric neuron subpopulations www.cell.com/cell/abstrac...
Properties and functions of transcriptionally distinct enteric neurons
Developing genetic access to transcriptionally distinct enteric neurons in vivo enables
the examination of morphological heterogeneity across cell types as well as cell-type-specific
influences on GI ...
www.cell.com
November 26, 2025 at 11:15 AM
More detailed functional interrogation of enteric neuron subpopulations www.cell.com/cell/abstrac...
Reposted by Katreya Lovrenert
We are excited to share our online book and preprint on “Orchestrating Spatial Transcriptomics Analysis with Bioconductor”!
Many people hours, calls and messages later: OSTA is now “in (pre)print”, though the real thing lives at bioconductor.org/books/OSTA.
Check it out, get in touch. We welcome any feedback, suggestions, wishes (& contributions).
It’s been a joy working with you @estellayixingdong.bsky.social!
Check it out, get in touch. We welcome any feedback, suggestions, wishes (& contributions).
It’s been a joy working with you @estellayixingdong.bsky.social!
November 22, 2025 at 12:38 PM
We are excited to share our online book and preprint on “Orchestrating Spatial Transcriptomics Analysis with Bioconductor”!