Casey Mahoney-Crane, Ph.D.
banner
mahoneykc.bsky.social
Casey Mahoney-Crane, Ph.D.
@mahoneykc.bsky.social
Neuroscientist/Postdoc in Mark Cookson’s lab/NIA studying LRRK2 in microglia
Ph.D. In Laura Volpicelli-Daley’s lab/UAB studied GBA1, synapses, & PD

Me a nerd? I think neuron to something!

views=mine
She/her👻
#neurospicy #firstgen #coffeeaddict #Dogmom
Reposted by Casey Mahoney-Crane, Ph.D.
New computational paper from the lab! Thanks to the reviewers for helping us improve this paper from the preprint version and Nucleic Acids Research for a smooth publication process.
Excited to share that our article on accurate sample deconvolution of pooled snRNA-seq data using sex-dependent gene expression patterns is live on NAR Genomics and Bioinformatics! 🎉

Check it out here: doi.org/10.1093/narg...

#NARGenomicsandBioinformatics #snRNAseq #Genomics #Bioinformatics
Validate User
doi.org
November 26, 2025 at 6:15 PM
Reposted by Casey Mahoney-Crane, Ph.D.
Researchers have developed polymeric nanocultures composed of iron-oxide nanoparticles, providing a field-ready approach for cultivating and studying environmental microbes under near-native conditions.

Learn more in this week’s issue of #ScienceAdvances: https://scim.ag/4r90UuS
November 21, 2025 at 10:50 PM
Inspiration is found everywhere
I recently rewatched Jurassic Park and was so excited to share this clip with my Genomics and Bioinformatics class to teach how critical it is to understand Unix/Linux after Lex saves everyone from the velociraptor by rebooting the security system! 😂🦖🦕👩🏼‍💻
November 6, 2025 at 12:45 AM
Day 14 of government shutdown: I think I’m starting to miss the NIH geese. I hope they’re doing well.
October 14, 2025 at 2:39 PM
While we cannot control the whirlwind around, I remain hopeful that justice, integrity, and truth will ultimately prevail.
September 9, 2025 at 1:30 PM
Great, bipartisan perspective on RFK’s comments
1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."

It's literally a vital feature of both science and of representative democracy.

I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.
RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’
HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.
www.scrippsnews.com
August 12, 2025 at 11:20 PM
Reposted by Casey Mahoney-Crane, Ph.D.
The mRNA vaccines were miraculous. It lost public trust because there was a calculated campaign to undermine it. Jay Bhattacharya, RFK & Vinay Prasad were all accomplices in destroying trust in vaccines & science in general. More people will die as a result. www.washingtonpost.com/opinions/202...
Opinion | Jay Bhattacharya: Why the NIH is pivoting away from mRNA vaccines
As a vaccine for broad public use, mRNA technology has failed to earn the public’s trust.
www.washingtonpost.com
August 12, 2025 at 8:42 PM
I can’t believe it- I’m nearly a year into my postdoc but loving every moment of it with these people 🥰
August 4, 2025 at 11:30 PM
I want it on the record that I went to Trader Joe’s and ONLY bought 1 (ONE) thing. Plz be proud of me.
July 23, 2025 at 11:24 PM
Your research hits differently when you realize findings from it can lead to therapies that can help your own mom.

Note: she’s okay- this is in the context of microglial activation.
July 7, 2025 at 1:00 PM
Reposted by Casey Mahoney-Crane, Ph.D.
Breaking news: The National Institutes of Health has ceased terminating grants on politically sensitive topics after a federal judge ruled last week that the cancellations were illegal.
scim.ag/4l9MO8Y
Following court order, NIH ceases new terminations of politically sensitive grants
After a judge told agency to restore hundreds of killed grants, NIH backs off plans to cancel more existing projects
scim.ag
June 25, 2025 at 5:36 PM
Reposted by Casey Mahoney-Crane, Ph.D.
You know what’s fantastic?

In the midst of everything that is happening the lab team keeps knocking it out of the park.

Seriously - I give them impossible tasks and they just…

Deliver.

Amazing stuff.
a man says " well i gotta say i 'm impressed " in front of a mirror
ALT: a man says " well i gotta say i 'm impressed " in front of a mirror
media.tenor.com
June 13, 2025 at 9:25 PM
Reposted by Casey Mahoney-Crane, Ph.D.
To everyone still reviewing papers right now: thank you. It's a lot to give up your time, for free, amidst everything. The scientific process remains as important as ever, and yet it's extra tough to serve in this capacity when our mental bandwidth is so limited.
June 11, 2025 at 2:00 PM
Reposted by Casey Mahoney-Crane, Ph.D.
GOOD NEWS!

The NIH guide notice prohibiting grantees from engaging in or promoting DEI activities or from engaging in "prohibited boycotts" (such as BDS) has been rescinded!!!!

grants.nih.gov/grants/guide...
a cartoon character says good news in front of a futurama sign
ALT: a cartoon character says good news in front of a futurama sign
media.tenor.com
June 9, 2025 at 2:49 PM
Reposted by Casey Mahoney-Crane, Ph.D.
I just signed.
I wanted to show support for these brave public servants and to allow others, including the scientific community, to join me. In partnership with @standupforscience.bsky.social‬, we have a way for you to do that... www.standupforscience.net/bethesda-dec...
Bethesda Declaration — STAND UP FOR SCIENCE
Support NIH Staff Now!
www.standupforscience.net
June 9, 2025 at 4:12 PM
Never in a million years did I think my “Girls just want to have funding for scientific research” sweatshirt, would turn into a political statement.

I’m just trying to study the brain, and that costs money😂😆
May 21, 2025 at 12:57 PM
Reposted by Casey Mahoney-Crane, Ph.D.
REMINDER.....REMINDER......REMINDER

3 DAYS LEFT TO COMMENT ON SCHEDULE F

1/n
gumball and anais from the amazing world of gumball are sitting at a table
ALT: gumball and anais from the amazing world of gumball are sitting at a table
media.tenor.com
May 20, 2025 at 8:33 PM
Reposted by Casey Mahoney-Crane, Ph.D.
Today, NIH Fellows United and our colleagues walked out of NIH Director Jayanta Bhattacharya’s Town Hall. Dr. Bhattacharya's tenure at NIH has been marked with damaging cuts to NIH personnel and biomedical research funding.
May 19, 2025 at 6:06 PM
This and not worrying about my cells because my AMAZING coworkers are taking care of them while I’m out of town. (Seriously, thank you amazing coworkers.)
May 16, 2025 at 3:53 PM
Reposted by Casey Mahoney-Crane, Ph.D.
In this time of uncertainty we are certain that we are committed to ending #Alzheimer and #Dementia so here are a few #Sciencerockstar sightings for you from the #NACC #ADRCSpringMeeting in #SFO
May 8, 2025 at 1:20 AM
Reposted by Casey Mahoney-Crane, Ph.D.
Our of office message:

I'm sorry I won't be responding to emails today. I'm out in the garden, healing my tired soul with dirt and sunshine
May 7, 2025 at 8:50 PM
I just found my new favorite gif- possibly ever to exist. And you’re welcome in advance.
May 3, 2025 at 12:43 PM
Reposted by Casey Mahoney-Crane, Ph.D.
I hope everyone knows that it's very easy for any social content platform, including Bluesky, to be a misery machine and that if you aren't intentional about it, they will absolutely decrease the positive impact you have on the world while making you less happy.
May 2, 2025 at 3:05 PM
Reposted by Casey Mahoney-Crane, Ph.D.
President Donald Trump today asked Congress to make massive and unprecedented cuts to the 2026 budgets of major federal science agencies. scim.ag/3Yszqnm
Trump’s proposed budget would mean ‘disastrous’ cuts to science
Key research budgets would shrink by one-third to one-half in 2026 spending plan
scim.ag
May 2, 2025 at 10:06 PM
As scientists, we sometimes push boundaries (ethically of course) to pursue quality research- that’s why earlier this week I loaded 515 ul into a tube with max capacity of 500 ul.

#Innovation
May 2, 2025 at 1:15 PM