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Otago Biochemistry @otagobiochemist.bsky.social · 10h

Latest publication with a contribution from Otago Biochemistry
Beyond single references: pangenome graphs and the future of genomic medicine
www.frontiersin.org/journals/gen...

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Otago Biochemistry @otagobiochemist.bsky.social · 10h

Latest publication from Otago Biochemistry
RNF114, a RING E3 ligase that reads and extends the hybrid ADP-ribose-ubiquitin signal
www.embopress.org/doi/full/10....

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Otago Biochemistry @otagobiochemist.bsky.social · 11h

Journal Club – Fri 10 Oct 12pm, RmBIG13.
Matthias Fellner: When Machines Become Our Moral Loophole. Köbis, N., et al. Delegation to artificial intelligence can increase dishonest behaviour. Nature (2025). doi.org/10.1038/s415...

Delegation to artificial intelligence can increase dishonest behaviour - Nature

People cheat more when they delegate tasks to artificial intelligence, and large language models are more likely than humans to comply with unethical instructions—a risk that can be minimized by introducing prohibitive, task-specific guardrails.

doi.org

Reposted by Otago Biochemistry

Ellinor Alseth @ellinoralseth.bsky.social · 23h

Obsessed with this Journal of Immaterial Science article 🔥

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Reposted by Otago Biochemistry

Lorne Proteins @lorneproteins.bsky.social · 1d

🎨 Design the Next Lorne Proteins T-Shirt!
Got an eye for design? We’re calling on creative scientists to design the official 2026 conference T-shirt!
📅 Entries close 10 November 2025
👉 Submit your design here:
#LorneProteins #TshirtCompetition #CreativeScience

T-Shirt Competition Entry Form

docs.google.com

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Otago Biochemistry @otagobiochemist.bsky.social · 1d

If you're around Dunedin in October, pop over to Waitati and appreciate a little beauty at the botanical art exhibition - features some beautiful works by Otago Biochemist Assoc Prof Sigurd Wilbanks.

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Reposted by Otago Biochemistry

Compound Interest | Chemistry infographics @compoundchem.com · 1d

With the 2025 Nobel Prize in Chemistry being announced tomorrow, here's a reminder of the research on protein structure prediction that won last year's prize: www.compoundchem.com/2024/10/10/2...

#ChemSky 🧪

The 2024 Nobel Prize in Chemistry was awarded to David Baker for computational protein design and to Demis Hassabis and John M. Jumper for protein structure prediction. Proteins are important biological molecules formed from 20 naturally occurring amino acids. Proteins form folded 3D structures which are key to their function and properties, but the exact way in which they fold is hard to predict. In 2020, Demis Hassabis, John Jumper and their co-workers unveiled an artificial intelligence model called AlphaFold2 to predict 3D folded structures of proteins. David Baker developed Rosetta, software that also attempts to predict protein structures, and used it to start with a protein structure and use the software to work out its amino acid sequence. Predicting and designing protein structures benefits the design of protein-based drugs, sensors, vaccines, catalysts, and more. It also aids our understanding of existing proteins and how they interact with other molecules.

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Reposted by Otago Biochemistry

Te Ara Paerangi Com - Research Advocacy Capability @te-ara-paerangi.community · 1d

We'd love to have a huge turn out for Nic's talk. Please help spread the word. There are downloadable pdf adverts in the link below. They can be emailed or printed. If you work in a public space (e.g. Library) you could help by printing and posting one of the flyers. Ngā mihi nui!

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Reposted by Otago Biochemistry

Timothy Bredy @twbredy.bsky.social · 9d

RNA and Proteins: Who Bosses Whom? | Science | AAAS www.science.org/content/blog...

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Otago Biochemistry @otagobiochemist.bsky.social · 3d

Department of Biochemistry Seminar
Wed 8 Oct 12pm, Rm BIG13
Professor Andrej Luptak
Departments of Pharmaceutical Sciences, Chemistry and Molecular Biochemistry, University of California Irvine
Illuminating RNA Worlds

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Otago Biochemistry @otagobiochemist.bsky.social · 7d

Latest publication from Otago Biochemistry.
Impacts of marine heatwave stress and harmful algal (Alexandrium spp.) exposure on subadult green-lipped mussels (Perna canaliculus)
www.sciencedirect.com/science/arti...

Impacts of marine heatwave stress and harmful algal (Alexandrium spp.) exposure on subadult green-lipped mussels (Perna canaliculus)

Marine heatwaves (MHWs) are increasing globally, including around Aotearoa New Zealand (NZ), where the Tasman Sea is a recognised hotspot. Harmful alg…

www.sciencedirect.com

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Reposted by Otago Biochemistry

eLife @elife.bsky.social · 7d

Cryogenic electron microscopy has been used to determine the detailed structure of an intermediate state called a “D-loop” that forms when strands of DNA are exchanged during homologous recombination.
buff.ly/pZZfIso

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Otago Biochemistry @otagobiochemist.bsky.social · 7d

Journal Club – Fri 3 Oct 12pm, Rm BIG13
Caleb Trimble: Getting ahead of the curve in the treatment of rheumatoid arthritis.
doi.org/10.1126/scit...

Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation

Individuals at risk for rheumatoid arthritis exhibit inflammation and immune dysregulation before and during transition to active disease.

doi.org

Otago Biochemistry @otagobiochemist.bsky.social · 7d

Mind blown!
(Thanks @notjustdna.bsky.social)

Kate Cavanaugh @katecavanaugh.bsky.social · 7d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

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Otago Biochemistry @otagobiochemist.bsky.social · 8d

Prof Kurt Krause has been awarded funding in the latest Smart Ideas investment round for his research into how the wonderful NZ glowworms make light. (That's right, they're carnivorous maggots, folks!)

www.otago.ac.nz/news/newsroo...

Biochemists bet on bioluminescent bugs for biomedical biotech

Otago Biochemistry’s Professor Kurt Krause and his research team are exploring the mechanism behind the glow of Aotearoa New Zealand’s native glowworm or titiwai (Arachnocampa luminosa), with the aim ...

www.otago.ac.nz

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Otago Biochemistry @otagobiochemist.bsky.social · 8d

There’s a vacancy for a protein biochemist in a new Dunedin-based biotech startup! www.seek.co.nz/job/87464044

Staff Scientists – Protein Expression & Assay Development Job in North Dunedin, Otago - SEEK

Wanted: Scientists with protein expertise to join our team at Platypus Bio developing transformative CRISPR-based tools for clinical use.

www.seek.co.nz

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Reposted by Otago Biochemistry

Nick Greeves @nickgreeves.bsky.social · Jun 1

Gemini offered to draw a diagram of the transition state of an SN2 reaction.

Like a fool I asked it to go ahead!

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Reposted by Otago Biochemistry

Andrew Gulick @amgulick-lab.bsky.social · 26d

When I've had a few spare minutes for the past few weeks, I've spent it browsing the literature and writing emails to authors of enzymology papers who are not part of the EMC mailing list.

www.enzymemechanismsconference.org

Too many people who otherwise should don't know about this gem.

Screen capture of text from EMC invitation email

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Reposted by Otago Biochemistry

Stephen Heard @stephenbheard.bsky.social · 8d

Writing a scientific paper Discussion is hard. But it needn't be as hard as it sometimes feels - there's help out there. Starting with three common mistakes you can avoid!

What your Discussion section isn’t

Today, the next instalment in a short series inspired by bad papers I’ve read (some of them, I have to admit, my own). I’ve let myself rant about what a Methods sections shouldn’t be, and what a Re…

scientistseessquirrel.wordpress.com

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Otago Biochemistry @otagobiochemist.bsky.social · 9d

Photosyntheticly phenomenal

Ben Engel @cellarchlab.com · 13d

Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on!

#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
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Otago Biochemistry @otagobiochemist.bsky.social · 9d

Pretty!!!!

(GIRISH)MALI LAB @dyneinassembly.bsky.social · 9d

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.

Open access link below:
www.nature.com/articles/s41...

Here's a cool animated summary

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Reposted by Otago Biochemistry

EMBL Events @events.embl.org · Jul 17

Ready to explore what's next in the life sciences? 🧬🔍 Then check out our new 2026 EMBL Annual Poster 👉 s.embl.org/2026-poster

Join us for another year of asking the big questions in the life sciences. See you in 2026?

#EMBL #lifesciences #molecularbiology #bioinformatics

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Reposted by Otago Biochemistry

Josh Hardy @joshuamhardy.bsky.social · 10d

I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign

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Otago Biochemistry @otagobiochemist.bsky.social · 13d

Listen to Sankalita Ray Das, postdoctoral fellow at Otago Biochemistry, talk about her research journey on the LabMates podcast!
Youtube: youtu.be/8Rt3o6P0xog
Apple: lnkd.in/gbKmrWtv
Spotify: lnkd.in/gyMJKgKS

Beyond the Bench: Episode 8: Dr Sankalita Ray Das, Postdoctoral Research Fellow

YouTube video by LabMates

youtu.be

Otago Biochemistry @otagobiochemist.bsky.social · 13d

Journal Club – TODAY, 12pm, Rm BIG13
Erin Delargy: Ancient host-associated microbes obtained from mammoth remains www.cell.com/cell/fulltex...
Julian Eaton-Rye: What is a smart canopy? www.nature.com/articles/s41...

Ancient host-associated microbes obtained from mammoth remains

A study of 483 mammoth remains spanning over a million years reveals ancient host-associated microbes preserved in bones and teeth, offering new insights into the long-term evolution of Pleistocene mi...

www.cell.com

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