Lightnews — Scholar-powered news

Eurico Morais-de-Sá

@polarityi3s.bsky.social

910 followers 340 following 25 posts

Drosophilist & Biochemist interested in cell asymmetries. Epithelial Polarity & Cell Division Lab https://www.i3s.up.pt/research-group.php?groupid=123

www.i3s.up.pt

Posts Media Videos Starter Packs

Pinned

Eurico Morais-de-Sá @polarityi3s.bsky.social · Nov 15

First official post! A new paper out about #cytokinesis in #epithelia

www.embopress.org/doi/full/10....

Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.

1 14 49

Reposted by Eurico Morais-de-Sá

Daniel J. Cohen (Princeton) @djcohen.bsky.social · 8d

So: can a cell hold hands with itself…and do we care? YES and YES! Read on to learn WHY, HOW, and what this has to do with…PARIS (and tree-hugging)? Swansong of Dr. Anamika; Hannah Kim on drums; and fantastic undergrads (Margaret/Lauren) ! 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/...

1 9 23

Reposted by Eurico Morais-de-Sá

Kate Cavanaugh @katecavanaugh.bsky.social · 7d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

11 68 220

Reposted by Eurico Morais-de-Sá

kuba sędziński @kuba-sedzinski.bsky.social · 16d

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

8 37 120

Reposted by Eurico Morais-de-Sá

epithelial mechanics fan club @epimechfc.bsky.social · 25d

How can we use cell shapes and geometry to study mechanics of tissues?

I'm @juliaeckert.bsky.social, and with this thread, I would like to show you the secrets of cells and tissues. Let’s connect biology with a little bit of physics. Don't be scared and get inspired 😀. #EpithelialMechanics

2 15 55

Reposted by Eurico Morais-de-Sá

Journal of Cell Biology @jcb.org · Sep 3

Our new collection offers cell biologists practical, expert-driven guidance and best practices in the design, execution, and analysis of experiments, and the subsequent communication of their results to their peers. 👉 rupress.org/jcb/collecti...

#Reproducibility

1 28 37

Reposted by Eurico Morais-de-Sá

@bilderlab @bilderlab.bsky.social · Jun 30

Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com‬. Thanks to the leaders in the field for welcoming me as an invertebrate researcher.
rdcu.be/etKdN

Advancing cancer research via comparative oncology

Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...

rdcu.be

15 20

Reposted by Eurico Morais-de-Sá

epithelial mechanics fan club @epimechfc.bsky.social · Jun 29

Epithelial morphogenesis is all about how epithelial tissues develop unique shapes and structures! I'm @nehaghosh.bsky.social and will share some research in this area.

1 11 32

Reposted by Eurico Morais-de-Sá

François Leulier @francoisleulier.bsky.social · Jun 28

A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation: Cell
1/2

www.cell.com/cell/abstrac...

A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation

This work introduces Flysta3D-v2, a 3D spatiotemporal multi-omics database that spans Drosophila development from embryogenesis to metamorphosis. Through the integration of multimodal data, we detail ...

www.cell.com

2 8 21

Reposted by Eurico Morais-de-Sá

Maik Bischoff @maikbischoff.bsky.social · Jun 18

FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!

It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀

www.science.org/doi/10.1126/...

#DevBio #CellBio #Microscopy

12 42 210

Reposted by Eurico Morais-de-Sá

Michael Rera @michaelrera.bsky.social · Jun 19

extremely happy to present the final version of our "smurf mice" paper www.biorxiv.org/content/10.1..., led by Céline Cansell when she was a postdoc in my group (now an independent @inrae-france.bsky.social researcher).
Disclaimer: no blue mice here alas BUT clearly a biphasic ageing process

Intestinal permeability significantly increased 30 days prior to death in AKR/J females

Fat mass decreases significantly in the last month of life

body temperature drops significantly in the last month of life

3 6 24

Reposted by Eurico Morais-de-Sá

RedPen/BlackPen @redpenblackpen.bsky.social · Feb 19

A reminder in these hard times. #sciencestrong

Cartoon showing a woman looking in to a microscope saying "Whoaah!!!" The caption states "The best part of Science is knowing, for a moment, something that nobody else in the world knows"

3 45 140

Reposted by Eurico Morais-de-Sá

Shane Herbert @shaneherbert.bsky.social · May 6

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis

During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

www.science.org

3 48 170

Reposted by Eurico Morais-de-Sá

EDRC2025 @edrc2025.bsky.social · Apr 29

#EDRC2025 👇🏻👇🏻👇🏻👇🏻

EDRC2025 @edrc2025.bsky.social · Apr 22

Remember to get your #EDRC2025 workshop proposal in before the 5th of May!

EDRC2025 @edrc2025.bsky.social · Apr 7

📣The #EDRC2025 will select proposals for six workshops, each with up to nine speakers (12 minutes presentations + 3 minutes Q/A). If you are interested in hosting a workshop, please send a one-page proposal to [email protected] by May 5, 2025 🧪🪰

1 4 1

Reposted by Eurico Morais-de-Sá

Rodrigo Fernandez-Gonzalez @rodrigofg.bsky.social · Apr 25

Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!

Program and application instructions for the 2025 Mechanobiology of tissue morphogenesis and disease workshop in Baeza, Spain, October 21-23. Apply at https://www.unia.es/estudios-y-acceso/oferta-academica/formacion-continua/workshop-mechanobiology-of-tissue-morphogenesis-and-disease

1 40 58

Reposted by Eurico Morais-de-Sá

Maik Bischoff @maikbischoff.bsky.social · Apr 25

#CellMigration 𝐢𝐧 𝐯𝐢𝐯𝐨!
Excited to share this video on #FluorescenceFriday 🌈
Today as a GIF to circumvent video compression 😅!

Migratory Nascent Myotubes on #Drosophila Testes. Marker: Lifeact-eGFP. Scope: 980 Airyscan (@zeiss-microscopy.bsky.social)

#cellbio #sciart #devbio #science #microscopy

2 18 93

Reposted by Eurico Morais-de-Sá

Mark Peifer (He, him) @peiferlabunc.bsky.social · Dec 18

Cell and developmental biologists: as you start looking at conferences in 2025, consider joining us at the 2025 Cell Contact & Adhesion GRC. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost
www.grc.org/cell-contact...

Poster for the meeting including speaker list and location

2 24 55

Reposted by Eurico Morais-de-Sá

epithelial mechanics fan club @epimechfc.bsky.social · Apr 20

1/14 “Epithelial” & “Mesenchymal” aren’t binary categories—they form a spectrum, or better yet, a multidimensional space. This becomes especially clear in collective cell migration, which often depends on a finely tuned degree of “mesenchymal-ness”.

#cellbio #devbio #cellmigration

3 40 120

Eurico Morais-de-Sá @polarityi3s.bsky.social · Apr 14

Muitos Parabéns Jorge! Isso tem que ser celebrado🍾

1 1

Reposted by Eurico Morais-de-Sá

Carlos Conde @carlos-conde.bsky.social · Apr 13

I'm happy to share our study “Proximity-based activation of AURORA A by MPS1 potentiates error correction” now published at @currentbiology.bsky.social

www.sciencedirect.com/science/arti...

It describes a new way kinetochores and centrosomes communicate to ensure accurate chromosome segregation.

Proximity-based activation of AURORA A by MPS1 potentiates error correction

Faithful cell division relies on mitotic chromosomes becoming bioriented with each pair of sister kinetochores bound to microtubules oriented toward o…

www.sciencedirect.com

1 11 26

Reposted by Eurico Morais-de-Sá

Andreas Prokop @poppi62.bsky.social · Apr 10

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

100 93

Reposted by Eurico Morais-de-Sá

MwahahahahahadScientist @mads100tist.bsky.social · Apr 10

Same for ZFIN! @zfinmod.bsky.social put them in your papers' acknowledgements and cite them (Bradford et al. 2022 academic.oup.com/genetics/art...)

17 26

Reposted by Eurico Morais-de-Sá

Laboratory of Genomic Stability @lgs-imb.bsky.social · Apr 7

We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology.
www.nature.com/articles/s41...

1 27 68

Reposted by Eurico Morais-de-Sá

Robert Arkowitz @robertarkowitz.bsky.social · Apr 5

Genetically encoded reporters of actin filament organization in living cells and tissues: Cell www.cell.com/cell/fulltex...

Genetically encoded reporters of actin filament organization in living cells and tissues

Tailoring genetic fusions of widely used actin localization reporters by constraining the mobility of the fluorescent proteins allows measurements of actin filament organization in living cells and ti...

www.cell.com

8 28

Reposted by Eurico Morais-de-Sá

Araújo Lab @araujolabub.bsky.social · Mar 26

Great team effort from our SGR group “REGnetREG” . Find out more by downloading this review 👇🏻👇🏻👇🏻

Genetics UB @geneticsub.bsky.social · Mar 26

🧬 New article from the SGR "REGnetREG" @geneticsub.bsky.social @biologiaub.bsky.social about "Cell Death in Regeneration and Cell Turnover: Lessons from Planarians and Drosophila".

📄 Enjoy 50 days of free access to the article at this link:

👇👇👇👇👇👇👇
www.sciencedirect.com/science/arti... 1/2

1 4

Reposted by Eurico Morais-de-Sá

Thomas Lecuit @thomaslecuit.bsky.social · Mar 20

⭐️ Please Fwd. Are you in Paris on 16th May? See👇 poster of symposium on « Information processing in biological systems » @collegedefrance.bsky.social Fantastic line of speakers 🤩.
It is free, w/o registration, and it will be exciting.m!
Follows from my series of lectures at CdF last fall.

2 46 69