Getting asked about how academics can continue to do science & inspire trainees even in the midst of a continued (escalated) assault on science, reason, truth, & human rights. I don’t have great answers.

I would love to hear from mentors about advice they’re giving to trainees/ colleagues.

🚨The Neurocyto lab is branching out in our latest preprint! We used tubulin microinjection to directly visualize microtubule turnover in developing hippocampal neurons, demonstrating the presence of in-lattice repair and a selective stabilization in the nascent axon. Check below, or read on 🧵 1/9

#HappyNewYear !
Let's start 2026 with a @cellcommlab.bsky.social paper

How many branches is OK during #CellMigration?
It depends on the #cell: for ex. immune cells are just fine.

In collab. w. #NirGov @hfspo.bsky.social

Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬

Macrophage fireworks 🎆 from Miller et al. of the @mmorrissey.bsky.social lab (doi.org/10.1083/jcb....) showing a #macrophage expressing Vav1-mCherry (magenta) interacting with IgG (yellow) on a supported lipid bilayer containing ICAM-1. More in JCB's December issue: rupress.org/jcb/issue/22...

Time-lapse movie of mitochondria (blue) transport within neurons (green) in the tail of a transgenic #zebrafish larva. Credit to @paquetlab.bsky.social. #ZebrafishZunday 🧪

New from Silvia Caballero, Stefania Castagnetti and friends - Embryonic development of the Mediterranean starfish Hacelia attenuata

www.biorxiv.org/content/10.6...

Malina Iwanski @mkiwanski.bsky.social, Lukas Kapitein and colleagues discover that stable microtubules reverse their polarity during neuronal development.
journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish

Long thought of as support cells, astrocytes are emerging as key players in health and disease

go.nature.com/4pJn859

Cellular structure self-organizes through an interplay between internal mechanisms and external cues. The single-celled suctorian P. collini builds a trap structure to capture large prey using microtubule feeding tentacles, creating feedback between cell morphology and prey availability.

Check it out at PNAS today. Thank you Alexandre for the collaboration!!

PK Mem probes offer long time-lapse imaging of cell membrane dynamics. Made possible by
Jing Ling, Yitong Liu, and all the collaborators!

Available @spirochrome.com

See study by @kirstin-rollins.bsky.social, @sareenfiaz.bsky.social, Ishwaree Datta and @mmorrissey.bsky.social: rupress.org/jcb/article/...

🔬 In JCB's November issue: image shows a #macrophage nibbling a #cancer cell. The bone marrow–derived mouse macrophage is expressing a Chimeric Antigen Receptor (green) that activates the Fc Receptor signaling pathway in response to Her2. From Rollins et al. rupress.org/jcb/issue/22...

We have TWO papers out in @jcb.org this month! 🎉

First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social

doi.org/10.1083/jcb....

Target cell adhesion limits macrophage #phagocytosis and promotes #trogocytosis, say @kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al.
@ucsantabarbara.bsky.social rupress.org/jcb/article/...

#Macrophages #Immunology