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Benoît Ladoux

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H-index: 64
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Reposted by: Benoît Ladoux

mpi-scienceoflight.bsky.social
With deep sadness, we share that Prof. Jochen Guck, Director at the Max Planck Institute for the Science of Light passed away on October 3. His visionary work bridged physics and medicine. We have lost a brilliant scientist and dear friend.

mpl.mpg.de/news/article...
@fau.de

📸 Stephan Spangenberg
Professor Jochen Guck, Director at the Max Planck Institute for the Science of Light (MPL), He headed the division “Cell Physics” at MPL and the Max-Planck-Zentrum für Physik und Medizin (MPZPM).
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Reposted by: Benoît Ladoux, Martin Tomko

drmlharris.bsky.social
Ahead of tomorrow’s #NobelPrize announcement, I went on a deep dive in search of the most obscure physics Nobel Prizes in history. That means it's time for a thread on...🧵

PHYSICS NOBEL PRIZES YOU’VE NEVER HEARD OF – PART 1

(1/n)
A photo of the Matterhorn rising above an Alpine landscape. The colours are a little washed out, but do not appear artificially tinted
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Reposted by: Benoît Ladoux

labliston.bsky.social
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
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Reposted by: Benoît Ladoux

djcohen.bsky.social
So: can a cell hold hands with itself…and do we care? YES and YES! Read on to learn WHY, HOW, and what this has to do with…PARIS (and tree-hugging)? Swansong of Dr. Anamika; Hannah Kim on drums; and fantastic undergrads (Margaret/Lauren) ! 1/n
advanced.onlinelibrary.wiley.com/doi/10.1002/...
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Reposted by: Benoît Ladoux

mattertolife.bsky.social
📣 Last chance to apply!
Applications for our URO program close tomorrow, October 1st.

Don't miss this opportunity:
mattertolife.maxplanckschools.org/uro-research...

👉 Funded 10-week research internship
👉 Learn from esteemed scientists
👉 No prior research experience required
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Reposted by: Benoît Ladoux

sarawickstrom.bsky.social
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology
McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.
www.nature.com
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Reposted by: Benoît Ladoux

gcharras.bsky.social
Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.

More here: elifesciences.org/reviewed-pre...
elifesciences.org
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Reposted by: Benoît Ladoux

davidbrueckner.bsky.social
How do cells navigate up gradients of adhesive proteins?
🤔

Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood

We show that passive friction directs cells & explains complex trajectories on gradients

👉 www.nature.com/articles/s41...
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Reposted by: Benoît Ladoux

epimechfc.bsky.social
Grata, A., & Levayer, R. (2025). Epithelial cell extrusion at a glance. Journal of Cell Science, 138(8), #EpithelialMechanicsReview doi.org/10.1242/jcs....
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Reposted by: Benoît Ladoux

lennarthilbert.bsky.social
What a great doctoral defense by Tim Klingberg @fau.de

Based in the group of our collaborator @vasilyzaburdaev.bsky.social Tim decisively contributed to at least 3 of our own lab’s foundational projects, which he showed today at “Max Planck Zentrum Physik und Medizin”

Some impressions
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by Benoît Ladoux

bladoux.bsky.social
Exciting science in Leipzig at the Physics of Cancer Meeting.
conference.uni-leipzig.de/poc/2025/
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Reposted by: Benoît Ladoux

mpipks.bsky.social
IG Nobel Prize in #Physics 2025 to @mpipks.bsky.social researchers for elucidating the phase behaviour of cacio e pepe sauce. The work highlights how physics can also be applied to solve daily-life problems!

nature.com/articles/d41586-025-03045-0
Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research
The annual awards are a celebration of weird but thought-provoking science.
nature.com
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by Benoît Ladoux

bladoux.bsky.social
We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.

mikeinmemoriam.sciencesconf.org
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Reposted by: Benoît Ladoux

parisseminar.bsky.social
Forces at Play: emerging themes in Mechanobiology - In memoriam of Pr. Michael Sheetz,
In Paris,  at the Institut Jacques Monod,  from January 19th to January 21st 2026.

The registration is now open, and the rates are quite low.

Dead line: end of November

mikeinmemoriam.sciencesconf.org
In memoriam of Prof. Michael P. Sheetz – Forces at Play: emerging themes in Mechanobiology - Sciencesconf.org
mikeinmemoriam.sciencesconf.org
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Reposted by: Benoît Ladoux, John De Vos

denisduboule.bsky.social
Out today. 🙏 again to everyone for this wonderful piece of work, in particular to Aurelie @aurhin.bsky.social Chase @chasebolt.bsky.social and Brent @homeobox.bsky.social. 🙏 also to the Harris lab @fish4walking.bsky.social and @neilshubin.bsky.social @biology-unige.bsky.social @college-de-france.fr
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by Benoît Ladoux

bladoux.bsky.social
www.biorxiv.org/content/10.1...
SCHEPHERD: A universal platform for high-throughput, high-resolution, and programmable control of cell behavior through bioelectric stimulation
Spanning frogs, fish, and humans, direct-current (DC) bioelectric cues play critical roles beyond neuro-muscular function, such as modulating morphogenesis, immune response, and healing through electr...
www.biorxiv.org
2

by Benoît Ladoux

bladoux.bsky.social
Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics.
Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri!
www.biorxiv.org/content/10.1...
Regulation of epithelial tissue homeostasis by active trans-epithelial transport
Epithelia are intricate tissues whose function is intimately linked to mechanics. While mechanobiology has primarily focused on factors such as cell-generated contractility and mechanical properties o...
www.biorxiv.org
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by Vincent Lemire — Reposted by: Benoît Ladoux, Dominique Bourg

vincent-lemire.bsky.social
🔥 "Gaza brûle !" annonce fièrement ce matin le ministre de la Défense Israël Katz, qui confirme le début de l'offensive terrestre sur Gaza-ville, avec l'engagement de 2 divisions (environ 30.000 hommes). Quelques données factuelles pour y voir clair, dans le flot des informations du moment:
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Reposted by: Benoît Ladoux

nature.com
Nature research paper: Energy deficiency selects crowded live epithelial cells for extrusion

go.nature.com/42tmu2l
Energy deficiency selects crowded live epithelial cells for extrusion - Nature
Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.
go.nature.com
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Reposted by: Benoît Ladoux

epimechfc.bsky.social
Hoffmann, L. A., Carenza, L. N., Eckert, J., & Giomi, L. (2022). Theory of defect-mediated morphogenesis. Science advances, 8(15), eabk2712. #EpithelialMechanics
buff.ly/wUYJE0s
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Reposted by: Benoît Ladoux, Nicole Dubilier

sarawickstrom.bsky.social
My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...
Computational image analyst (m/f/d)
The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a
jobs.mpi-muenster.mpg.de
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by Benoît Ladoux

bladoux.bsky.social
Very happy to share our new study from CAM team @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social (MPZPM) on the unanticipated “hidden fluidity” in jammed epithelia. Congrats to Yuan Shen and great collaboration with Walter Kob.
www.biorxiv.org/content/10.1...
The complex microscopic dynamics of cells in high-density epithelial tissues
Epithelial tissues line the surfaces of vital organs and are often densely packed in a disordered, mechanically arrested state, referred to as jammed or glassy state. While collective migration at low...
www.biorxiv.org
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by Benoît Ladoux

bladoux.bsky.social
🤔Altruism versus selfishness: impact on collective dynamics?
journals.aps.org/prl/abstract...
Hydrodynamics of Cooperation and Self-Interest in a Two-Population Occupation Model
Socioeconomic systems, where individualistic and altruistic agents coexist and interact, can be analytically characterized through state-of-the-art tools from active matter at the hydrodynamics scale.
journals.aps.org

by Benoît Ladoux

bladoux.bsky.social
Very nice work! Congrats.
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Reposted by: Benoît Ladoux

ijmonod.bsky.social
📢 PhD Thesis defense

📅 September 11th
📍 Institut Jacques Monod

Tomorrow, Andreas Schoenit @andreasschoenit.bsky.social will defend his PhD thesis "Mechanical forces in cell competition and epidermal stratification"

➡️ buff.ly/yhtJMsu
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Reposted by: Benoît Ladoux

thibautbrunet.bsky.social
New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵
Flagellar gliding in choanoflagellates
Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates, the closest relatives of animals. Under mild confinement, choanoflagellate move over surfaces without cell deformat...
www.cell.com
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by Benoît Ladoux

bladoux.bsky.social
Erlangen?
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Reposted by: Benoît Ladoux

manuelthery.bsky.social
Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Paris Cytoskeleton Day 2025 - Sciencesconf.org
pcd2025.sciencesconf.org
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by Vincent Lemire — Reposted by: Benoît Ladoux, Catherine Moury

vincent-lemire.bsky.social
⚠️ #Gaza: 83% de civils parmi les tués ; 75% de civils parmi les prisonniers.
• À partir des données de la Direction du Renseignement militaire israélien, @theguardian.com & le magasine israélien
@972mag.com révèlent ces chiffres terrifiants, sans aucune comparaison possible avec d'autres guerres:
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by Benoît Ladoux

bladoux.bsky.social
Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensions | Science Advances www.science.org/doi/10.1126/...
Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensions
This work demonstrates that changes in the nonlinear elasticity of collagen in hybrid networks tunes cell-matrix interactions.
www.science.org
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