Basil Greber
@bjgreber.bsky.social
Structural biologist. High-resolution imaging of macromolecular assemblies (and landscapes). MRC career development fellow/group leader at the Institute of Cancer Research, London. Views my own.
Reposted by Basil Greber
The two that first showed us how FACT engages nucleosomes now have their own lab and show us how the remodeler ATRX engages nucleosomes! Incredible resolution with a lot of biochemistry, congrats @codyz.bsky.social @yangliu9.bsky.social and team!
A collaborative work with Yang. @yangliu9.bsky.social
ATRX was considered as an orphan remodeler. We think it is truely unique.
www.biorxiv.org/content/10.6...
ATRX was considered as an orphan remodeler. We think it is truely unique.
www.biorxiv.org/content/10.6...
www.biorxiv.org
January 28, 2026 at 11:18 AM
The two that first showed us how FACT engages nucleosomes now have their own lab and show us how the remodeler ATRX engages nucleosomes! Incredible resolution with a lot of biochemistry, congrats @codyz.bsky.social @yangliu9.bsky.social and team!
Reposted by Basil Greber
"I didn’t realize, in the hours before his name was released to the public, that the man millions of people had seen lying facedown on the pavement from multiple angles of eyewitness video was my childhood best friend."
Read more from @kristenradtke.bsky.social: www.theverge.com/policy/86856...
Read more from @kristenradtke.bsky.social: www.theverge.com/policy/86856...
January 27, 2026 at 4:47 PM
"I didn’t realize, in the hours before his name was released to the public, that the man millions of people had seen lying facedown on the pavement from multiple angles of eyewitness video was my childhood best friend."
Read more from @kristenradtke.bsky.social: www.theverge.com/policy/86856...
Read more from @kristenradtke.bsky.social: www.theverge.com/policy/86856...
This horrific, and it contains the graphic original video. But if you can stomach it, you should watch it.
edition.cnn.com/2026/01/27/u...
edition.cnn.com/2026/01/27/u...
Exclusive: ‘Pink coat lady’ who recorded fatal encounter between federal officers and Alex Pretti speaks to Anderson Cooper | CNN
Anderson speaks with Stella Carlson, the witness who captured crucial video showing exactly what happened when Alex Pretti was shot and killed by DHS officers.
edition.cnn.com
January 28, 2026 at 9:29 AM
This horrific, and it contains the graphic original video. But if you can stomach it, you should watch it.
edition.cnn.com/2026/01/27/u...
edition.cnn.com/2026/01/27/u...
Reposted by Basil Greber
Our paper on the structural and functional basis of the human dimeric OS9–SEL1L–HRD1 ERAD complex, together with @qilabuva.bsky.social, is now out! Huge congratulations to Leo, Emir, and Elina!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 27, 2026 at 8:24 PM
Our paper on the structural and functional basis of the human dimeric OS9–SEL1L–HRD1 ERAD complex, together with @qilabuva.bsky.social, is now out! Huge congratulations to Leo, Emir, and Elina!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Basil Greber
"For The Homeland is not 'The State' or even 'The Country.' The Homeland is not defined by simple geography."
www.vanityfair.com/news/story/t...
www.vanityfair.com/news/story/t...
“The Homeland” Is War on America: The Blood-and-Soil Nationalism That Killed Renee Good and Alex Pretti
In the killings of Renee Good and Alex Pretti, Trump has clarified an inconvenient fact: The culture war is an actual war.
www.vanityfair.com
January 27, 2026 at 1:17 PM
"For The Homeland is not 'The State' or even 'The Country.' The Homeland is not defined by simple geography."
www.vanityfair.com/news/story/t...
www.vanityfair.com/news/story/t...
Reposted by Basil Greber
This "conflicting accounts" narrative of the BBC's is a much bigger problem than they seem to think.
The huge issue is not false balance - it's that they're NOT reporting the biggest story of today: the fact the US Government is lying about its own forces killing a US citizen.
The huge issue is not false balance - it's that they're NOT reporting the biggest story of today: the fact the US Government is lying about its own forces killing a US citizen.
January 25, 2026 at 3:52 PM
This "conflicting accounts" narrative of the BBC's is a much bigger problem than they seem to think.
The huge issue is not false balance - it's that they're NOT reporting the biggest story of today: the fact the US Government is lying about its own forces killing a US citizen.
The huge issue is not false balance - it's that they're NOT reporting the biggest story of today: the fact the US Government is lying about its own forces killing a US citizen.
Reposted by Basil Greber
A reminder to the news media: “conflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.
January 25, 2026 at 12:28 PM
A reminder to the news media: “conflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.
Reposted by Basil Greber
Reposted by Basil Greber
What happens when the taps run dry? England is about to find out | Aditya Chakrabortty
What happens when the taps run dry? England is about to find out | Aditya Chakrabortty
It’s not just Tunbridge Wells – a country famous around the world for its rain is in danger of self-imposed drought, says Guardian columnist Aditya Chakrabortty
www.theguardian.com
January 22, 2026 at 7:57 AM
What happens when the taps run dry? England is about to find out | Aditya Chakrabortty
Reposted by Basil Greber
A prominent Royal Society fellow helped out with this
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
January 21, 2026 at 8:24 AM
A prominent Royal Society fellow helped out with this
Reposted by Basil Greber
'“As regards the Nobel Peace Prize, I have on several occasions clearly explained to Trump what is well known, namely that it is an independent Nobel Committee, and not the Norwegian government, that awards the prize,” [Norwegian Prime Minister] Mr. Store said.'
Breaking News: President Trump told Norway’s prime minister that one reason he’s pushing to acquire Greenland is because he didn’t win the Nobel Peace Prize.
Denied Peace Prize, Trump Tells Norway He’ll Push for Greenland
In a text message, President Trump told Norway’s prime minister he no longer felt obliged to “think purely of Peace” and that the world would not be secure until America controlled the island.
nyti.ms
January 19, 2026 at 3:34 PM
'“As regards the Nobel Peace Prize, I have on several occasions clearly explained to Trump what is well known, namely that it is an independent Nobel Committee, and not the Norwegian government, that awards the prize,” [Norwegian Prime Minister] Mr. Store said.'
Reposted by Basil Greber
To remove any doubt, Norwegian PM Jonas Gahr Støre has confirmed to VG that this indeed is real.
It was received yesterday, as a response to a letter to Trump from Støre and Finnish President Stubb.
www.vg.no/nyheter/i/q6...
It was received yesterday, as a response to a letter to Trump from Støre and Finnish President Stubb.
www.vg.no/nyheter/i/q6...
January 19, 2026 at 9:36 AM
To remove any doubt, Norwegian PM Jonas Gahr Støre has confirmed to VG that this indeed is real.
It was received yesterday, as a response to a letter to Trump from Støre and Finnish President Stubb.
www.vg.no/nyheter/i/q6...
It was received yesterday, as a response to a letter to Trump from Støre and Finnish President Stubb.
www.vg.no/nyheter/i/q6...
Reposted by Basil Greber
We saw it with big tobacco, we saw it with the fossil fuels industry. When their own internal research showed the harm from their product, the defunded the research and attacked independent researchers coming to the very same conclusions.
#ScienceUnderSiege
#ScienceUnderSiege
Meta halted internal research that purportedly showed (young) people who stopped using Facebook became less depressed and anxious, according to an unredacted legal filing released on Friday. www.cnbc.com/2025/11/23/m...
Meta halted internal research suggesting social media harm, court filing alleges
Meta is alleged to have halted internal research suggesting social media harm, according to court documents.
www.cnbc.com
November 24, 2025 at 1:59 AM
We saw it with big tobacco, we saw it with the fossil fuels industry. When their own internal research showed the harm from their product, the defunded the research and attacked independent researchers coming to the very same conclusions.
#ScienceUnderSiege
#ScienceUnderSiege
Reposted by Basil Greber
Pew Research Institute (2023):
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
January 18, 2026 at 9:03 PM
Pew Research Institute (2023):
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
• Red State Texas has about 2.1 million undocumented immigrants
• Red State Florida has 1.6 M undocumented immigrants
• Blue State Minnesota has 130,000.
And yet only Minnesota is being occupied by masked thugs over "immigration."
It's *not* about immigration.
Reposted by Basil Greber
Photo by Pierre Lavie. Yes this is me. And I threw my Leica. It landed on the bass plate with hardly a scratch. Another Photographer grabbed it along with my phone and I was able to track him later. I was held face down tear gas deployed right in front of me and pepper sprayed directly into the eye.
January 17, 2026 at 2:57 PM
Photo by Pierre Lavie. Yes this is me. And I threw my Leica. It landed on the bass plate with hardly a scratch. Another Photographer grabbed it along with my phone and I was able to track him later. I was held face down tear gas deployed right in front of me and pepper sprayed directly into the eye.
Reposted by Basil Greber
Congrats JP, Mike and Jess and colleagues on the paper. Very interesting work.
A wonderful collaboration between Jess Tyler lab, @epicypher.bsky.social, @gcloner.bsky.social, James Kadonaga and our lab at PSU. In this article, we provide the significance of the nucleosome acidic patch.
doi.org/10.64898/202...
doi.org/10.64898/202...
doi.org
January 16, 2026 at 3:35 PM
Congrats JP, Mike and Jess and colleagues on the paper. Very interesting work.
Reposted by Basil Greber
Here's the data:
January 15, 2026 at 1:22 AM
Here's the data:
The final version of our article on XPF-ERCC1-SLX4 complexes has now been published (the link below still works). I am happy to report that the rendering of our DNA gels has now been corrected. 😉
Our latest paper on the molecular mechanisms of XPF-ERCC1 recruitment to SLX4-dependent DNA repair pathways has been published! Congratulations to first author Junjie Feng, and a heartfelt thank you to all our collaborators for their contributions to this study!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 15, 2026 at 11:48 AM
The final version of our article on XPF-ERCC1-SLX4 complexes has now been published (the link below still works). I am happy to report that the rendering of our DNA gels has now been corrected. 😉
Reposted by Basil Greber
Excited to share our new Nature study! 🧬
We (sidrituruci.bsky.social et al) discovered that CFAP20 helps clear stalled RNAPII, preventing harmful clashes with DNA replication machinery. This protects cells from R-loops and genome instability.
Full paper: www.nature.com/articles/s41...
We (sidrituruci.bsky.social et al) discovered that CFAP20 helps clear stalled RNAPII, preventing harmful clashes with DNA replication machinery. This protects cells from R-loops and genome instability.
Full paper: www.nature.com/articles/s41...
January 15, 2026 at 7:45 AM
Excited to share our new Nature study! 🧬
We (sidrituruci.bsky.social et al) discovered that CFAP20 helps clear stalled RNAPII, preventing harmful clashes with DNA replication machinery. This protects cells from R-loops and genome instability.
Full paper: www.nature.com/articles/s41...
We (sidrituruci.bsky.social et al) discovered that CFAP20 helps clear stalled RNAPII, preventing harmful clashes with DNA replication machinery. This protects cells from R-loops and genome instability.
Full paper: www.nature.com/articles/s41...
Reposted by Basil Greber
"“They specifically asked me if I knew where the Hmong families lived on my street & in the neighborhood.” Lugert-Thom responded, “I don’t know anything about that” & she said they then asked, “Well, what about the Asian families?”"
"“I was a bit shaken & a bit shocked of what I was asked to do.”"
"“I was a bit shaken & a bit shocked of what I was asked to do.”"
A St. Paul resident says federal officers knocked on her door and asked her to identify Hmong and Asian households in her North End neighborhood last week.
ICE in St. Paul: Man roughly detained at gas station, Border Patrol chief jeered in Midway Target
Videos and photos show a prevalence of federal agents in St. Paul recently.
trib.al
January 13, 2026 at 10:37 PM
"“They specifically asked me if I knew where the Hmong families lived on my street & in the neighborhood.” Lugert-Thom responded, “I don’t know anything about that” & she said they then asked, “Well, what about the Asian families?”"
"“I was a bit shaken & a bit shocked of what I was asked to do.”"
"“I was a bit shaken & a bit shocked of what I was asked to do.”"
Reposted by Basil Greber
There is nothing complex or subtle or hard to understand about what is happening here.
January 14, 2026 at 1:26 PM
There is nothing complex or subtle or hard to understand about what is happening here.
Reposted by Basil Greber
Disguising yourself as a civilian in order to carry out a lethal attack is called perfidy and it’s one of the most serious of war crimes. The usual punishment is execution.
U.S. Attacked Boat With Aircraft That Looked Like a Civilian Plane
www.nytimes.com
January 13, 2026 at 12:31 AM
Disguising yourself as a civilian in order to carry out a lethal attack is called perfidy and it’s one of the most serious of war crimes. The usual punishment is execution.
Reposted by Basil Greber
This is the insanity of the current Labour approach. You are kneecapping the economy by slashing immigration to appease voters who hover between Tory and Reform, and yet they don’t even believe your numbers anyway…plus you’ve just alienated your actual supporters
Two-thirds of UK voters wrongly think immigration is rising, poll finds.
Net migration to the UK fell by more than two-thirds to a post-pandemic low in the year ending June 2025, but 67% of the people polled thought it had increased
www.theguardian.com/uk-news/2026...
Net migration to the UK fell by more than two-thirds to a post-pandemic low in the year ending June 2025, but 67% of the people polled thought it had increased
www.theguardian.com/uk-news/2026...
Two-thirds of UK voters wrongly think immigration is rising, poll finds
Exclusive: Voters say they have little confidence that government can control borders despite sharp falls in net migration
www.theguardian.com
January 11, 2026 at 7:40 AM
This is the insanity of the current Labour approach. You are kneecapping the economy by slashing immigration to appease voters who hover between Tory and Reform, and yet they don’t even believe your numbers anyway…plus you’ve just alienated your actual supporters
Reposted by Basil Greber
The Norwegian Nobel Prize committee has been forced to make a statement, declaring that the prize cannot be transferred.
It's hard even to comprehend how stupid this has become
It's hard even to comprehend how stupid this has become
January 10, 2026 at 9:15 AM
The Norwegian Nobel Prize committee has been forced to make a statement, declaring that the prize cannot be transferred.
It's hard even to comprehend how stupid this has become
It's hard even to comprehend how stupid this has become