Matt Parkes
@mattyjparkes.bsky.social
Statistician. Interests: clinical trials methods, psychology, MSK medicine, rheumatology, oncology, chronic pain, adaptive trials, outcomes, digital health/wearables, Open Research, Stata, R, and code ligatures.
https://orcid.org/0000-0002-1574-9933
https://orcid.org/0000-0002-1574-9933
Reposted by Matt Parkes
1. Transparency is necessary for credibility
2. Transparency is hard to change
3. Require transparency*
4. Transparency is not magic
5. Journals are part of problem
6. Expect more from journals
7. Peer review is not magic
8. A crisis can look a lot like „normal“ science
9. Meta-analysis is not magic
2. Transparency is hard to change
3. Require transparency*
4. Transparency is not magic
5. Journals are part of problem
6. Expect more from journals
7. Peer review is not magic
8. A crisis can look a lot like „normal“ science
9. Meta-analysis is not magic
In case you have missed Simine Vazire's excellent webinar yesterday, here is the link to watch it online: youtu.be/_vb1CNwC3CM Thanks again @simine.com for staying up so late and thanks to the audience for the great questions!
PCI Webinar series #13 - Simine Vazire - Recognizing and responding to a replication crisis
youtu.be
December 3, 2025 at 9:40 AM
1. Transparency is necessary for credibility
2. Transparency is hard to change
3. Require transparency*
4. Transparency is not magic
5. Journals are part of problem
6. Expect more from journals
7. Peer review is not magic
8. A crisis can look a lot like „normal“ science
9. Meta-analysis is not magic
2. Transparency is hard to change
3. Require transparency*
4. Transparency is not magic
5. Journals are part of problem
6. Expect more from journals
7. Peer review is not magic
8. A crisis can look a lot like „normal“ science
9. Meta-analysis is not magic
Reposted by Matt Parkes
🚨New guidance for CTUs
Making optimal use of clinical trial data is an ethical obligation & often a funder requirement.
Our guidance, written by experienced trial staff, can help you prepare for data sharing & re-use requests.
🔗 ukcrc-ctu.org.uk/quality-assu...
#ClinicalTrials #UKCTUNetwork
Making optimal use of clinical trial data is an ethical obligation & often a funder requirement.
Our guidance, written by experienced trial staff, can help you prepare for data sharing & re-use requests.
🔗 ukcrc-ctu.org.uk/quality-assu...
#ClinicalTrials #UKCTUNetwork
November 24, 2025 at 10:25 AM
🚨New guidance for CTUs
Making optimal use of clinical trial data is an ethical obligation & often a funder requirement.
Our guidance, written by experienced trial staff, can help you prepare for data sharing & re-use requests.
🔗 ukcrc-ctu.org.uk/quality-assu...
#ClinicalTrials #UKCTUNetwork
Making optimal use of clinical trial data is an ethical obligation & often a funder requirement.
Our guidance, written by experienced trial staff, can help you prepare for data sharing & re-use requests.
🔗 ukcrc-ctu.org.uk/quality-assu...
#ClinicalTrials #UKCTUNetwork
Reposted by Matt Parkes
🎉 Announcing surveydown v1.0.0!
surveydown is an #opensource #rstats package for building surveys with #Quarto & #Shiny. This release improves the survey design experience, including:
- Simplified YAML settings
- Auto page navigation
- Previous buttons!
More at surveydown.org/blog/2025-11...
surveydown is an #opensource #rstats package for building surveys with #Quarto & #Shiny. This release improves the survey design experience, including:
- Simplified YAML settings
- Auto page navigation
- Previous buttons!
More at surveydown.org/blog/2025-11...
Announcing surveydown v1.0.0! – surveydown.org
We are thrilled to announce the v1.0.0 release of surveydown, a stable release with improvements to YAML settings, page navigation, question creation, and a smoother overall developer experience.
surveydown.org
November 25, 2025 at 9:53 PM
🎉 Announcing surveydown v1.0.0!
surveydown is an #opensource #rstats package for building surveys with #Quarto & #Shiny. This release improves the survey design experience, including:
- Simplified YAML settings
- Auto page navigation
- Previous buttons!
More at surveydown.org/blog/2025-11...
surveydown is an #opensource #rstats package for building surveys with #Quarto & #Shiny. This release improves the survey design experience, including:
- Simplified YAML settings
- Auto page navigation
- Previous buttons!
More at surveydown.org/blog/2025-11...
Very niche ask: if anyone on #statsky has used {rpact} to design a trial using a conditional power approach, please can I ask you a question?
It seems to be doing the opposite of what I'd expected it to do, but that might be because I don't understand it properly!
kthxbye
It seems to be doing the opposite of what I'd expected it to do, but that might be because I don't understand it properly!
kthxbye
November 25, 2025 at 2:30 PM
Very niche ask: if anyone on #statsky has used {rpact} to design a trial using a conditional power approach, please can I ask you a question?
It seems to be doing the opposite of what I'd expected it to do, but that might be because I don't understand it properly!
kthxbye
It seems to be doing the opposite of what I'd expected it to do, but that might be because I don't understand it properly!
kthxbye
Reposted by Matt Parkes
{ripper} dissects your #Quarto documents, extracting code blocks by language and leaving executable scripts behind.
Supports #rstats, #python, #julia, and 13 other victims.
For those who never stopped celebrating Halloween.
📚 quarto.thecoatlessprofessor.com/ripper/
💻 github.com/coatless-qua...
Supports #rstats, #python, #julia, and 13 other victims.
For those who never stopped celebrating Halloween.
📚 quarto.thecoatlessprofessor.com/ripper/
💻 github.com/coatless-qua...
November 22, 2025 at 10:57 PM
{ripper} dissects your #Quarto documents, extracting code blocks by language and leaving executable scripts behind.
Supports #rstats, #python, #julia, and 13 other victims.
For those who never stopped celebrating Halloween.
📚 quarto.thecoatlessprofessor.com/ripper/
💻 github.com/coatless-qua...
Supports #rstats, #python, #julia, and 13 other victims.
For those who never stopped celebrating Halloween.
📚 quarto.thecoatlessprofessor.com/ripper/
💻 github.com/coatless-qua...
Reposted by Matt Parkes
#rstats Please welcome Jarl, a new R linter.
Jarl is a CLI tool with extensions in VS Code, Positron, and Zed. It can check thousands of lines of R code in milliseconds.
Jarl provides several output formats, a Github Actions workflow, and more.
Blog post: www.etiennebacher.com/posts/2025-1...
Jarl is a CLI tool with extensions in VS Code, Positron, and Zed. It can check thousands of lines of R code in milliseconds.
Jarl provides several output formats, a Github Actions workflow, and more.
Blog post: www.etiennebacher.com/posts/2025-1...
November 20, 2025 at 4:50 PM
#rstats Please welcome Jarl, a new R linter.
Jarl is a CLI tool with extensions in VS Code, Positron, and Zed. It can check thousands of lines of R code in milliseconds.
Jarl provides several output formats, a Github Actions workflow, and more.
Blog post: www.etiennebacher.com/posts/2025-1...
Jarl is a CLI tool with extensions in VS Code, Positron, and Zed. It can check thousands of lines of R code in milliseconds.
Jarl provides several output formats, a Github Actions workflow, and more.
Blog post: www.etiennebacher.com/posts/2025-1...
Reposted by Matt Parkes
One thing about PCA/embeddings/political-leaning that should get more attention is the role of zero or “the origin”. It’s often special in a way that depends upon how you do the embedding.
This post is a good example of that.
Once you accept that the origin is special, then….
This post is a good example of that.
Once you accept that the origin is special, then….
Good morning. I've got a banger new post out today that develops a new method for placing voters on the left-right ideological spectrum, and adds a new, "non-ideological"/affordability axis to usual way we chart & think about US voters (esp swing voters). www.gelliottmorris.com/p/not-just-l...
Not just left vs right: Most voters think about affordability and material wellbeing, not in ideological terms
Most voters want a party that emphasizes cost of living issues and makes the world a better place. Few Americans think in solidly ideologically terms. "Moderates" are mostly non-ideological.
www.gelliottmorris.com
November 20, 2025 at 6:28 PM
One thing about PCA/embeddings/political-leaning that should get more attention is the role of zero or “the origin”. It’s often special in a way that depends upon how you do the embedding.
This post is a good example of that.
Once you accept that the origin is special, then….
This post is a good example of that.
Once you accept that the origin is special, then….
Reposted by Matt Parkes
One of my 2026 goals is to be more present on BlueSky! Another is to recruit a great candidate to this 4-yr PhD studentship with us at the Aberdeen Centre for Evaluation -applying behavioural science to the design and delivery of clinical trials. Please share. www.findaphd.com/phds/project...
Improving health by improving trials – applying behavioural science to improve the design and delivery of clinical trials. at University of Aberdeen on FindAPhD.com
PhD Project - Improving health by improving trials – applying behavioural science to improve the design and delivery of clinical trials. at University of Aberdeen , listed on FindAPhD.com
www.findaphd.com
November 20, 2025 at 6:38 PM
One of my 2026 goals is to be more present on BlueSky! Another is to recruit a great candidate to this 4-yr PhD studentship with us at the Aberdeen Centre for Evaluation -applying behavioural science to the design and delivery of clinical trials. Please share. www.findaphd.com/phds/project...
MNAR
Labor Department confirms cancellation of October jobs report
Labor Department confirms cancellation of October jobs report
The move was largely anticipated as federal workers were unable to conduct a key household survey due to the government shutdown.
dlvr.it
November 20, 2025 at 1:28 PM
MNAR
Incredibly helpful! No longer do we need to have awkward mid-lecture discussions about why this is so, can just point to this (great) post which does a much better job of explaining!
This is great.
Confidence interval discussion time! The perfect opportunity to repost this blog post answering the question you haven’t dared to ask: www.the100.ci/2024/12/05/w...
November 19, 2025 at 7:38 AM
Incredibly helpful! No longer do we need to have awkward mid-lecture discussions about why this is so, can just point to this (great) post which does a much better job of explaining!
Reposted by Matt Parkes
This is great.
Confidence interval discussion time! The perfect opportunity to repost this blog post answering the question you haven’t dared to ask: www.the100.ci/2024/12/05/w...
November 19, 2025 at 7:19 AM
This is great.
Reposted by Matt Parkes
Computational notebooks - the first in a set of posts on this topic. russpoldrack.substack.com/p/computatio...
Computational notebooks
Better Code, Better Science: Chapter 6, Part 4
russpoldrack.substack.com
November 18, 2025 at 4:29 PM
Computational notebooks - the first in a set of posts on this topic. russpoldrack.substack.com/p/computatio...
Reposted by Matt Parkes
Next: Jack Wilkinson @jdwilko.bsky.social with 'Problematic clinical trials and the threat to evidence synthesis'
Systematic reviews are considered the cornerstone of medicine. But some of the eligible trials that could be included might be problematic. They could get included.
#IRICSydney
Systematic reviews are considered the cornerstone of medicine. But some of the eligible trials that could be included might be problematic. They could get included.
#IRICSydney
November 17, 2025 at 10:30 PM
Next: Jack Wilkinson @jdwilko.bsky.social with 'Problematic clinical trials and the threat to evidence synthesis'
Systematic reviews are considered the cornerstone of medicine. But some of the eligible trials that could be included might be problematic. They could get included.
#IRICSydney
Systematic reviews are considered the cornerstone of medicine. But some of the eligible trials that could be included might be problematic. They could get included.
#IRICSydney
Reposted by Matt Parkes
Key concepts: FAIRification of biomedical research data - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
FAIRification of biomedical research data
The Findable, Accessible, Interoperable, and Reusable guiding principles promote Findability,
Accessibility, Interoperability, and Reuse of data to enhance data management and
stewardship. In biomedic...
www.jclinepi.com
November 17, 2025 at 7:12 PM
Key concepts: FAIRification of biomedical research data - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
Reposted by Matt Parkes
In between things I've been checking in on the emails that mention "university" and uhh did we all know about this connection?
![Screenshot from the Epstein Document Search which reads: House_Oversight_029401
From: Donald Rubin
Sent: 1/22/2017 7:31:32 PM
To: jeffrey E. [jeeyacation@gmail.com]
Subject: Republican health care experts dismiss Donald Trump's ideas
Importance: High
https://www.statnews.com/20 1 6/03/04/trump -repub cans-health-care/? s camp aign=trendmd
Jeffrey,
This cannot be true, can it? This guy must be as dumb about this stuff as a tampon laced with arsenic!!
HELP!
Great meeting yesterday — really enjoyed it.
And happy birthday again, Don
Donald B. Rubin
John L. Loeb Professor of Statistics
Department of Statistics, Harvard University
1 Oxford Street
Cambridge MA 02138
HOUSE OVERSIGHT 029401](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ozma3timm5c32fa7bimb4zaj/bafkreiezajc6f2rgwxrdx2242izbelpumkgdruc52pzu236rhovlcyfmde@jpeg)
November 13, 2025 at 6:30 PM
In between things I've been checking in on the emails that mention "university" and uhh did we all know about this connection?
Reposted by Matt Parkes
University of Manchester researchers and PGRs have access to a wide range of tools from #GitHub but it can be confusing to work out what you need and how to get access.
Have a look at this handy guide put together by out Head of Research Software Engineering, Adrian Harwood.
Have a look at this handy guide put together by out Head of Research Software Engineering, Adrian Harwood.
Getting Started with Git, GitHub & GitHub Copilot at the University of Manchester?
This guide introduces key tools in the software development lifecycle - Git, GitHub, and GitHub Copilot – and explains how University of Manchester staff and students can access them for free through…
buff.ly
November 12, 2025 at 5:09 PM
University of Manchester researchers and PGRs have access to a wide range of tools from #GitHub but it can be confusing to work out what you need and how to get access.
Have a look at this handy guide put together by out Head of Research Software Engineering, Adrian Harwood.
Have a look at this handy guide put together by out Head of Research Software Engineering, Adrian Harwood.
Reposted by Matt Parkes
NEW PAPER: "Reporting guidelines for studies involving generative artificial intelligence applications: what do I use, and when?"
--> www.nature.com/articles/s41...
#HealthTech #ClinicalAI #MachineLearning #MedAI #AIinMedicine #TransparentAI #HealthInnovation #GenAI
--> www.nature.com/articles/s41...
#HealthTech #ClinicalAI #MachineLearning #MedAI #AIinMedicine #TransparentAI #HealthInnovation #GenAI
November 7, 2025 at 12:44 PM
NEW PAPER: "Reporting guidelines for studies involving generative artificial intelligence applications: what do I use, and when?"
--> www.nature.com/articles/s41...
#HealthTech #ClinicalAI #MachineLearning #MedAI #AIinMedicine #TransparentAI #HealthInnovation #GenAI
--> www.nature.com/articles/s41...
#HealthTech #ClinicalAI #MachineLearning #MedAI #AIinMedicine #TransparentAI #HealthInnovation #GenAI
Reposted by Matt Parkes
On a cold, grey Friday afternoon, what better way to cheer ourselves up than by listening to a few episodes of the Trials Methodology Podcast?
Great topics, excellent interviews - and the enthusiasm is infectious!
🎧 Listen here: linktr.ee/trialsmethod...
#UKCTUNetwork #TMRP #TrialMethodology
Great topics, excellent interviews - and the enthusiasm is infectious!
🎧 Listen here: linktr.ee/trialsmethod...
#UKCTUNetwork #TMRP #TrialMethodology
November 7, 2025 at 12:13 PM
On a cold, grey Friday afternoon, what better way to cheer ourselves up than by listening to a few episodes of the Trials Methodology Podcast?
Great topics, excellent interviews - and the enthusiasm is infectious!
🎧 Listen here: linktr.ee/trialsmethod...
#UKCTUNetwork #TMRP #TrialMethodology
Great topics, excellent interviews - and the enthusiasm is infectious!
🎧 Listen here: linktr.ee/trialsmethod...
#UKCTUNetwork #TMRP #TrialMethodology
Reposted by Matt Parkes
Position statement on artificial intelligence (#AI) use in evidence synthesis across Cochrane, the Campbell Collaboration, JBI and the Collaboration for Environmental Evidence 2025 link.springer.com/article/10.1...
Position statement on artificial intelligence (AI) use in evidence synthesis across Cochrane, the Campbell Collaboration, JBI and the Collaboration for Environmental Evidence 2025 - Environmental Evid...
1. Evidence synthesists are ultimately responsible for their evidence synthesis, including the decision to use artificial intelligence (AI) and automation, and to ensure adherence to legal and ethical...
link.springer.com
November 4, 2025 at 8:34 PM
Position statement on artificial intelligence (#AI) use in evidence synthesis across Cochrane, the Campbell Collaboration, JBI and the Collaboration for Environmental Evidence 2025 link.springer.com/article/10.1...
Reposted by Matt Parkes
The package formerly known as papercheck has changed its name to metacheck! We're checking more than just papers, with functions to assess OSF projects, github repos, and AsPredicted pre-registrations, with more being developed all the time.
scienceverse.github.io/metacheck/
scienceverse.github.io/metacheck/
Check Research Outputs for Best Practices
A modular, extendable system for automatically checking research outputs for best practices using text search, R code, and/or (optional) LLM queries.
scienceverse.github.io
November 3, 2025 at 4:20 PM
The package formerly known as papercheck has changed its name to metacheck! We're checking more than just papers, with functions to assess OSF projects, github repos, and AsPredicted pre-registrations, with more being developed all the time.
scienceverse.github.io/metacheck/
scienceverse.github.io/metacheck/
Reposted by Matt Parkes
interesting paper on difference between synthetic contol method and historical counterfactual method www.cambridge.org/core/journal...
Contrasting and combining the historical counterfactual method and the synthetic control method | European Political Science Review | Cambridge Core
Contrasting and combining the historical counterfactual method and the synthetic control method
www.cambridge.org
November 3, 2025 at 10:00 AM
interesting paper on difference between synthetic contol method and historical counterfactual method www.cambridge.org/core/journal...
Reposted by Matt Parkes
We're excited to share our latest work on estimands in clinical trials!
📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands.
🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...
📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands.
🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
October 27, 2025 at 2:42 PM
We're excited to share our latest work on estimands in clinical trials!
📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands.
🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...
📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands.
🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...
Reposted by Matt Parkes
⏰ There's just one week to go until our free getting started with secondary analysis workshop!
Participants will learn about the key issues to consider when using secondary data analysis as a method.
📅 3 November 2025
⏰ 10:00-11:30
📍 Online
🧷 ukdataservice.ac.uk/events/getti...
Participants will learn about the key issues to consider when using secondary data analysis as a method.
📅 3 November 2025
⏰ 10:00-11:30
📍 Online
🧷 ukdataservice.ac.uk/events/getti...
Getting started with secondary analysis — UK Data Service
A comprehensive resource funded by the ESRC to support researchers, teachers and policymakers who depend on high-quality social and economic data.
ukdataservice.ac.uk
October 27, 2025 at 12:44 PM
⏰ There's just one week to go until our free getting started with secondary analysis workshop!
Participants will learn about the key issues to consider when using secondary data analysis as a method.
📅 3 November 2025
⏰ 10:00-11:30
📍 Online
🧷 ukdataservice.ac.uk/events/getti...
Participants will learn about the key issues to consider when using secondary data analysis as a method.
📅 3 November 2025
⏰ 10:00-11:30
📍 Online
🧷 ukdataservice.ac.uk/events/getti...
Reposted by Matt Parkes
📝 New Research Methods & Reporting article: Covariate adjustment in cluster randomised trials 📝
A practical guide for when and how to adjust for covariates. Read more ⬇️
www.bmj.com/content/391/...
A practical guide for when and how to adjust for covariates. Read more ⬇️
www.bmj.com/content/391/...
October 27, 2025 at 9:25 AM
📝 New Research Methods & Reporting article: Covariate adjustment in cluster randomised trials 📝
A practical guide for when and how to adjust for covariates. Read more ⬇️
www.bmj.com/content/391/...
A practical guide for when and how to adjust for covariates. Read more ⬇️
www.bmj.com/content/391/...