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Reposted by Natalie Turner

Ian Weissman, DO @drianweissman.bsky.social · 6d

Obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup of amyloid-β plaques in the brain.
www.sciencedaily.com/releases/202...

Fat may secretly fuel Alzheimer’s, new research finds

New research from Houston Methodist reveals how obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can ca...

www.sciencedaily.com

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Reposted by Natalie Turner

The Robert Mehrabian College of Engineering @ucsbengineering.bsky.social · Sep 9

Bioengineering assistant professor Marley Dewey has received a National Institutes of Health (NIH) research award to support her work on recently discovered extracellular vesicles that play an important role in tissue repair.👏

Click here to read more: engineering.ucsb.edu/news/marley-...

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Reposted by Natalie Turner

Science Magazine @science.org · Sep 9

The new issue of #ScienceSignaling is out!

A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6

The RNAscope image shows expression of the gene encoding the dopamine transporter in the brain of a fly that had butyrate supplemented in its diet.

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Natalie Turner @natalieturnerau.bsky.social · Sep 1

This is work that follows another study from our projects in Prof Mitchell’s group on EV #proteomics, published in JPR, 2023:

pubs.acs.org/doi/10.1021/...

If you’re interested in biomarker research, bioinformatics and applications to agricultural models, these are for you.

#extracellularvesicles

SWATH-MS Analysis of Blood Plasma and Circulating Small Extracellular Vesicles Enables Detection of Putative Protein Biomarkers of Fertility in Young and Aged Dairy Cows

The development of biomarkers of fertility could provide benefits for the genetic improvement of dairy cows. Circulating small extracellular vesicles (sEVs) show promise as diagnostic or prognostic ma...

pubs.acs.org

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Natalie Turner @natalieturnerau.bsky.social · Sep 1

EV-microRNAs may serve as early predictors of subfertility in dairy cows.

Congrats Pevindu for this final publication from his PhD and our time with Prof Murray Mitchell at QUT in Brisbane, Australia. 🇦🇺

#extracellularvesicles #biomarkers

isevjournals.onlinelibrary.wiley.com/doi/10.1002/...

MicroRNA (miRNA) in Plasma Small Extracellular Vesicles (sEV) as Potential Early Indicators of Dairy Cow Subfertility

Pregnancy and live birth rates are commonly used metrics to define fertility in humans and animals. The impact of aberrant microRNA (miRNA) expression on fertility-related genes represents a signific....

isevjournals.onlinelibrary.wiley.com

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Reposted by Natalie Turner

Cedars-Sinai Cancer @cedarssinaicancer.bsky.social · Jul 25

Dr. Dolores Di Vizio received the International Society for Extracellular Vesicles (ISEV) Special Achievement Award for her work showing large extracellular vesicles are functional mediators of #cancer progression. @isev.org
bioquicknews.com/isev-2025-sp...

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Reposted by Natalie Turner

Sierra Palumbos @palumbos.bsky.social · Jul 7

Very excited to share my postdoc work- out now at PNAS!

Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways

Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org

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Reposted by Natalie Turner

Nikolai Slavov @slavov-n.bsky.social · Jun 25

This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise:

357 validated antibodies out of 1,124 tested.

.

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Reposted by Natalie Turner

Eric Topol @erictopol.bsky.social · Jul 5

New organ clock data support the anti-aging benefits of estrogen for postmenopausal women. Reviewed here in context with previous and other recent reports.
erictopol.substack.com/p/new-anti-a...

Organ clocks for post-menopausal women taking estrogen or not taking estrogen

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Reposted by Natalie Turner

Andrea Sinz 🧪 @sinzandrea.bsky.social · Jun 25

‼️ Job alert 🚨: I have an open 3-year postdoc position in my lab to develop novel crosslinking mass spectrometry workflows. 🧪🧪 So if you want to do cool stuff in protein MS, please apply ! ⬇️ Please RT
www.verwaltung.uni-halle.de/dezern3/Auss...

#Academicsky
#Chemsky
#teammassspec

www.verwaltung.uni-halle.de

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Reposted by Natalie Turner

Ben Koch 🐛 @benkoch96.bsky.social · Jun 22

Excited to share part two of our plant extracellular vesicles story on BioRxiv! Using proximity labeling the awesome power of genetics to figure out how these lil’ guys are secreted.
Part one: doi.org/10.1002/jev2...
Part two:
www.biorxiv.org/content/10.1...

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Reposted by Natalie Turner

Kashmir Hill @kashhill.bsky.social · Jun 13

People are having very strange conversations with ChatGPT, in which they discover secret cabals or conspiracies or that we are all in fact living in The Matrix.

It sends these people into delusional spirals.

Then ChatGPT tells them to email me about it.

www.nytimes.com/2025/06/13/t...

They Asked an A.I. Chatbot Questions. The Answers Sent Them Spiraling.

www.nytimes.com

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Natalie Turner @natalieturnerau.bsky.social · Jun 13

You had me at ‘pew pew’ 😆
Of course a mass spec

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Natalie Turner @natalieturnerau.bsky.social · Jun 6

There is a pre=print on the way - Look out for more of this work from the lab of Prof Jeff Kelly and the Yates lab at Scripps in the coming months!

#extracellularvesicles #alzheimersdisease #organoids #proteomics

Natalie Turner @natalieturnerau.bsky.social · Jun 6

Excited for the discoveries these advances will lead to, and looking forward to #ASMS2026 in San Diego!

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Natalie Turner @natalieturnerau.bsky.social · Jun 6

—pushing the boundaries of mass spectrometry sensitivity and throughput for bottom-up and top-down proteomics, #PTM and #proteoform analysis, and enabling 4D- #proteomics.

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Natalie Turner @natalieturnerau.bsky.social · Jun 6

👏 It's been such a fantastic week filled with great networking opportunities and events, amazing poster sessions, and talks at the cutting-edge of the field. There were exciting new instrument reveals—Astral Zoom, timsOmni, timsUltra AIP, ZenoTOF8600

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Natalie Turner @natalieturnerau.bsky.social · Jun 6

🌟 I am also incredibly grateful to be the recipient of a travel award from the Supporting Growth for Women in Science Fund from Scripps Research @scripps.edu ! 🎉
#WomenInSTEM #WomenInScience #ExtracellularVesicles #TeamMassSpec #proteomics #massspectrometry

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Natalie Turner @natalieturnerau.bsky.social · Jun 6

💡 This week I attended #ASMS2025 in Baltimore to present 'Deep proteome characterization unveils distinct secretory phenotypes of Wild Type and familial Alzheimer's Disease organoids'. Our findings shed light on how secretory differences may influence disease progression and biomarker discovery.

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Reposted by Natalie Turner

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · Jun 5

More insights into #glycoRNA, this time found within exosomes!

www.nature.com/articles/s41...

Extracellular exosomal RNAs are glyco-modified - Nature Cell Biology

Sharma, Jiao and colleagues report glycosylation of small RNAs within exosomes and propose a glycosylation-dependent mechanism for RNA targeting into exosomes, which may influence intercellular commun...

www.nature.com

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Natalie Turner @natalieturnerau.bsky.social · May 30

Heading to #ASMS2025 next week? Check out our talks and posters from the Yates lab!

See the poster below for details 😁👇

#proteomics
#extracellularvesicles
#massspec
#glycoproteomics

@jyates.bsky.social

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Natalie Turner @natalieturnerau.bsky.social · May 25

More like success rates are going to be impacted and yes probably the ability of reviewers to fulfil their duties to the best of their abilities. I can only imagine what utter chaos is engulfing all NIH grant-related processes right now. If there was ever a time to stand up for science, this is it.

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Natalie Turner @natalieturnerau.bsky.social · May 25

It’s no surprise given the current climate in the NIH… I fear things are only going to get worse 😬

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Reposted by Natalie Turner

Michael Baym @baym.lol · May 13

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

A screenshot of the termination notice showing "Outstanding Investigator Grants"

A screenshot of the termination notice with "This award is terminated effective the date of this award, due to unsafe antisemitic actions that suggest the institution lacks concern for the safety and wellbeing of Jewish students." highlighted

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Natalie Turner @natalieturnerau.bsky.social · May 7

😄