Nicolas Guyon
@nicolasguyon.bsky.social
Vetenskapsrådet Postdoctoral Fellow at @espciparispsl.bsky.social.
ex PhD in neuroscience in Carlén Lab at @ki.se.
➡️ https://faurelab.cnrs.fr/?page_id=857
ex PhD in neuroscience in Carlén Lab at @ki.se.
➡️ https://faurelab.cnrs.fr/?page_id=857
Pinned
Nicolas Guyon
@nicolasguyon.bsky.social
· Apr 21
The interpeduncular nucleus blunts the rewarding effect of nicotine
Nicotine activates the dopamine reward system to promote consumption and addiction,
but the brain has a natural brake to counteract it. Jehl, Ciscato, Vicq, Guyon, et al.
identified the interpeduncula...
www.cell.com
Super happy to see our new study, on how the interpeduncular nucleus (IPN) regulates nicotine reward, out today in @cp-neuron.bsky.social!
Using #chemogenetics, we @faurelab.bsky.social show that blocking IPN activation enhances VTA responses and increases nicotine's rewarding effect.
#neuroscience
Using #chemogenetics, we @faurelab.bsky.social show that blocking IPN activation enhances VTA responses and increases nicotine's rewarding effect.
#neuroscience
Reposted by Nicolas Guyon
A crucial point to keep in mind when considering automation: work is not about production and money, it's about care. Or at least it should be, if we take some distance with managerial brainwashing.
1/4
1/4
February 4, 2026 at 9:00 AM
A crucial point to keep in mind when considering automation: work is not about production and money, it's about care. Or at least it should be, if we take some distance with managerial brainwashing.
1/4
1/4
Reposted by Nicolas Guyon
Academics vying for a spot in Epstein‘s world. There are so many. I feel the need to make a thread, so I don’t keep confusing them. 1/
January 31, 2026 at 9:02 PM
Academics vying for a spot in Epstein‘s world. There are so many. I feel the need to make a thread, so I don’t keep confusing them. 1/
Reposted by Nicolas Guyon
New PhD alert! We'll be applying animal welfare ideas to look at how stress affects bees, looking at the effect on bee brains with @lenariab.bsky.social, and working with @sensibee.bsky.social developing new monitoring methods.
Please spread the word! #bees #PhD 🧪
www.findaphd.com/phds/project...
Please spread the word! #bees #PhD 🧪
www.findaphd.com/phds/project...
The effect of stress on pollinator behaviour at Newcastle University on FindAPhD.com
PhD Project - The effect of stress on pollinator behaviour at Newcastle University, listed on FindAPhD.com
www.findaphd.com
February 3, 2026 at 1:21 PM
New PhD alert! We'll be applying animal welfare ideas to look at how stress affects bees, looking at the effect on bee brains with @lenariab.bsky.social, and working with @sensibee.bsky.social developing new monitoring methods.
Please spread the word! #bees #PhD 🧪
www.findaphd.com/phds/project...
Please spread the word! #bees #PhD 🧪
www.findaphd.com/phds/project...
Reposted by Nicolas Guyon
« L’Europe doit faire face à son passé colonial si elle veut se rapprocher des pays du Sud »
« L’Europe doit faire face à son passé colonial si elle veut se rapprocher des pays du Sud »
Les pays anciennement colonisateurs doivent entendre les revendications mémorielles des pays en développement qui réclament des excuses et des réparations, explique Julien Bouissou dans sa chronique.
www.lemonde.fr
February 3, 2026 at 3:33 PM
« L’Europe doit faire face à son passé colonial si elle veut se rapprocher des pays du Sud »
Reposted by Nicolas Guyon
Journalists should start by questioning public figures who communicated with Epstein after 2008 and ask, "Why would you engage in communication with a convicted child sex offender? Do you think that sexual violence against children is somehow rationalizable if the perpetrator is white and wealthy?"
Many US and European politicians and opinion leaders made careers out of saying "immigrants" don't share "our values" on things like sexual violence. The same people who now rationalize or excuse people who maintained relationships with a man even after he was convicted of raping children.
February 1, 2026 at 5:32 PM
Journalists should start by questioning public figures who communicated with Epstein after 2008 and ask, "Why would you engage in communication with a convicted child sex offender? Do you think that sexual violence against children is somehow rationalizable if the perpetrator is white and wealthy?"
Reposted by Nicolas Guyon
#Geometric principles of #dendritic integration of excitation and inhibition in #cortical #neurons | Science Advances www.science.org/doi/10.1126/...
Geometric principles of dendritic integration of excitation and inhibition in cortical neurons
Selective activation of E and I receptors by two-color uncaging defines their geometrical interaction at the subdendritic level.
www.science.org
January 16, 2026 at 8:50 PM
#Geometric principles of #dendritic integration of excitation and inhibition in #cortical #neurons | Science Advances www.science.org/doi/10.1126/...
Our recent work on the prefrontal cortex was featured in @nautil.us.
Check out the article here: nautil.us/the-brain-mi...
@pierrelemerre.bsky.social @carlenlab.bsky.social @ki.se
Check out the article here: nautil.us/the-brain-mi...
@pierrelemerre.bsky.social @carlenlab.bsky.social @ki.se
The Brain Might Not Function Like We Thought It Did
The Brain Might Not Function Like We Thought It Did: Complex thought may be organized by connection, not anatomy.
nautil.us
January 31, 2026 at 10:47 AM
Our recent work on the prefrontal cortex was featured in @nautil.us.
Check out the article here: nautil.us/the-brain-mi...
@pierrelemerre.bsky.social @carlenlab.bsky.social @ki.se
Check out the article here: nautil.us/the-brain-mi...
@pierrelemerre.bsky.social @carlenlab.bsky.social @ki.se
Reposted by Nicolas Guyon
If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh
parisneuro.ovh
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience
parisneuro.ovh
January 28, 2026 at 9:54 PM
If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh
parisneuro.ovh
Reposted by Nicolas Guyon
An excellent, bone-chilling story about a cadre of online racists who stole genetic data from studies on children so they could make specious arguments for the innate inferiority of non-white people, it's embrace by Elon Musk/twitter & how the Trump administration might make it easier to do again.
Genetic Data From Over 20,000 U.S. Children Misused for ‘Race Science’
www.nytimes.com
January 24, 2026 at 3:03 PM
An excellent, bone-chilling story about a cadre of online racists who stole genetic data from studies on children so they could make specious arguments for the innate inferiority of non-white people, it's embrace by Elon Musk/twitter & how the Trump administration might make it easier to do again.
Reposted by Nicolas Guyon
Now online if anyone wants to read about acute effects or psilocin (active metabolite of psilocybin) in rat mPFC www.sciencedirect.com/science/arti...
January 22, 2026 at 7:29 PM
Now online if anyone wants to read about acute effects or psilocin (active metabolite of psilocybin) in rat mPFC www.sciencedirect.com/science/arti...
Reposted by Nicolas Guyon
Board of Peace - Season 1
January 24, 2026 at 7:45 AM
Board of Peace - Season 1
Reposted by Nicolas Guyon
A new comparative study of seven lizard species, including chameleons and bearded dragons, finds an ancient sleep rhythm conserved over millennia.
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
December 29, 2025 at 6:34 PM
A new comparative study of seven lizard species, including chameleons and bearded dragons, finds an ancient sleep rhythm conserved over millennia.
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
By Lauren Schenkman
www.thetransmitter.org/sleep/snoozi...
Reposted by Nicolas Guyon
⚠️ New paper alert and what a way to end 2025! 🎉
Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience.
Sleeping dragons 🦎 and functional ultrasound!
Read the full paper here: rdcu.be/eWJHb 1/8
Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience.
Sleeping dragons 🦎 and functional ultrasound!
Read the full paper here: rdcu.be/eWJHb 1/8
Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals
Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...
rdcu.be
December 29, 2025 at 4:17 PM
⚠️ New paper alert and what a way to end 2025! 🎉
Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience.
Sleeping dragons 🦎 and functional ultrasound!
Read the full paper here: rdcu.be/eWJHb 1/8
Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience.
Sleeping dragons 🦎 and functional ultrasound!
Read the full paper here: rdcu.be/eWJHb 1/8
Reposted by Nicolas Guyon
🇪🇺🇺🇸 “Donald Trump isn’t the problem, America is” says @davekeating.substack.com, arguing US-EU relations won’t improve when Trump leaves office.
More in #F24Debate ➡️ f24.my/BgrG
More in #F24Debate ➡️ f24.my/BgrG
January 22, 2026 at 8:24 PM
🇪🇺🇺🇸 “Donald Trump isn’t the problem, America is” says @davekeating.substack.com, arguing US-EU relations won’t improve when Trump leaves office.
More in #F24Debate ➡️ f24.my/BgrG
More in #F24Debate ➡️ f24.my/BgrG
Reposted by Nicolas Guyon
I mer än ett sekel har anatomiska kartor delat upp hjärnan i regioner utifrån strukturella variationer i vävnaden. Men speglar dessa indelningar verkligen hur hjärnan fungerar? En ny studie på möss från @ki.se tyder på att så ofta inte är fallet @carlenlab.bsky.social #forskning
tinyurl.com/2tznb2pf
tinyurl.com/2tznb2pf
Nya hjärnkartor utmanar traditionella beskrivningar av hjärnan
I mer än ett sekel har kartor av hjärnan baserats på hur vävnaden ser ut under mikroskop. Dessa anatomiska kartor delar upp hjärnan i regioner utifrån strukturella variationer i vävnaden. Men speglar ...
tinyurl.com
January 22, 2026 at 8:13 AM
I mer än ett sekel har anatomiska kartor delat upp hjärnan i regioner utifrån strukturella variationer i vävnaden. Men speglar dessa indelningar verkligen hur hjärnan fungerar? En ny studie på möss från @ki.se tyder på att så ofta inte är fallet @carlenlab.bsky.social #forskning
tinyurl.com/2tznb2pf
tinyurl.com/2tznb2pf
Reposted by Nicolas Guyon
Ripple oscillations are central for memory and sleep.
But ripple detection in humans remains challenging. Here we introduce a simulation approach in @natcomms.nature.com as common ripple detectors mainly pick up 1/f noise and not genuine oscillations
👇
www.nature.com/articles/s41...
#neuroskyence
But ripple detection in humans remains challenging. Here we introduce a simulation approach in @natcomms.nature.com as common ripple detectors mainly pick up 1/f noise and not genuine oscillations
👇
www.nature.com/articles/s41...
#neuroskyence
Aperiodic 1/f noise drives ripple activity in humans - Nature Communications
How aperiodic 1/f noise drives ripple activity in human brain and impacts on ripple detections is not fully understood. Here authors show that ripple detections should be driven by the 1/f noise, whic...
www.nature.com
January 21, 2026 at 6:57 PM
Ripple oscillations are central for memory and sleep.
But ripple detection in humans remains challenging. Here we introduce a simulation approach in @natcomms.nature.com as common ripple detectors mainly pick up 1/f noise and not genuine oscillations
👇
www.nature.com/articles/s41...
#neuroskyence
But ripple detection in humans remains challenging. Here we introduce a simulation approach in @natcomms.nature.com as common ripple detectors mainly pick up 1/f noise and not genuine oscillations
👇
www.nature.com/articles/s41...
#neuroskyence
Reposted by Nicolas Guyon
Join leading scientists for a 3.5-day #LakeConference discussion on: "The Neurobiology of Mental Health" at the level of genes, cell types, organoids, circuits, networks and brain systems. Learn more & apply by January 31: https://lakeconferences.org/conf/1ed63fdb-de0c-4a56-a8b3-1f72f93d30ea
January 12, 2026 at 10:28 PM
Join leading scientists for a 3.5-day #LakeConference discussion on: "The Neurobiology of Mental Health" at the level of genes, cell types, organoids, circuits, networks and brain systems. Learn more & apply by January 31: https://lakeconferences.org/conf/1ed63fdb-de0c-4a56-a8b3-1f72f93d30ea
Reposted by Nicolas Guyon
Activity-based maps of the prefrontal cortex in mice, presented in @natneuro.nature.com today, challenge classical descriptions of the brain. The new maps reveal functional territories that differ from traditional, tissue-based maps. #Neuroscience #Brain 🧪 news.ki.se/new-brain-ma...
New brain maps challenge traditional descriptions of the brain
For more than a century, maps of the brain have been based on how brain tissue looks under the microscope. These anatomical maps divide the brain into regions according to structural variations in the...
news.ki.se
January 20, 2026 at 6:14 PM
Activity-based maps of the prefrontal cortex in mice, presented in @natneuro.nature.com today, challenge classical descriptions of the brain. The new maps reveal functional territories that differ from traditional, tissue-based maps. #Neuroscience #Brain 🧪 news.ki.se/new-brain-ma...
It's out! Our new study (led by @pierrelemerre.bsky.social & @weltgeischt.bsky.social @carlenlab.bsky.social) challenges classical cytoarchitectonic borders in the prefrontal cortex, showing that connectivity better explains its functional organization.
Read the open-access paper here: rdcu.be/eZUkh
Read the open-access paper here: rdcu.be/eZUkh
January 20, 2026 at 4:16 PM
It's out! Our new study (led by @pierrelemerre.bsky.social & @weltgeischt.bsky.social @carlenlab.bsky.social) challenges classical cytoarchitectonic borders in the prefrontal cortex, showing that connectivity better explains its functional organization.
Read the open-access paper here: rdcu.be/eZUkh
Read the open-access paper here: rdcu.be/eZUkh
Reposted by Nicolas Guyon
📢 Open faculty position – Origins of Life
We have an opening in our section at the University of Geneva! 🧬🚀
SPREAD THE WORD
Apply here: jobs.unige.ch/www/wd_porta...
We have an opening in our section at the University of Geneva! 🧬🚀
SPREAD THE WORD
Apply here: jobs.unige.ch/www/wd_porta...
a woman says " would you like to join us " with her eyes closed
ALT: a woman says " would you like to join us " with her eyes closed
media.tenor.com
January 16, 2026 at 5:49 PM
📢 Open faculty position – Origins of Life
We have an opening in our section at the University of Geneva! 🧬🚀
SPREAD THE WORD
Apply here: jobs.unige.ch/www/wd_porta...
We have an opening in our section at the University of Geneva! 🧬🚀
SPREAD THE WORD
Apply here: jobs.unige.ch/www/wd_porta...
Reposted by Nicolas Guyon
"The time for passive consumption has expired. Every scholar should begin contributing their expertise to Wikipedia — not as charity, but as a core duty"
www.nature.com/articles/d41...
www.nature.com/articles/d41...
The academic community failed Wikipedia for 25 years — now it might fail us
Artificial-intelligence systems are feeding on Wikipedia without giving back, and academic indifference is threatening the survival of what is arguably the most widely used reference work on the plane...
www.nature.com
January 19, 2026 at 4:18 PM
"The time for passive consumption has expired. Every scholar should begin contributing their expertise to Wikipedia — not as charity, but as a core duty"
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Nicolas Guyon
If you’re a young PI (or senior postdoc) heading to FENS, this one’s for you! It’ll be a lot of fun—and honestly, I can’t think of a better moment in one’s career to have a strong peer network.
📣 Our website is live and registration is NOW OPEN for the Young PI Symposium 2026 - the day prior to FENS Barcelona!
Navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Check out our program and join us!
Navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Check out our program and join us!
Young PI Symposium 2026
Visit the post for more.
youngpisymposium2026.com
January 16, 2026 at 12:58 PM
If you’re a young PI (or senior postdoc) heading to FENS, this one’s for you! It’ll be a lot of fun—and honestly, I can’t think of a better moment in one’s career to have a strong peer network.
Reposted by Nicolas Guyon
🗓 The next round of #NCAMH funding is coming soon on 1 Feb 2026!
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
January 16, 2026 at 2:05 PM
🗓 The next round of #NCAMH funding is coming soon on 1 Feb 2026!
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
Reposted by Nicolas Guyon
Published in Cell, a new study shows that the immune system’s reaction to the common Epstein-Barr virus can ultimately damage the brain and contribute to multiple sclerosis, from a team @ki.se
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple
sclerosis, with T cell responses against ANO2 occurring in over half of patients.
These ANO2-specific T cells shar...
www.cell.com
January 14, 2026 at 8:54 PM
Published in Cell, a new study shows that the immune system’s reaction to the common Epstein-Barr virus can ultimately damage the brain and contribute to multiple sclerosis, from a team @ki.se
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Nicolas Guyon
📣First preprint of the lab📣 Did that really happen?😅
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Genetic sex of enteric neurons enables ovarian relaxin to gate maternal gut plasticity
Animals must align intestinal plasticity and feeding with reproductive state, yet the checkpoint that gates these adaptations is unknown. Here we show that an ovary-to-enteric-neuron axis gates the on...
www.biorxiv.org
January 11, 2026 at 3:32 PM
📣First preprint of the lab📣 Did that really happen?😅
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...