Fabrice Senger
@senger.bsky.social
Mechanobiology / Multi-cellular assemblies
Reposted by Fabrice Senger
A Comment discusses how commands, data, and metadata currently discarded by scientific instruments could be used to train AI systems to learn to conduct experiments. @henrypinkard.bsky.social @nilsnorlin.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The missing data for intelligent scientific instruments - Nature Methods
Most scientific instruments currently discard rich streams of commands, data and metadata from which AI systems could learn to conduct experiments with expert-level decision-making and troubleshooting...
www.nature.com
January 26, 2026 at 6:01 PM
A Comment discusses how commands, data, and metadata currently discarded by scientific instruments could be used to train AI systems to learn to conduct experiments. @henrypinkard.bsky.social @nilsnorlin.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Fabrice Senger
Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon.
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion | PNAS
Intracellular transport of macromolecules is crucial for the proper functioning of
most cellular processes. Although intracellular crowding is know...
www.pnas.org
January 26, 2026 at 9:42 AM
Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon.
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
Reposted by Fabrice Senger
and certainly in you Buzz!
Using micropatterning & thousands of hours on the microscope
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
January 25, 2026 at 11:04 AM
and certainly in you Buzz!
Reposted by Fabrice Senger
Huge congrats to @manuelthery.bsky.social and all the Cytomorpho lab. The "Living Architectures" performance at @museeorsay.bsky.social was breathtakingly beautiful
January 25, 2026 at 9:22 AM
Huge congrats to @manuelthery.bsky.social and all the Cytomorpho lab. The "Living Architectures" performance at @museeorsay.bsky.social was breathtakingly beautiful
Reposted by Fabrice Senger
Analyzing single-molecule dynamics with both complex types of motion and complex transition kinetics: Benchmarking of ExaTrack https://www.biorxiv.org/content/10.64898/2026.01.22.700663v1
January 25, 2026 at 4:46 AM
Analyzing single-molecule dynamics with both complex types of motion and complex transition kinetics: Benchmarking of ExaTrack https://www.biorxiv.org/content/10.64898/2026.01.22.700663v1
Reposted by Fabrice Senger
So excited to share the preprint with the bulk of my PhD work in the Beach @myosincity.bsky.social and Oakes @pwoakes.bsky.social Labs at Loyola University Chicago! We investigate the structure, recruitment, and function of septin networks around the nucleus. A thread:
doi.org/10.64898/202...
doi.org/10.64898/202...
doi.org
January 23, 2026 at 5:45 PM
So excited to share the preprint with the bulk of my PhD work in the Beach @myosincity.bsky.social and Oakes @pwoakes.bsky.social Labs at Loyola University Chicago! We investigate the structure, recruitment, and function of septin networks around the nucleus. A thread:
doi.org/10.64898/202...
doi.org/10.64898/202...
Reposted by Fabrice Senger
and here is a nice list of software you can use instead of USinans ones: disconnect.blog/getting-off-...
(and also, are there still some people that wants to go on holiday in the USA????)
(and also, are there still some people that wants to go on holiday in the USA????)
January 23, 2026 at 6:44 AM
and here is a nice list of software you can use instead of USinans ones: disconnect.blog/getting-off-...
(and also, are there still some people that wants to go on holiday in the USA????)
(and also, are there still some people that wants to go on holiday in the USA????)
Reposted by Fabrice Senger
Our work is finally published in @science.org Advances! 🎉
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
January 7, 2026 at 1:09 PM
Our work is finally published in @science.org Advances! 🎉
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
Reposted by Fabrice Senger
@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
January 20, 2026 at 10:24 AM
@marineluciano.bsky.social recreates intestinal Villi geometry by growing epithelial cells on wavy rolling substrates. Unexpected intrication of curvature effects is observed. Thanks to all! @caterinatomba.bsky.social @sgabriele.bsky.social @sciencesunige.bsky.social
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Fabrice Senger
How can structures at the vertex of 3 cells have effects at the tissue level?
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
January 18, 2026 at 2:08 PM
How can structures at the vertex of 3 cells have effects at the tissue level?
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
Join me, @laura-rustarazo.bsky.social, to explore how tricellular junctions (TCJs) act as local tension sensors and regulators of global tissue organization. 🧵⤵️ doi.org/10.1126/scie...
Reposted by Fabrice Senger
Tune in on 23. jan to hear about our work on smart microscopy:
🎉 New year, new registration link for the #EuroBioImaging #VirtualPub! Don't miss out on all of the great talks we have planned. Please visit our website for an overview & to register. 🔽
www.eurobioimaging.eu/our-events/v...
www.eurobioimaging.eu/our-events/v...
January 2, 2026 at 11:44 AM
Tune in on 23. jan to hear about our work on smart microscopy:
Reposted by Fabrice Senger
#art 🎨 | Quand l’art devient expérimental & que chaque spectateur devient 🧑🔬.
A l'occasion du spectacle 'Architectures vivantes’ du @museeorsay.bsky.social qui aura lieu les 24 et 25 janvier prochains, @manuelthery.bsky.social, directeur scientifique du projet revient sur cette expérimentation en 📽️
A l'occasion du spectacle 'Architectures vivantes’ du @museeorsay.bsky.social qui aura lieu les 24 et 25 janvier prochains, @manuelthery.bsky.social, directeur scientifique du projet revient sur cette expérimentation en 📽️
January 16, 2026 at 8:39 AM
#art 🎨 | Quand l’art devient expérimental & que chaque spectateur devient 🧑🔬.
A l'occasion du spectacle 'Architectures vivantes’ du @museeorsay.bsky.social qui aura lieu les 24 et 25 janvier prochains, @manuelthery.bsky.social, directeur scientifique du projet revient sur cette expérimentation en 📽️
A l'occasion du spectacle 'Architectures vivantes’ du @museeorsay.bsky.social qui aura lieu les 24 et 25 janvier prochains, @manuelthery.bsky.social, directeur scientifique du projet revient sur cette expérimentation en 📽️
Reposted by Fabrice Senger
Monolithic cell-on-memristor architecture enables wafer-scale integration of oscillatory chemoreceptors for bio-realistic gustatory chips.
go.nature.com/4qjiD1O
go.nature.com/4qjiD1O
Monolithic cell-on-memristor architecture enables wafer-scale integration of oscillatory chemoreceptors for bio-realistic gustatory chips - Nature Materials
The fabrication of conventional artificial chemoreceptors are difficult to scale up. Here a wafer scale cell-on-memristor chemoreceptive array is reported, allowing for self-powered biosensing and in ...
go.nature.com
January 16, 2026 at 1:01 PM
Monolithic cell-on-memristor architecture enables wafer-scale integration of oscillatory chemoreceptors for bio-realistic gustatory chips.
go.nature.com/4qjiD1O
go.nature.com/4qjiD1O
Reposted by Fabrice Senger
📯👨🚀 Calling all #bioimage analysis aficionados. #EZInput is out! We wanted to bring #ImageJ’s capacity to record settings to the #Python ecosystem 🐍. It is a declarative library for generating UIs that just work. Done with @guijacquemet.bsky.social lab
arxiv.org/abs/2601.08859 #ScientificComputing
arxiv.org/abs/2601.08859 #ScientificComputing
January 15, 2026 at 11:36 AM
📯👨🚀 Calling all #bioimage analysis aficionados. #EZInput is out! We wanted to bring #ImageJ’s capacity to record settings to the #Python ecosystem 🐍. It is a declarative library for generating UIs that just work. Done with @guijacquemet.bsky.social lab
arxiv.org/abs/2601.08859 #ScientificComputing
arxiv.org/abs/2601.08859 #ScientificComputing
Reposted by Fabrice Senger
Multiscale curvature modulates epithelial architecture and nuclear organization. https://www.biorxiv.org/content/10.64898/2026.01.12.698973v1
January 13, 2026 at 1:47 AM
Multiscale curvature modulates epithelial architecture and nuclear organization. https://www.biorxiv.org/content/10.64898/2026.01.12.698973v1
Reposted by Fabrice Senger
New JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation
Anne Müsch presents the key findings from their recent JCS paper with David Cohen and Francisco Lázaro-Diéguez.
journals.biologists.com/jcs/article/...
Anne Müsch presents the key findings from their recent JCS paper with David Cohen and Francisco Lázaro-Diéguez.
journals.biologists.com/jcs/article/...
JCS snapshot - Bile canaliculi formation is dependent on ECM–cell-cell junctional crosstalk.
YouTube video by The Company of Biologists
youtu.be
January 12, 2026 at 4:17 PM
New JCS snapshot - Bile canaliculi formation in primary hepatocytes requires α1β1 integrin-dependent adherens junction re-organisation
Anne Müsch presents the key findings from their recent JCS paper with David Cohen and Francisco Lázaro-Diéguez.
journals.biologists.com/jcs/article/...
Anne Müsch presents the key findings from their recent JCS paper with David Cohen and Francisco Lázaro-Diéguez.
journals.biologists.com/jcs/article/...
Reposted by Fabrice Senger
Available to read via #OpenAccess:
pubs.rsc.org/en/content/a...
Affordable, cleanroom-free millifluidic production of targeted lipid nanocarriers via additive manufacturing
Oscar Ces, James W. Hindley et al
@cesiboy.bsky.social @jwhindley.bsky.social
pubs.rsc.org/en/content/a...
Affordable, cleanroom-free millifluidic production of targeted lipid nanocarriers via additive manufacturing
Oscar Ces, James W. Hindley et al
@cesiboy.bsky.social @jwhindley.bsky.social
January 12, 2026 at 9:27 AM
Available to read via #OpenAccess:
pubs.rsc.org/en/content/a...
Affordable, cleanroom-free millifluidic production of targeted lipid nanocarriers via additive manufacturing
Oscar Ces, James W. Hindley et al
@cesiboy.bsky.social @jwhindley.bsky.social
pubs.rsc.org/en/content/a...
Affordable, cleanroom-free millifluidic production of targeted lipid nanocarriers via additive manufacturing
Oscar Ces, James W. Hindley et al
@cesiboy.bsky.social @jwhindley.bsky.social
will dig into WaveOrder as well
We are particular fans of DySTrack (www.biorxiv.org/content/10.6...) by @zimengwu33.bsky.social & Jonas Hartmann at UCL for live tracking of dynamic samples & WaveOrder (arxiv.org/abs/2412.097...) by @mattersoflight.bsky.social et al as a wave-optical framework for scalable biological microscopy 🐟🔬
📢Our latest #preprint list is now up on FocalPlane
In this list, we focus on new tools and techniques in imaging 🔬.
Let us know if you have any recommendations that we have missed.
focalplane.biologists.com/2026/01/09/m...
In this list, we focus on new tools and techniques in imaging 🔬.
Let us know if you have any recommendations that we have missed.
focalplane.biologists.com/2026/01/09/m...
January 12, 2026 at 11:14 AM
will dig into WaveOrder as well
i really love this one : doi.org/10.64898/202...
DySTrack: a modular smart microscopy tool for live tracking of dynamic samples on modern commercial microscopes
Advances in microscopy and bioimage analysis are enabling unprecedented quantitative observation of dynamic biological systems. Smart microscopy closes the loop by feeding back image-derived informati...
doi.org
January 12, 2026 at 11:07 AM
i really love this one : doi.org/10.64898/202...
With an ExM super res combo
Direct labeling of microtubule turnover reveals in-lattice repair and stabilization patterns in developing neurons https://www.biorxiv.org/content/10.64898/2026.01.11.698892v1
January 12, 2026 at 6:48 AM
With an ExM super res combo
Reposted by Fabrice Senger
I’m thrilled to share the first preprint from the Piacentino Lab @hopkinsmedicine.bsky.social! We show that developing inner ear requires a secreted lipid chaperone, APOD, working in a positive feedback loop to amplify FGF/MAPK signaling. 👂 #DevBio Check it out! www.biorxiv.org/content/10.6...
Lipid-mediated reinforcement of FGF/MAPK signaling enables robust otic placode specification
The formation of cranial placodes requires groups of ectodermal cells to interpret inductive signals in a robust and organized manner, yet how signaling responses are coordinated across a developing f...
www.biorxiv.org
January 8, 2026 at 10:56 PM
I’m thrilled to share the first preprint from the Piacentino Lab @hopkinsmedicine.bsky.social! We show that developing inner ear requires a secreted lipid chaperone, APOD, working in a positive feedback loop to amplify FGF/MAPK signaling. 👂 #DevBio Check it out! www.biorxiv.org/content/10.6...
Reposted by Fabrice Senger
For 15(!) years I’ve been teaching introductory #MRI to grad students, and struggled to find a textbook for a wide variety of backgrounds. I'm happy to share an online textbook I created, fully open source (including code for generating figures and plots shown):
larsonlab.github.io/MRI-educatio...
larsonlab.github.io/MRI-educatio...
Introduction to Principles of MRI — Principles of MRI
larsonlab.github.io
January 10, 2026 at 7:42 AM
For 15(!) years I’ve been teaching introductory #MRI to grad students, and struggled to find a textbook for a wide variety of backgrounds. I'm happy to share an online textbook I created, fully open source (including code for generating figures and plots shown):
larsonlab.github.io/MRI-educatio...
larsonlab.github.io/MRI-educatio...