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Reposted by Artem Ilin

Ryan Flynn @raflynn5.bsky.social · 1d

We’re excited to report work led by postdoc Jennifer Porat in the lab, finding that DNA accumulates on the surface of living cells and that the secreted extracellular protein DNASE1L3 can modulate its levels on B and T cells. With a new twist for ATAC-seq as well www.biorxiv.org/content/10.1...

DNASE1L3 surveils mitochondrial DNA on the surface of distinct mammalian cells

The extracellular space is a critical environment for discriminating self versus non-self nucleic acids and initiating the appropriate immune responses through signaling cascades to relay information ...

www.biorxiv.org

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Reposted by Artem Ilin

Timothy Bredy @twbredy.bsky.social · 3d

Nowadays, too many institutions thinking ‘if we build it they will come’ combined with a shortsighted research funding model, a saturated Phd training sector, bloated admin load, and a general decline in creativity. Tough times indeed!

Kevin J. CREATURE @kevinjkircher.com · 4d

Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.

sites.stat.columbia.edu

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Reposted by Artem Ilin

Camille Moore @camille-moore.bsky.social · 6d

Today I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization.
www.science.org/doi/10.1126/...

ATP-dependent remodeling of chromatin condensates reveals distinct mesoscale outcomes

Adenosine triphosphate (ATP)–dependent chromatin remodeling enzymes mobilize nucleosomes, but how such mobilization affects chromatin condensation is unclear. We investigate effects of two major remod...

www.science.org

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Reposted by Artem Ilin

Michael Clarke @mtclarke.bsky.social · 6d

Yes, yes, Europe has its benefits. Walkable cities. Cultural heritage. Amazing food. Little gun violence. Healthcare. Governments that are not shut down. But the number of website pop-ups asking one to accept cookies renders the continent pretty much unlivable.

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Artem Ilin @adc34.bsky.social · 7d

It feels great to close 3 powerpoints, 10 word documents and 57 browser tabs after submitting the grant😌

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Reposted by Artem Ilin

Emma R Andersson @anderssonlab.bsky.social · 12d

👩‍🔬👨‍💻 Postdoc recruitment! 👨‍🔬👩‍💻

Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.

🚨 Deadline Oct 1st!! 🚨

Please re-post and help us spread the word far and wide! ✈

ki.varbi.com/en/what:job/...

Postdoctoral studies in next generation single cell lineage tracing of skin (scholarship)

Do you want to contribute to top quality medical research? A postdoctoral scholarship is available in the lab of Emma R Andersson at the Department of Cell and Molecular Biology, Karolinska Institutet

ki.varbi.com

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Reposted by Artem Ilin

boehninglab @boehninglab.com · 14d

A single brain infusion of miRNA targeting CAG repeats slows the progression of Huntington's disease by 75% in patients. This is something that I never thought I would see in my lifetime. www.uniqure.com/investors-me...

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Artem Ilin @adc34.bsky.social · 17d

Kicked off a series on #Drosophila TE discovery and naming. The first post covers elements that predate the term "mobile element", and more. artemilin.dev/posts/te_nam...

Drosophila TE name origins, Part 1 – Postdoc Postpunk

artemilin.dev

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Daniel Alber @danielalber.bsky.social · 20d

A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis!

Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)

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Rita Rebollo @ritarebollo.bsky.social · 23d

Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky

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Artem Ilin @adc34.bsky.social · 24d

🧀🧀🧀‼️

Ákos T Kovács @evolvedbiofilm.bsky.social · 24d

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation

Penicillium solitum over 8 years in a cheese cave => green-to-white shift

@currentbiology.bsky.social from @benwolfe.bsky.social with @kellerlab.bsky.social

www.cell.com/current-biol...

Long-term monitoring of a North American cheese cave reveals mechanisms and consequences of fungal adaptation

Using a unique longitudinal sampling approach, Louw et al. demonstrate how a cheese-associated Penicillium population has adapted in an artisan cheese production facility in Vermont, USA. Adaptation i...

www.cell.com

Artem Ilin @adc34.bsky.social · 24d

The papers that I enjoyed reading this week, especially the second one:
artemilin.dev/posts/202509...

Paper Digest #1 – Postdoc Postpunk

artemilin.dev

Artem Ilin @adc34.bsky.social · 25d

This gorgeous fella landed on my knee last week when I was in Vienna, chilled for a bit, didn't mind me touching him at all and then disappeared. Can anyone help identify? I would say that his length wasn't exceeding 6-7 mm. #entomology

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Nature Portfolio @natureportfolio.nature.com · 26d

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

This is figure 2, which shows M. ibericus queens lay males from two different species.

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Reposted by Artem Ilin

Kranzusch Lab @kranzuschlab.bsky.social · Sep 5

Together with @soreklab.bsky.social, our labs discovered that the human cGAS-STING pathway evolved from ancient bacterial proteins in CBASS anti-phage defense

www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...

STING cyclic dinucleotide sensing originated in bacteria - Nature

Structures of prokaryotic homologues of STING permit the reconstruction of the evolutionary trajectory of its incorporation into metazoan innate immunity, and reveal a role for the conserved cGAS–STIN...

www.nature.com

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Artem Ilin @adc34.bsky.social · Sep 2

Oh, look, mr. "I climbed Kilimanjaro" came to brag🙄

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Artem Ilin @adc34.bsky.social · Sep 2

Hoher Dachstein, 2997 m, no sherpas, no oxygen. (Don't mind the cable car)

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Justin Blumenstiel @bdelloid.bsky.social · Aug 30

In all my obsession with RNA silencing, I realized I became blind to the significance of autoregulation of DNA transposons. Which is funny, because it was characterized in many ways by my Ph.D. advisor. From 2013: elifesciences.org/articles/00668

The autoregulation of a eukaryotic DNA transposon

A DNA transposon, or ‘jumping gene’, controls its amplification within a genome through a competition between the enzyme multimers that are responsible for its mobility.

elifesciences.org

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Reposted by Artem Ilin

Mikhail Spivakov @mspivakov.bsky.social · Jul 19

Translational research is digging for gold. Basic research is learning where and what to dig. The more funding is diverted to translation, the more we deplete the research ecosystem, driving the supplies of "gold" - immediately translatable findings and innovations - to unsustainably low levels.

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Artem Ilin @adc34.bsky.social · Aug 29

SETDB yourself🫦

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Artem Ilin @adc34.bsky.social · Aug 29

HDACreate your image💅🏻

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Artem Ilin @adc34.bsky.social · Aug 29

DNMT3Beauty

Carmelo Ferrai @carmeloferrai.bsky.social · Aug 27

@magnanilab.bsky.social

What a hell is that? 🤪

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Reposted by Artem Ilin

Amelia Cervera 🍉 @ameliacervera.bsky.social · Aug 18

#TEsky #RNAsky #RNAbiology

Cell - a Cell Press journal @cp-cell.bsky.social · Aug 6

Now online! Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation

Composite transposons with bivalent histone marks function as RNA-dependent enhancers in cell fate regulation

This study reveals that composite transposons with bivalent histone marks can serve as RNA-dependent enhancers, controlling key developmental and aging-related gene programs.

dlvr.it

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Reposted by Artem Ilin

John Holbein @johnholbein1.bsky.social · Aug 18

Climate models since the 1970s nailed it—most predicted global warming almost exactly as it happened.

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Artem Ilin @adc34.bsky.social · Aug 17

I don't know the exact number of Nobel Prize laureates who wrote cooking books, but here's a rösti recipe from Christiane Nüsslein-Volhard: artemilin.neocities.org/post/250817_nv

Postdoc Postpunk

artemilin.neocities.org

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