@jahoyle.bsky.social
Anti-Brexit, pro-EU. Ex-virologist interested in the long-term effects of Covid-19.
Reposted
Reposted
Not good to see the rise in p-tau181, a marker of brain inflammation tied to increased risk of Alzheimer's disease, in a prospective cohort (mean age 56 years) with #LongCovid and neurological symptoms
www.thelancet.com/journals/ebi...
www.thelancet.com/journals/ebi...
January 15, 2026 at 2:19 AM
Not good to see the rise in p-tau181, a marker of brain inflammation tied to increased risk of Alzheimer's disease, in a prospective cohort (mean age 56 years) with #LongCovid and neurological symptoms
www.thelancet.com/journals/ebi...
www.thelancet.com/journals/ebi...
Reposted
I would argue that all covid deaths up until this point could have been prevented. That figure is over 250k. The single most important fact is covid is airborne!
January 15, 2026 at 7:42 AM
I would argue that all covid deaths up until this point could have been prevented. That figure is over 250k. The single most important fact is covid is airborne!
Reposted
If long COVID leads to Alzheimer's
And 3% of Brits have long COVID
Surely a good public health policy right now would be to protect more people from getting covid, developing long COVID, and in turn Alzheimer's?
And 3% of Brits have long COVID
Surely a good public health policy right now would be to protect more people from getting covid, developing long COVID, and in turn Alzheimer's?
January 16, 2026 at 6:03 AM
If long COVID leads to Alzheimer's
And 3% of Brits have long COVID
Surely a good public health policy right now would be to protect more people from getting covid, developing long COVID, and in turn Alzheimer's?
And 3% of Brits have long COVID
Surely a good public health policy right now would be to protect more people from getting covid, developing long COVID, and in turn Alzheimer's?
Reposted
Reposted
#DuvetKnowItsChristmas My poor son and daughter-in-law have been relegated to the study this year because the room they normally sleep in is full (literally) of my other daughter-in-law-to-be’s wedding dress hanging up and I don’t dare touch it!
December 24, 2025 at 9:30 PM
#DuvetKnowItsChristmas My poor son and daughter-in-law have been relegated to the study this year because the room they normally sleep in is full (literally) of my other daughter-in-law-to-be’s wedding dress hanging up and I don’t dare touch it!
Reposted
“While some argue that COVID-19 could act as a compounding factor in [people susceptible to Parkinson’s], others suggest the possibility of Parkinsonian features emerging as a consequence of viral infection.”
🧠 Daily Feed of Brain Damage 🧠
My concerns about REM Behaviour Disorder are not eased by this finding
doi.org/10.1007/s443...
My concerns about REM Behaviour Disorder are not eased by this finding
doi.org/10.1007/s443...
The compounding roles of gut-immune-brain axis and COVID19 in manifestation of idiopathic Parkinson’s disease - Discover Immunity
Discover Immunity - Parkinson’s disease (PD), for long has been understood as a neurodegenerative disorder confined solely to the brain. It is now emerging as a systemic illness marked by...
doi.org
December 20, 2025 at 11:12 AM
“While some argue that COVID-19 could act as a compounding factor in [people susceptible to Parkinson’s], others suggest the possibility of Parkinsonian features emerging as a consequence of viral infection.”
Reposted
The Lib Dem group leader, @antonyhook.bsky.social accused Reform of “wanting to spend public money on a political apparatchik to tell them what to do. KCC is in a worsening financial state under Reform with the projected overspend now at £46m and rising”
www.theguardian.com/politics/202...
www.theguardian.com/politics/202...
Reform councillors in Kent condemned for spending thousands on political assistants
Party that pledged to cut waste and save money faces criticism after pushing through vote to employ advisers
www.theguardian.com
December 20, 2025 at 8:00 PM
The Lib Dem group leader, @antonyhook.bsky.social accused Reform of “wanting to spend public money on a political apparatchik to tell them what to do. KCC is in a worsening financial state under Reform with the projected overspend now at £46m and rising”
www.theguardian.com/politics/202...
www.theguardian.com/politics/202...
Reposted
Immunological sin: how a person’s earliest flu infections dictate life-long immunity www.nature.com/articles/d41...
Immunological sin: how a person’s earliest flu infections dictate life-long immunity
Researchers are striving to understand the impact a phenomenon known as original antigenic sin has on immunity to the virus.
www.nature.com
December 18, 2025 at 1:46 PM
Immunological sin: how a person’s earliest flu infections dictate life-long immunity www.nature.com/articles/d41...
Reposted
25% reduction in all cause mortality over 4 years for those vaccinated against covid, huge study.
Wow, this almost suggests covid is implicated in an unbelievable number of deaths. And that vaccinated people should wear respirators if they want to remain abled.
www.cidrap.umn.edu/covid-19/mrn...
Wow, this almost suggests covid is implicated in an unbelievable number of deaths. And that vaccinated people should wear respirators if they want to remain abled.
www.cidrap.umn.edu/covid-19/mrn...
mRNA COVID vaccines tied to drop in death rate for 4 years
www.cidrap.umn.edu
December 18, 2025 at 2:50 PM
25% reduction in all cause mortality over 4 years for those vaccinated against covid, huge study.
Wow, this almost suggests covid is implicated in an unbelievable number of deaths. And that vaccinated people should wear respirators if they want to remain abled.
www.cidrap.umn.edu/covid-19/mrn...
Wow, this almost suggests covid is implicated in an unbelievable number of deaths. And that vaccinated people should wear respirators if they want to remain abled.
www.cidrap.umn.edu/covid-19/mrn...
Reposted
Read the study and think about population level implications, remembering that the vast majority of people have been infected multiple times.
What are the possible long-term neurological sequelae?
What are the implications for societies now?
news.griffith.edu.au/2025/12/16/c...
What are the possible long-term neurological sequelae?
What are the implications for societies now?
news.griffith.edu.au/2025/12/16/c...
COVID-19 leaves a lasting mark on the human brain - Griffith News
COVID-19 does not just affect the respiratory system, but also significantly alters the brain in people who have fully recovered from the infectious
news.griffith.edu.au
December 16, 2025 at 11:10 AM
Read the study and think about population level implications, remembering that the vast majority of people have been infected multiple times.
What are the possible long-term neurological sequelae?
What are the implications for societies now?
news.griffith.edu.au/2025/12/16/c...
What are the possible long-term neurological sequelae?
What are the implications for societies now?
news.griffith.edu.au/2025/12/16/c...
Reposted
Generative AI. Eats its young.
Chefs kiss. The volume ‘Social, Ethical and Legal Aspects of Generative Al’ appears to teach you about hallucinations by having various fictitious references including to the non existent ‘Harvard AI Journal’
www.thetimes.com/article/8f7d...
www.thetimes.com/article/8f7d...
Publisher under fire after ‘fake’ citations found in AI ethics guide
A book published by Springer Nature includes dozens of questionable citations, including references to journals that do not exist
www.thetimes.com
December 14, 2025 at 7:56 PM
Generative AI. Eats its young.
Reposted
Just when I thought I couldn't admire the man more...
🎯 🎯 🎯 💯 💯 💯 👍 👍 👍
🎯 🎯 🎯 💯 💯 💯 👍 👍 👍
December 13, 2025 at 6:58 PM
Just when I thought I couldn't admire the man more...
🎯 🎯 🎯 💯 💯 💯 👍 👍 👍
🎯 🎯 🎯 💯 💯 💯 👍 👍 👍
Reposted
"The virus can lead to brain swelling, which can cause lasting damage, including blindness, deafness and intellectual disabilities..."
www.nytimes.com/2025/12/11/w...
www.nytimes.com/2025/12/11/w...
December 14, 2025 at 5:14 AM
"The virus can lead to brain swelling, which can cause lasting damage, including blindness, deafness and intellectual disabilities..."
www.nytimes.com/2025/12/11/w...
www.nytimes.com/2025/12/11/w...
Reposted
The shape of things to come? Excellent analysis of what happens when Reform take the reins.
www.theguardian.com/politics/202...
www.theguardian.com/politics/202...
Infighting, broken promises and insisting on the national anthem: what seven months of Reform UK in charge actually looks like
Nigel Farage’s party is gunning for power – so what is it like in the places where they’ve already got it? We embedded with Lancashire county council to find out what happens when rhetoric meets reali...
www.theguardian.com
December 13, 2025 at 9:38 AM
The shape of things to come? Excellent analysis of what happens when Reform take the reins.
www.theguardian.com/politics/202...
www.theguardian.com/politics/202...
Reposted
2. Watching the current scrambling response of many healthcare systems to H3N2 K, combined with the firmly embedded political and ideological resistance to masking, I can assure you all that if H5N1 goes human to human with a high CFR, we're in deep trouble as a species.
/end
/end
December 13, 2025 at 12:34 PM
2. Watching the current scrambling response of many healthcare systems to H3N2 K, combined with the firmly embedded political and ideological resistance to masking, I can assure you all that if H5N1 goes human to human with a high CFR, we're in deep trouble as a species.
/end
/end
Reposted
YES YES YES thank you @georgemonbiot.bsky.social 🙏
😩AT LAST someone rasiing the alarm about what Europe's plummeting brith rates really mean!!
"In reality, without immigration there will be no Europe, no civilisation and no one left to argue about it."⚠️
It's. that. simple.
😩AT LAST someone rasiing the alarm about what Europe's plummeting brith rates really mean!!
"In reality, without immigration there will be no Europe, no civilisation and no one left to argue about it."⚠️
It's. that. simple.
December 12, 2025 at 10:22 AM
YES YES YES thank you @georgemonbiot.bsky.social 🙏
😩AT LAST someone rasiing the alarm about what Europe's plummeting brith rates really mean!!
"In reality, without immigration there will be no Europe, no civilisation and no one left to argue about it."⚠️
It's. that. simple.
😩AT LAST someone rasiing the alarm about what Europe's plummeting brith rates really mean!!
"In reality, without immigration there will be no Europe, no civilisation and no one left to argue about it."⚠️
It's. that. simple.
Reposted
What Steve said. There has never been a study in which high-quality, well-fitting masks were actually WORN that did not show a significant impact on disease transmission. Many mask studies failed to take account of post-allocation confounders (non-adherence + non-mask people choosing to mask).
So, to those who say "masks don't work", cite the flawed Cochrane report, insist upon an unfeasible RCT, accuse folks of panic, and undermine public health on social and mainstream media during a flu/RSV epidemic...
1. Seasonal viruses may be "normal", but they do immense harm.
1. Seasonal viruses may be "normal", but they do immense harm.
December 12, 2025 at 11:26 AM
What Steve said. There has never been a study in which high-quality, well-fitting masks were actually WORN that did not show a significant impact on disease transmission. Many mask studies failed to take account of post-allocation confounders (non-adherence + non-mask people choosing to mask).
Reposted
So, to those who say "masks don't work", cite the flawed Cochrane report, insist upon an unfeasible RCT, accuse folks of panic, and undermine public health on social and mainstream media during a flu/RSV epidemic...
1. Seasonal viruses may be "normal", but they do immense harm.
1. Seasonal viruses may be "normal", but they do immense harm.
December 12, 2025 at 11:07 AM
So, to those who say "masks don't work", cite the flawed Cochrane report, insist upon an unfeasible RCT, accuse folks of panic, and undermine public health on social and mainstream media during a flu/RSV epidemic...
1. Seasonal viruses may be "normal", but they do immense harm.
1. Seasonal viruses may be "normal", but they do immense harm.
Reposted
Reposted
#Medsky🧪 #IDsky #immunosky #Publichealth This study found that the accelerated #epigenetic aging in #COVID patients is primarily driven by immune dysregulation rather than the body's intrinsic aging processes.
DNA methylation-based epigenetic clocks highlight immune-driven aging acceleration in COVID-19 across diverse populations - Biogerontology
The SARS-CoV-2 pandemic has affected millions worldwide, with aging being a key risk factor for severe disease outcomes. This study examines the rate of epigenetic aging, as measured by DNA methylatio...
link.springer.com
December 9, 2025 at 7:20 AM
#Medsky🧪 #IDsky #immunosky #Publichealth This study found that the accelerated #epigenetic aging in #COVID patients is primarily driven by immune dysregulation rather than the body's intrinsic aging processes.
Reposted
“Children of COVID-infected mothers were diagnosed with neurodevelopmental conditions by age 3 at nearly twice the rate of those born to moms who did not get COVID, the study found. Boys were also more likely to be diagnosed than girls.”
www.post-gazette.com/news/health/...
www.post-gazette.com/news/health/...
COVID infection during pregnancy linked to neurodevelopmental issues in study
Testing positive for COVID-19 during pregnancy has been linked to a greater risk of the parent’s child having neurodevelopmental problems, research...
www.post-gazette.com
December 9, 2025 at 12:09 AM
“Children of COVID-infected mothers were diagnosed with neurodevelopmental conditions by age 3 at nearly twice the rate of those born to moms who did not get COVID, the study found. Boys were also more likely to be diagnosed than girls.”
www.post-gazette.com/news/health/...
www.post-gazette.com/news/health/...
Reposted
🔴230,000 Deaths and the ‘Calculated Silence’ of the Medical Establishment About the COVID Inquiry
The Covid Inquiry Report is a devastating critique of the medical establishment which led the UK to the worst public health disaster in a century, argues Anthony Costello
The Covid Inquiry Report is a devastating critique of the medical establishment which led the UK to the worst public health disaster in a century, argues Anthony Costello
230,000 Deaths and the ‘Calculated Silence’ of the Medical Establishment About the COVID Inquiry
The Covid Inquiry Report is a devastating critique of the medical establishment which led the UK to the worst public health disaster in a century, argues Anthony Costello
www.bylinesupplement.com
November 26, 2025 at 5:15 PM
🔴230,000 Deaths and the ‘Calculated Silence’ of the Medical Establishment About the COVID Inquiry
The Covid Inquiry Report is a devastating critique of the medical establishment which led the UK to the worst public health disaster in a century, argues Anthony Costello
The Covid Inquiry Report is a devastating critique of the medical establishment which led the UK to the worst public health disaster in a century, argues Anthony Costello
Reposted
Little reminder of Farage's pro Putin tendencies....
Hopefully some media outlets may take up @eddavey.libdems.org.uk 's suggestions to probe Mr Farage a bit more on this.
Is Farage saying he chose to support the wishes of a hostile foreign govt for free? 😲
#ReleaseTheRussiaReport
Hopefully some media outlets may take up @eddavey.libdems.org.uk 's suggestions to probe Mr Farage a bit more on this.
Is Farage saying he chose to support the wishes of a hostile foreign govt for free? 😲
#ReleaseTheRussiaReport
November 25, 2025 at 12:04 PM
Little reminder of Farage's pro Putin tendencies....
Hopefully some media outlets may take up @eddavey.libdems.org.uk 's suggestions to probe Mr Farage a bit more on this.
Is Farage saying he chose to support the wishes of a hostile foreign govt for free? 😲
#ReleaseTheRussiaReport
Hopefully some media outlets may take up @eddavey.libdems.org.uk 's suggestions to probe Mr Farage a bit more on this.
Is Farage saying he chose to support the wishes of a hostile foreign govt for free? 😲
#ReleaseTheRussiaReport