khannakm.bsky.social
Kamal M Khanna
@khannakm.bsky.social
100 followers 170 following 7 posts
Scientist/Immunologist at NYU school of Medicine. http://khannalab.weebly.com/kamal-m-khanna.html
khannalab.weebly.com
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khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 25
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now [email protected] #macrophages
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
7 17
Reposted by Kamal M Khanna
payalyokota.bsky.social
Payal Yokota @payalyokota.bsky.social · Aug 3
Check out this beautiful paper from Isaac Chiu lab, with some contributions from our lab.

www.science.org/doi/10.1126/...

@khannakm.bsky.social
Vagal TRPV1+ sensory neurons protect against influenza virus infection by regulating lung myeloid cell dynamics
TRPV1+ neurons facilitate host survival from flu infection by controlling viral spread, myeloid cell responses, and immunopathology.
www.science.org
2 6
Reposted by Kamal M Khanna
payalyokota.bsky.social
Payal Yokota @payalyokota.bsky.social · Jun 9
Brilliant and paradigm shaking new story by Vishwa Deep Dixit's team out this month @naturemetabolism.bsky.social -"Cysteine depletion triggers adipose tissue thermogenesis and weight loss". Congratulations to Deep, Aileen and the entire team on this important work. 🤯
www.nature.com/articles/s42...
Cysteine depletion triggers adipose tissue thermogenesis and weight loss - Nature Metabolism
The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.
www.nature.com
1 6
Reposted by Kamal M Khanna
payalyokota.bsky.social
Payal Yokota @payalyokota.bsky.social · Jun 7
Check out the latest review article from #TeamKhanna superstars Eduardo Bernier and recent alumni Dr. Eric Bartnicki.

Macrophages: sentinels, warriors, and healers
Free Link:
academic.oup.com/hmg/advance-...

@khannakm.bsky.social
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khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Jun 7
Our latest review on macrophages Macrophages: sentinels, warriors, and healers url:https://academic.oup.com/hmg/article-abstract/doi/10.1093/hmg/ddaf087/8158008

academic.oup.com/hmg/advance-...
Macrophages: sentinels, warriors, and healers
Abstract. Macrophages are versatile innate immune cells that act as sentinels, warriors, and healers in virtually every tissue. This review synthesizes cur
academic.oup.com
8 22
Reposted by Kamal M Khanna
lozanzi.bsky.social
Ivan Zanoni @lozanzi.bsky.social · Jun 4
#WeAreWhatWeEat! #EveryCellIsAnImmuneCell! Dixit, Lee &co show @natmetabolism.nature.com that caloric restriction depletes cysteines, driving weight loss & browning of white adipose tissue via sympathetic nervous system-derived noradrenaline signaling, reversing metabolic inflammation in obese mice!
Cysteine depletion triggers adipose tissue thermogenesis and weight loss - Nature Metabolism
The authors describe how reduced dietary availability and systemic loss of cysteine leads to adipose tissue browning and rapid weight loss in mice and humans.
doi.org
2 7
Reposted by Kamal M Khanna
payalyokota.bsky.social
Payal Yokota @payalyokota.bsky.social · May 13
Thank you for highlighting this preview of our work by Drs. Rothlin and Ghosh at @yalesph.bsky.social.

What a delight to see this.. 🥹

@khannakm.bsky.social @yeungadventures.bsky.social
labwaggoner.bsky.social
Waggoner Lab @labwaggoner.bsky.social · May 13
Lung nerve- and airway-associated macrophage response to type I interferon limits SARS-CoV-2 spread, inflammation, lung injury, and mortality
@cp-immunity.bsky.social preview
cell.com/immunity/ful...
of
cell.com/immunity/ful...
You know my NAMs
The critical immunoregulatory function of the lung nerve- and airway-associated macrophages (NAMs) is increasingly becoming evident. In this issue of Immunity, Yeung et al. report that NAMs’ response ...
cell.com
2 3
Reposted by Kamal M Khanna
cp-immunity.bsky.social
Immunity @cp-immunity.bsky.social · May 13
May issue is online! Explore reviews on the #neuroimmune axis! The beautiful cover was designed by Ella Marushchenko, working with @jonykipnis.bsky.social. A brain encased in a walnut shell that is cracking open symbolizes our growing understanding of #neuroimmunology www.cell.com/immunity/iss...
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khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · May 4
Indeed! Great job Mimi!
payalyokota.bsky.social
Payal Yokota @payalyokota.bsky.social · May 4
Yay!!! #TeamKhanna superstar Mimi Kostoska presenting her work on splenic CD169+ macrophages #aai2025 @khannakm.bsky.social #Khannalab #RTM #staphaureus

Thanks for the picture, @yeungadventures.bsky.social
yeungadventures.bsky.social
Stephen T Yeung, PhD 🏳️‍🌈 @yeungadventures.bsky.social · May 4
Beautiful talk on #cd169 #macrophages in response to #staphaureus by PhD student Mimi Kostoska from Khanna Lab @nyulangone.bsky.social so excited to see this work come progressing! @aai.org #immunology2025 #aai2025
khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 30
Congratulations John!
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Reposted by Kamal M Khanna
nyumedpostdocs.bsky.social
NYU Grossman School of Medicine Postdoctoral Affairs @nyumedpostdocs.bsky.social · Apr 29
🫁"Lung Immune Cell Type ‘Quietly’ Controls Inflammation in COVID-19". Congrats @payalyokota.bsky.social, @khannakm.bsky.social, and colleagues!

nyulangone.org/news/lung-im...
Lung Immune Cell Type ‘Quietly’ Controls Inflammation in COVID-19
NYU Langone study shows a type of immune cell in the lungs may help prevent inflammation from spiraling out of control during COVID-19. Learn more.
nyulangone.org
3 5
Reposted by Kamal M Khanna
sbkoralov.bsky.social
sbkoralov.bsky.social @sbkoralov.bsky.social · Apr 28
www.cbsnews.com/news/scienti...

I wish this was sensationalized or exaggerated - but the impact on US biomedical research outlined in this report is, unfortunately, very much real.
Scientists fear Trump administration cuts to NIH could impact the health of Americans for generations
Former National Institutes of Health Director Dr. Francis Collins, who abruptly left his NIH research lab in February, fears aggressive downsizing could impact Americans' health.
www.cbsnews.com
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Reposted by Kamal M Khanna
marionpepper.bsky.social
Marion Pepper @marionpepper.bsky.social · Apr 27
Please watch tonight’s important episode of “60 minutes” focused on the impacts of reductions to the NIH budget and workforce featuring a UW Immunology graduate student.

www.youtube.com/watch?v=noyS...
NIH | Sunday on 60 Minutes
YouTube video by 60 Minutes
www.youtube.com
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khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 27
Thank you Sergei
khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 27
Fantastic and important work @ikinglab.bsky.social
ikinglab.bsky.social
King Lab at McGill University @ikinglab.bsky.social · Apr 22
I am very excited to share our article on IFNg, stroma and disease tolerance during intestinal helminth infection published today in Cell. This work was lead by the amazing @susanwestfall.bsky.social and supported by many international collaborators.

www.sciencedirect.com/science/arti...
A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection
Type 1 immunity mediates host defense through pathogen elimination, but whether this pathway also impacts tissue function is unknown. Here, we demonst…
www.sciencedirect.com
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Reposted by Kamal M Khanna
bsheridanlab.bsky.social
Brian Sheridan Lab @bsheridanlab.bsky.social · Apr 26
Another great study from the @khannakm.bsky.social lab! Disease tolerance to limit Pathology in mucosal tissues
khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 25
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now [email protected] #macrophages
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
1 1 1
khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 26
Thanks Brian!
Reposted by Kamal M Khanna
ikinglab.bsky.social
King Lab at McGill University @ikinglab.bsky.social · Apr 26
Host defense involves both resistance and disease tolerance, a concept elegantly demonstrated in lung viral infection by @yeungadventures.bsky.social @payalyokota.bsky.social @khannakm.bsky.social and colleagues. Spread the word!!
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Reposted by Kamal M Khanna
mayerbarber.bsky.social
Kat Mayer-Barber,PhD @mayerbarber.bsky.social · Apr 26
So cool!

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful...
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
1 3 17
Reposted by Kamal M Khanna
cp-immunity.bsky.social
Immunity @cp-immunity.bsky.social · Apr 25
Online now: Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated macrophages (NAMs) in mitigating SARS-CoV-2 pathogenesis. NAMs regulate viral spread and inflammation through type I interferon signaling, revealing their critical function in disease tolerance and potential as therapeutic targets for respiratory viral infections.
dlvr.it
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khannakm.bsky.social
Kamal M Khanna @khannakm.bsky.social · Apr 25
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now [email protected] #macrophages
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
7 17
Reposted by Kamal M Khanna
payalyokota.bsky.social
Payal Yokota @payalyokota.bsky.social · Apr 25
Excited to share our latest study
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...
www.cell.com
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