Lightnews — Scholar-powered news

Silvia Anderle @silvia-anderle.bsky.social · Aug 6

Thank you Lewis 😄

Silvia Anderle @silvia-anderle.bsky.social · Aug 5

Thank you Kira, I hope you find the read interesting 😊

Reposted by Silvia Anderle

UK Dementia Research Institute @ukdri.ac.uk · Aug 4

Delighted to welcome a new Group Leader to our flagship vascular dementia research centre with @thebhf.bsky.social 🎉👏

Prof Catherine Hall @cathnaledi.bsky.social and her team will examine how changes in blood flow & oxygen supply drive the onset of vascular dementia & Alzheimer’s👉 buff.ly/gyouoEV

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Silvia Anderle @silvia-anderle.bsky.social · Aug 5

Thanks Axel! 😊

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Silvia Anderle @silvia-anderle.bsky.social · Aug 5

Delighted to share our latest review in Nature Reviews Neuroscience!
We examine the growing evidence that vascular dysfunction plays a key role in cognitive decline in ageing and dementia, and argue that preserving/restoring CBF should be central to future therapies.
www.nature.com/articles/s41...

The vascular contribution to cognitive decline in ageing and dementia - Nature Reviews Neuroscience

Growing evidence suggests that reduced cerebral blood flow contributes to cognitive decline in ageing and dementia. Attwell and colleagues discuss the underlying mechanisms and functional consequences...

www.nature.com

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Reposted by Silvia Anderle

UK Dementia Research Institute @ukdri.ac.uk · Jun 24

We're excited to welcome a new Group Leader to our vascular dementia research centre with the BHF🎉👏

Prof Susanne van Veluw's research focuses on cerebral amyloid angiopathy, where amyloid beta accumulates in the walls of the brain's blood vessels👉https://buff.ly/rNxxNRz

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Reposted by Silvia Anderle

Kira Shaw @kirasha.bsky.social · Jul 16

Come and join us in Manchester... We are looking for candidates interested in vascular health and neurodegeneration. This project is specifically exploring how menopause may increase Alzheimer's risk.
We also have a postdoc position available: www.jobs.manchester.ac.uk/Job/JobDetai...

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Reposted by Silvia Anderle

Rikesh Rajani @rikeshrajani.bsky.social · Jul 10

The Rajani Lab is hiring! We are looking for a postdoc to join us at @ukdri.ac.uk @edinburgh-uni.bsky.social to investigate neuronal activity and white matter changes in vascular dementia.

Apply here 👇
bit.ly/44AFJHx

Research Fellow

We are looking for a postdoctoral Research Fellow to join the Rajani Lab as part of the new national BHF-UK DRI Centre for Vascular Dementia Research.

bit.ly

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Reposted by Silvia Anderle

Axel Montagne @axelmontagne.bsky.social · Jul 22

🚨 Review Alert

*Walking on the tightrope: the shared roles of the bridging pericytes in the brain*

Congratulations Audrey Chagnot!! 🥳

Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊

www.frontiersin.org/journals/cel...

Frontiers | Walking on the tightrope: the shared roles of the bridging pericytes in the brain

The vasculature of the central nervous system (CNS) is a highly specialized structure that delivers oxygen and nutrients to energy-demanding neural cells whi...

www.frontiersin.org

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Reposted by Silvia Anderle

Hajime Hirase @hajimehirase.bsky.social · Mar 19

Vittani, Lee, Wang, Hiraoka, et al.
KI mouse expressing red fluorescent blood
In situ SpyTag/Catcher attachment of biosensor
ECS SpyCatcher to capture BBB leak
doi.org/10.1101/2025...
We hope this method is useful to a wide range of the biology community.

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Reposted by Silvia Anderle

Axel Montagne @axelmontagne.bsky.social · Mar 14

www.ahajournals.org/doi/abs/10.1...

Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations | Stroke

BACKGROUND: More than half of patients with ischemic stroke experience futile reperfusion, increasing the risk of death and disabilities despite a successful recanalization. The reason behind this is ...

www.ahajournals.org

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Reposted by Silvia Anderle

Baptiste Lacoste @blacoste.bsky.social · Mar 14

www.nature.com/articles/s41...

Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter - Nature Neuroscience

White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in cerebellar WM, suggestin...

www.nature.com

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Reposted by Silvia Anderle

Catherine Hall @cathnaledi.bsky.social · Feb 13

@physoc.bsky.social has a starter pack of physiologists. Hooray!! go.bsky.app/2KU1XD6

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Silvia Anderle @silvia-anderle.bsky.social · Feb 13

Welcome! 🥳♥️

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Silvia Anderle @silvia-anderle.bsky.social · Jan 30

My first first author paper is finally out! 🎉 Go check it out or read the fantastic blue-torial put together by @cathnaledi.bsky.social 😍 hope you enjoy the read and let us know what you think! 😊

Catherine Hall @cathnaledi.bsky.social · Jan 30

New paper led by @silvia-anderle.bsky.social

Lifestyle matters for genetic Alzheimer’s disease risk: APOE4 reduces neurovascular function most in an already-stressed system, when neurons are active and mice do less exercise.

I'll tell you all about it! 🧪 #neuroscience #alzheimers

rdcu.be/d74uh

APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice

Communications Biology - Lifestyle matters for genetic Alzheimer’s disease risk: In vivo imaging of mouse blood vessels and neurons shows that APOE4 reduces neurovascular function most in an...

rdcu.be

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Silvia Anderle @silvia-anderle.bsky.social · Jan 30

Thank you Craig 🙌🏼

Reposted by Silvia Anderle

Osama Harraz @osamaharraz.bsky.social · Jan 11

Outstanding and inspiring study!

Norepinephrine (NE)-mediated slow vasomotion drives glymphatic clearance during sleep

www.cell.com/cell/fulltex...

- NE release drives slow vasomotion in NREM sleep

- NE oscillations trigger opposing changes in blood/CSF volumes & predicts glymphatic clearance

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Reposted by Silvia Anderle

Science Magazine @science.org · Dec 17

Infection with #SARSCoV2 has highlighted how altered endothelial functions contribute to multiorgan health effects during the acute phase of #COVID19 and potentially to the longer-term consequences associated with #LongCovid.

Learn more in a new #SciencePerspective:

Endothelial inflammation in COVID-19

Disrupted endothelial function underlies the multiorgan complications of COVID-19

scim.ag

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Reposted by Silvia Anderle

Jomsgon @jomsgon.bsky.social · Dec 12

Some of our work: "Impairment of neurovascular coupling in the hippocampus due to decreased nitric oxide bioavailability supports early cognitive dysfunction in type 2 diabetic rats"

#neurovascular #cognition
#nitricoxide #diabetes

www.sciencedirect.com/science/arti...

Impairment of neurovascular coupling in the hippocampus due to decreased nitric oxide bioavailability supports early cognitive dysfunction in type 2 diabetic rats

Numerous epidemiological and preclinical studies have established a strong correlation between type 2 diabetes (T2DM) and cognitive impairment and T2D…

www.sciencedirect.com

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Reposted by Silvia Anderle

Lisi Flores-Aguilar @lisi-fa.bsky.social · Dec 11

🎉A bit late to the party, but happy to be joining this community!

💫The Down syndrome and Alzheimer’s disease PIA has put together a webinar on cerebrovascular pathology in DS and AD. Please join us on Zoom on Friday 13th, 10:30 am PST, 12:30 CT USA.

✏️Register here: alz-org.zoom.us/webinar/regi...

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Silvia Anderle @silvia-anderle.bsky.social · Dec 11

I guess it was about time to ditch X.
Hello Bluesky! 👋🏼

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Reposted by Silvia Anderle

Søren Grubb @sorengrubb.bsky.social · Nov 30

For more on this subject, follow the researchers in the following starter packs:

Pericytes: go.bsky.app/GhVdxzC

Blood-brain barrier & neurovasculature: go.bsky.app/RB6RXKy

Cardiovascular research: go.bsky.app/SgaGkv5

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Reposted by Silvia Anderle

Søren Grubb @sorengrubb.bsky.social · Nov 30

For more on this subject, follow the researchers in the following starter packs:

Pericytes: go.bsky.app/GhVdxzC

Blood-brain barrier & neurovasculature: go.bsky.app/RB6RXKy

Cardiovascular research: go.bsky.app/SgaGkv5

Neuroimmunology: go.bsky.app/Eaua5Jk

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