Lightnews — Scholar-powered news

Reposted by Micah Etter, MD

Richard Choi, DO, FNCS @rkchoi.bsky.social · 24d

1/ 👋 there #neurotwitter #neurocritcare, as part of my @neurocritcarej #SoMeAmbassador role, today we will be breaking down the following article:

Prospective Trial of Cerebrospinal Fluid Filtration After Aneurysmal Subarachnoid Hemorrhage via Lumbar Catheter Extension (PILLAR-XT)

Neurocritical Care - There is a growing consensus that blood in the cerebrospinal fluid (CSF) is deleterious to outcomes in patients with aneurysmal subarachnoid hemorrhage. The extracorporeal...

link.springer.com

1 2 5

Reposted by Micah Etter, MD

Bryan Carmody @jbcarmody.bsky.social · Sep 11

On September 24, ERAS will open to programs. Which means applicants have only 2 weeks left to decide which programs to signal.

And if you want to know how to allocate your signals in the most effective manner possible, I’ve got something for you:

thesheriffofsodium.com/2025/09/10/t...

The Applicant’s Guide to Strategic Preference Signaling

Whenever I discuss preference signaling on social media, one of the first replies is always “Wait – what’s that?” In the olden days, when an applicant was interested in a particular residency…

thesheriffofsodium.com

3 9

Reposted by Micah Etter, MD

Richard Choi, DO, FNCS @rkchoi.bsky.social · Sep 3

1/ Hello #medsky #neurosky #neurocritcare #FOAMEd have another brief case that I wanted to discuss with you and see if maybe you can learn something new or reinforce old knowledge!

1 4 7

Micah Etter, MD @mettermd.bsky.social · Sep 1

🚨NEW RELEASE🚨

🔍Daily neurology connections, anyone?

neuroconnections.me has launched with a free, fun micro-learning puzzle game every day! Still the initial release so let me know if you spot any bugs.🐛

Play and learn here: neuroconnections.me

#Neurology #MedEd

🧠 NeuroConnections

NeuroConnections.me

1

Micah Etter, MD @mettermd.bsky.social · Aug 26

🚨New thing release announcement! 🚨

StrokeBot.me is a free stroke code simulator for trainees! Practice workflows, interventions, disposition calls, and more!

This is just the initial release so bugs are expected and updates ongoing! Enjoy!

#Neurology #MedEd

StrokeBot.me - Acute Stroke Simulator

StrokeBot.me

1

Reposted by Micah Etter, MD

Eric Topol @erictopol.bsky.social · Aug 10

Could a metal ion supplement that cost pennies per day protect from Alzheimer's disease?
erictopol.substack.com/p/lithium-an...

lithium ion trapped by beta-amyloid and the way to get around it

16 49 220

Reposted by Micah Etter, MD

😱🩸Spooky SpectreKILLoquy 🎃🔪 @caulimovirus.bsky.social · Oct 13

Bottle of synthroid next to simple anatomical drawing of thyroid gland

Bottle of chrome next to brighter illustration of thyroid gland

Packet of liotrix next to positively glowing illustration of thyroid gland

Bottle of armour thyroid next to cosmically significant illustration of thyroid gland

Pubmed headline “An outbreak of thyrotoxicosis caused by the consumption of bovine thyroid gland in ground beef” next extremely bright illustration of thyroid gland overlaying the pillars of creation nebula

3 6 37

Reposted by Micah Etter, MD

Richard Choi, DO, FNCS @rkchoi.bsky.social · Aug 6

1/ Hello #medsky #neurosky #neurocritcare #FOAMEd have a brief case that I wanted discuss with you and see if maybe you can learn something new or reinforce old knowledge!

1 2 4

Reposted by Micah Etter, MD

NEJM.org @nejm.org · Jul 24

A 50-year-old woman presented to the emergency department with a 10-day history of a throbbing headache that had suddenly started after she had felt a “pop” in her back. The headache worsened with upright positioning and improved with lying flat. 1/4

#MedSky

Image Challenge
What is the diagnosis?

Upper left: MRI of the brain showing diffuse pachymeningeal enhancement.
Lower left: A computed tomographic myelogram.
Right: MRI showing protrusion of the cerebellar tonsils into the foramen magnum (tonsillar ectopia), flattening of the pons with effacement of the prepontine cistern, and enlargement of the pituitary gland owing to increased blood flow.

3 6 14

Reposted by Micah Etter, MD

Anthony Lau, PharmD BCPS @alaurx.bsky.social · Jul 14

Case series w/ cumulative total n=110 pts support use of rivastigmine as alternative antidote to physostigmine for anticholinergic delirium. Both oral & transdermal formulations of rivastigmine may expedite recovery #medsky #EMsky #pharmsky #emimcc #FOAMed

👉 link.springer.com/article/10.1...

Just the facts: rivastigmine for the management of anticholinergic toxicity - Canadian Journal of Emergency Medicine

Canadian Journal of Emergency Medicine -

link.springer.com

2 9

Reposted by Micah Etter, MD

josh farkas 💊 @pulmcrit.bsky.social · Jul 6

OpenEvidence is generally very good, but it's occasionally horrifically wrong

One place it falls down a lot is drug allergy (where it's often too conservative)

There are NO absolute contraindications to acetylcysteine for acetaminophen OD

Reported "allergy" = anaphylactoid rxns... (#1/3) #EMIMCC

2 5 18

Reposted by Micah Etter, MD

brandon-beaber.bsky.social @brandon-beaber.bsky.social · Jun 29

You had MS even before you had symptoms. This study found increased absenteeism from work 6 years prior to diagnosis. jnnp.bmj.com/content/earl...

Prodromal phase of multiple sclerosis: evidence from sickness absence patterns before disease onset – a matched cohort study

Background We aimed to investigate the prodromal phase of multiple sclerosis (MS) by investigating annual sickness absence rates before MS onset. Methods A retrospective cohort study was conducted us...

jnnp.bmj.com

1 6 13

Reposted by Micah Etter, MD

Saskia Middeldorp @middeldorps.bsky.social · Jun 22

This is what we were waiting for. A direct comparison between apixaban and rivaroxaban for the treatment of acute VTE. Apixaban reduces bleeding risk in the first 3 months by >50%!

Practice changing investigator-initiated RCT.

#ISTH2025

4 37 73

Reposted by Micah Etter, MD

Braydon Dymm, MD @befast.bsky.social · Jun 15

Peer review is being transformed by AI, whether we like it or not.

From my own experience, most researchers are using it wrong… and that’s because no one’s talking about it! Let me share some ideas on how to harness its potential to improve scientific publishing.

A web-comic that says "A Simple Guide to Using AI in Peer Review" with one panel that says "Wrong Way" and the next panel says "Right Way."

1 1 3

Reposted by Micah Etter, MD

JAMA @jama.com · Jun 22

Herpes zoster vaccination eligibility reduced the probability of new dementia diagnoses, suggesting its potential preventive effect.

https://ja.ma/4lagSB6

Herpes Zoster Vaccination and Dementia Occurrence

10 20

Reposted by Micah Etter, MD

Pediatric Neurology @pedneurojournal.bsky.social · Jun 22

What is the prevalence of elevated opening pressure in children with Alexander Disease?

In the current issue of #pedneuro journal, Joung et al. explore this question through analysis of opening pressure, MRI and examination in a cohort of 43 patients.

Read Here: buff.ly/UrvyLjh

1 2

Reposted by Micah Etter, MD

josh farkas 💊 @pulmcrit.bsky.social · Jun 13

INDEX trial: CT perfusion wasn't adequate for evaluating brain death.

huge problem: they're using clinical exam as the gold standard

I think most patients classified as brain dead by CT perfusion but alive by exam were dead... #1/2

#EMIMCC #CCR25

1 2 6

Micah Etter, MD @mettermd.bsky.social · Jun 12

"Plasma p-tau217 reliably identified clinic patients with Alzheimer's"🆒

"definitive results in 86% of patients" 🆒

"Integration of plasma Aβ42 minimally improved diagnostic performance"🐟

"Plasma p-tau217 levels were increased in patients with kidney dysfunction"🫘

Diagnostic performance of plasma p‐tau217 and Aβ42/40 biomarkers in the outpatient memory clinic

INTRODUCTION Plasma biomarkers of Alzheimer's disease (AD) represent accessible alternatives to positron emission tomography (PET) and cerebrospinal fluid (CSF)-based biomarkers in well-characterize.....

alz-journals.onlinelibrary.wiley.com

1 3

Micah Etter, MD @mettermd.bsky.social · May 29

🚨 Excited to announce my brand-new, all-in-one ICH calculator page! It brings together multiple intracerebral hemorrhage stroke calculators in one comprehensive spot for assessments + decisions. 🧠🩸

Explore, use, share, and REMIX!💿📼
Check it out here: tinyurl.com/ICHcalc

ICH Calculator One Stop Shop

tinyurl.com

1 2

Reposted by Micah Etter, MD

CORE IM @coreimpodcast.bsky.social · May 29

#ThrowbackThursday to our episode on DAPT 🩸

Did you know that ticagrelor inhibits adenosine reuptake, which can cause bradycardia and dyspnea, sometimes resulting in patient self-discontinuation ‼️

www.coreimpodcast.com/2021/04/07/5...

2 3

Reposted by Micah Etter, MD

Ali Christy, MD, PhD @oligoclonalband.medsky.social · May 26

For reasons, I was reading the 1902 memorial of early American neurologist J.T. Eskridge this morning - and Frank Norbury has some delightful thoughts on enthusiasm that I thought I'd share 1/5

The Journal of the American Medical Association, Vol XXXIX, Chicago, Illinois, November 8, 1902

Addresses.
Memorial to the late J.T. Eskridge, M.D., of Denver, Colo.
Chairman of the Section on Neurology of the American Medical Association.
Charles K. Mills, M.D.
Philadelphia
and
Frank P. Norbury, M.D.
Jacksonville, Ill.

1 1 4

Reposted by Micah Etter, MD

NEJM.org @nejm.org · May 26

In the TAK-861-2001 trial involving 112 participants with narcolepsy type 1, oveporexton significantly improved measures of wakefulness, sleepiness, and cataplexy over a period of 8 weeks. Full trial results and Research Summary: nej.md/3ZdlKNi 

#MedSky #NeuroSky

The New England Journal of Medicine

Oveporexton for Narcolepsy Type 1
A Research Summary based on Dauvilliers Y et al. | 10.1056/NEJMoa2405847 | Published on May 15, 2025

Visual representations of the patients in the trial and the treatments they were assigned.

Read the full Research Summary at NEJM.org.

1 4

Reposted by Micah Etter, MD

josh farkas 💊 @pulmcrit.bsky.social · May 16

A recent article seems to imply that we don't need to check an ECG before giving ondansetron.

This is largely correct, but I disagree with some of their points.

I wrote a letter to the editor that I posted in the blog, so you can access it easily here: emcrit.org/pulmcrit/twd... #EMIMCC

2 3 16

Reposted by Micah Etter, MD

NEJM.org @nejm.org · May 15

In a new editorial, Andrea L. Gropman, MD, and Alexis C. Komor, PhD, describe the foundations of an N-of-1 gene-editing study to treat an infant with a urea-cycle disorder. Read the editorial: nej.md/430hLWR

#ASGCT2025 @asgct.bsky.social #ScienceSky

Personalized Gene Editing to Treat an Inborn Error of Metabolism | NEJM

In this editorial, the authors describe the foundations of an N-of-1 gene-editing study to treat an infant with a urea-cycle disorder.

nej.md

1 8 16

Reposted by Micah Etter, MD

Richard Choi, DO, FNCS @rkchoi.bsky.social · May 14

1/ Hi 👋 #medtwitter #neurotwitter #neurocritcare #FOAMed #meded have an impressive image to show you in the form of another case, albeit, this one with a sad ending

1 3 9