Matt Sikora
@mjsikora.bsky.social
Assoc Prof at CU Anschutz, Cancer biologist, focus on #lobular breast cancer and gyn cancers, estrogen receptor pharmacology, and basic mechs in cancer disparities. Posts are my own. He/Him.
www.sikoralab.com
www.sikoralab.com
Pinned
Matt Sikora
@mjsikora.bsky.social
· Nov 25
Home
welcome to the sikora lab
www.sikoralab.com
Hey #oncosky and 🧪 friends - so glad you're here!
A quick (re)intro to the Sikora Lab (www.sikoralab.com):
We study:
1) #lobular breast cancer and its complicated relationship w estrogen.
2) gyn / ovarian cancer, metabolic parallels w #lobular, and genetic links to health disparities.
1/n
A quick (re)intro to the Sikora Lab (www.sikoralab.com):
We study:
1) #lobular breast cancer and its complicated relationship w estrogen.
2) gyn / ovarian cancer, metabolic parallels w #lobular, and genetic links to health disparities.
1/n
Reposted by Matt Sikora
As someone who's spent a quarter century in Academia, I can't abide the "why bother with college when you have AI and YouTube" nonsense because THIS, this right here, is one of the most important reasons for going to college.
Thinking a lot lately about the simple fact that college allows people to spend about 15 weeks immersed in a disciplinary conversation with an expert in that field. And what a special thing that is.
November 21, 2025 at 3:21 PM
As someone who's spent a quarter century in Academia, I can't abide the "why bother with college when you have AI and YouTube" nonsense because THIS, this right here, is one of the most important reasons for going to college.
Reposted by Matt Sikora
Braver than like 90% of reporters for no reason at all.
this is the correct way to react to anything the president says-
November 20, 2025 at 9:59 PM
Braver than like 90% of reporters for no reason at all.
Reposted by Matt Sikora
The President of the United States just called for Democratic members of Congress to be executed. "HANG THEM", he posted.
If you're a person of influence in this country and you haven't picked a side, maybe now would be the time to pick a fucking side.
If you're a person of influence in this country and you haven't picked a side, maybe now would be the time to pick a fucking side.
November 20, 2025 at 4:15 PM
The President of the United States just called for Democratic members of Congress to be executed. "HANG THEM", he posted.
If you're a person of influence in this country and you haven't picked a side, maybe now would be the time to pick a fucking side.
If you're a person of influence in this country and you haven't picked a side, maybe now would be the time to pick a fucking side.
Reposted by Matt Sikora
Reposted by Matt Sikora
Defunding scientists for the nationality of who they co-author with or who they train.
One of the most radical attack on freedom of speech in US history. A far right nationalist destruction of US science. Such a shameful time to be an American that this racist stupidity has become mainstream.
One of the most radical attack on freedom of speech in US history. A far right nationalist destruction of US science. Such a shameful time to be an American that this racist stupidity has become mainstream.
“The prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.”
U.S. Congress considers sweeping ban on Chinese collaborations
Researchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students
www.science.org
November 14, 2025 at 3:32 AM
Defunding scientists for the nationality of who they co-author with or who they train.
One of the most radical attack on freedom of speech in US history. A far right nationalist destruction of US science. Such a shameful time to be an American that this racist stupidity has become mainstream.
One of the most radical attack on freedom of speech in US history. A far right nationalist destruction of US science. Such a shameful time to be an American that this racist stupidity has become mainstream.
November 14, 2025 at 5:20 PM
Reposted by Matt Sikora
After shutdown guidance:
As of today, we can confirm that we will be rescheduling all October and November grant application submission deadlines (specific dates to be announced in a future Notice).
As of today, we can confirm that we will be rescheduling all October and November grant application submission deadlines (specific dates to be announced in a future Notice).
November 14, 2025 at 4:55 PM
After shutdown guidance:
As of today, we can confirm that we will be rescheduling all October and November grant application submission deadlines (specific dates to be announced in a future Notice).
As of today, we can confirm that we will be rescheduling all October and November grant application submission deadlines (specific dates to be announced in a future Notice).
Reposted by Matt Sikora
While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.
November 13, 2025 at 1:25 PM
While the government was shut down, 379 NIH study section meetings (containing 24,380 grant applications) were postponed. NIH is committed to getting these reviewed, but please be patient and understanding with staff, as this is a complex and heavy lift.
This on top of having the October submissions to process, and recruit/assign reviewers. Hard to imagine how CSR just picks up where they left off with the depletions and chaos.
Up to 323 cancelled CSR study sections. That's more than the 204 sections cancelled earlier this year. Rescheduling is going to be a hot mess with NIH staff reductions and study section members heading into finals and holidays that limit availability. 🧪
Been a rough year for federally funded scientists, and I hate to add another tab to this spreadsheet. So far, the shutdown has resulted in cancellation of 161 CSR study sections. 🧪https://docs.google.com/spreadsheets/d/1lLEx14q7HKrlYahQYJaN6aHKpMqSMJwX4aenyL5g_ZU/edit?usp=sharing
November 11, 2025 at 10:01 PM
This on top of having the October submissions to process, and recruit/assign reviewers. Hard to imagine how CSR just picks up where they left off with the depletions and chaos.
Reposted by Matt Sikora
Save the date: our faculty job market series continues this Wed, Nov12 at 3pm ET / 12p PT!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
November 10, 2025 at 7:28 PM
Save the date: our faculty job market series continues this Wed, Nov12 at 3pm ET / 12p PT!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
Topic: on-site interviews + seminars
Come hear our junior faculty share our thoughts/advice! There will also be time for Q&A.
Registration link in flyer - see you soon!
Reposted by Matt Sikora
Reposted by Matt Sikora
Are you a #Colorado resident who buys health insurance on the state marketplace (Connect for Health Colorado) & have seen a spike in your premiums for next year? DM me if you're willing to talk about the bill. Thanks! #copolitics
November 6, 2025 at 3:38 PM
Are you a #Colorado resident who buys health insurance on the state marketplace (Connect for Health Colorado) & have seen a spike in your premiums for next year? DM me if you're willing to talk about the bill. Thanks! #copolitics
Reposted by Matt Sikora
Reposted by Matt Sikora
Beshear: Let me be clear. The president has both the funding and the authority to fund snap during a shutdown. In fact, every other president in every other shutdown has done so. People going hungry in this instance is a choice that this president has made.
November 5, 2025 at 4:44 PM
Beshear: Let me be clear. The president has both the funding and the authority to fund snap during a shutdown. In fact, every other president in every other shutdown has done so. People going hungry in this instance is a choice that this president has made.
For Halloween, the Sikora Lab is excited to announce the release of the debut self-titled album from **MITOTIC CATASTROPHE** with chart topping hits:
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
October 30, 2025 at 8:28 PM
For Halloween, the Sikora Lab is excited to announce the release of the debut self-titled album from **MITOTIC CATASTROPHE** with chart topping hits:
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
- Pour Some Agar on Me
- You Give Science a Bad Name
- Sweet Graph 'o Mine
- We're Not Gonna Fake it
- Welcome to the Data
- Back in Lab
Rock on!!!
Reposted by Matt Sikora
Endocrine research conference: Dr Maggie Musick from the Sikora lab @mjsikora.bsky.social discussed mechanisms of tumorigenesis in lobular breast cancer.
#cancer #CUPathology
#cancer #CUPathology
October 22, 2025 at 6:01 PM
Endocrine research conference: Dr Maggie Musick from the Sikora lab @mjsikora.bsky.social discussed mechanisms of tumorigenesis in lobular breast cancer.
#cancer #CUPathology
#cancer #CUPathology
I know & trust that NIH staff will get this round of reviews done. Yet having done my own CSR reviews 'for nothing' & with my own R01 sitting unreviewed now, working on another NIH grant has never felt so painful and futile. A quiet impact on science, perhaps, robbing the joy from looking ahead.
If you are serving on NIH study sections that have been cancelled, PLEASE continue to work on your reviews. NIH will do everything their power to ensure the meetings happen eventually, and the more prepared you are when those meetings are rescheduled, the better.
Welp. Thanks to the Republican gov shutdown I have a bunch of hours back in my week due to a NIH study section not meeting.
These poor applicants. They will be waiting week by week for government to reopen and to find out what will happen to their grant application.
These poor applicants. They will be waiting week by week for government to reopen and to find out what will happen to their grant application.
October 20, 2025 at 3:52 PM
I know & trust that NIH staff will get this round of reviews done. Yet having done my own CSR reviews 'for nothing' & with my own R01 sitting unreviewed now, working on another NIH grant has never felt so painful and futile. A quiet impact on science, perhaps, robbing the joy from looking ahead.
Reposted by Matt Sikora
. @cucancercenter.bsky.social member @mjsikora.bsky.social, PhD, is a leader in research into lobular breast cancer, an understudied cancer type that’s on the rise in American women and has sharply lower survival rates several years after diagnosis than more common breast cancers. #cucityofhealth
An Understudied Type of Breast Cancer Poses a Lurking Threat
Matt Sikora, PhD, seeks better answers for lobular breast cancer, which can be harder to detect & has lower survival rates after several years than other types.
news.cuanschutz.edu
October 13, 2025 at 7:11 PM
. @cucancercenter.bsky.social member @mjsikora.bsky.social, PhD, is a leader in research into lobular breast cancer, an understudied cancer type that’s on the rise in American women and has sharply lower survival rates several years after diagnosis than more common breast cancers. #cucityofhealth
Reposted by Matt Sikora
After Trump got his Covid shot, he chose to fire the scientists protecting the rest of us from diseases.
October 11, 2025 at 4:05 PM
After Trump got his Covid shot, he chose to fire the scientists protecting the rest of us from diseases.
Reposted by Matt Sikora
THAT’S NOT HOW IT WORKS
RFK Jr on Tylenol and autism: "It is not proof. We're doing the studies to make the proof."
October 9, 2025 at 5:11 PM
THAT’S NOT HOW IT WORKS
Reposted by Matt Sikora
Reposted by Matt Sikora
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
sites.stat.columbia.edu
October 4, 2025 at 5:35 PM
Sometimes I think about how from 1935-1975ish, Bell Labs produced an insane amount of revolutionary science and technology, including 11 Nobel Prizes, the transistor, UNIX, C, the laser, the solar cell, information theory, etc. The secret? Provide scientists with ample, steady, no-strings funding.
Reposted by Matt Sikora
I am just so fucking proud of her.
October 3, 2025 at 7:45 PM
I am just so fucking proud of her.
Reposted by Matt Sikora
NEWS: The F.D.A. approved a new generic version of the abortion pill mifepristone. www.nytimes.com/2025/10/02/h...
F.D.A. Approves Generic Abortion Pill as Opponents Push Trump for New Restrictions
www.nytimes.com
October 2, 2025 at 11:06 PM
NEWS: The F.D.A. approved a new generic version of the abortion pill mifepristone. www.nytimes.com/2025/10/02/h...
Reposted by Matt Sikora
Donald Trump is conditioning federal funding to universities on the signing of a loyalty pledge to his agenda.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
Trump Administration Asks Colleges to Sign ‘Compact’ to Get Funding Preference
Demands sent to nine top schools included pledging to freeze tuition for five years and to commit to strict definitions of gender.
www.nytimes.com
October 2, 2025 at 8:11 PM
Donald Trump is conditioning federal funding to universities on the signing of a loyalty pledge to his agenda.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.
This reeks of authoritarianism, and the universities should reject this hostage-taking of their funding.