Lightnews — Scholar-powered news

Tim Feinstein @timnfeinstein.bsky.social · 2h

Seeing it cytokinesis proceed to separation, live, is the ultimate test of a scope system! Even after I pass every other check for phototoxicity, cells still collapse at that stage to bi-nucleate if I use any more than the bare minimum of photons.

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Reposted by Tim Feinstein

Manuel Thery @manuelthery.bsky.social · 4h

We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...

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Tim Feinstein @timnfeinstein.bsky.social · 9h

Exciting work! I can’t help being curious what the Golgi looks like with the different BRAF mutants present.

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Tim Feinstein @timnfeinstein.bsky.social · 1d

The avalanche was on

Marjorie James Keenan @unenthusiast.com · 2d

In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

rm -rf ~/

hammancheez @hammancheez.bsky.social · 2d

"The chancellor approved it"

Tim Feinstein @timnfeinstein.bsky.social · 1d

7 was too derivative and weirdly self aware about it, 8 zagged in really jarring way and basically looked right at the camera and begged Abrams to break out of his rut serving re-warmed leftovers. 9 said NO with the kind of vehemence you normally expect from someone throwing a chair.

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Tim Feinstein @timnfeinstein.bsky.social · 2d

You are now acquainted with the food hate click industry

Tim Feinstein @timnfeinstein.bsky.social · 3d

Do you think there’s any chance the subset of psychosis pts who do show visible abnormalities also have a higher rate of heart issues? That would be consistent with the last project(s) that I worked on in academia.

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Reposted by Tim Feinstein

Anne Carpenter @drannecarpenter.bsky.social · 4d

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

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Tim Feinstein @timnfeinstein.bsky.social · 3d

It’s like opening a Caribou on a block that already has three Starbucks

Tim Feinstein @timnfeinstein.bsky.social · 4d

The unique pleasure of loading a 24-place centrifuge

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Tim Feinstein @timnfeinstein.bsky.social · 4d

2025. Jesus christ.

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Tim Feinstein @timnfeinstein.bsky.social · 5d

Wicked cool. Congrats on great looking results right out of the box.

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Tim Feinstein @timnfeinstein.bsky.social · 5d

That’s a soccer ball! Did you expect pentagon-hexagon facets?

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Tim Feinstein @timnfeinstein.bsky.social · 6d

I love how evocative your raven is!

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Tim Feinstein @timnfeinstein.bsky.social · 7d

For how much birria stew my family has eaten in the last few days, I still have a shocking amount of birria stew.

12yo takes it in tacos. I try to argue that cuts down on the total birria she can remove in a sitting, but resistance is strong.

An intimidating amount of birria stew in a large red pot

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Tim Feinstein @timnfeinstein.bsky.social · 7d

As Roman leaders knew well, the best way to ensure the loyalty of forces you command is to not pay them.

More Perfect Union @moreperfectunion.bsky.social · 7d

A new White House memo says that furloughed federal workers aren't entitled to back pay.

This is clearly against the law, which guarantees furloughed federal employees back pay for the duration of a government shutdown.

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Tim Feinstein @timnfeinstein.bsky.social · 8d

Clarke’s book Against All Enemies is one of the better ones to come out of the GWB years. It tells the story of What Happened about as well as anyone can.

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Tim Feinstein @timnfeinstein.bsky.social · 8d

Richard Clarke. Reassigned I think. Al Gore organized the commission to figure out the bin Laden situation after a Twin Towers car bomb in 1998. Bushies deep sixed the whole thing to focus 100% 24/7 in on Iraq.

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Tim Feinstein @timnfeinstein.bsky.social · 9d

Ten is experiencing what genX felt when late millennials warmed up to the Star Wars prequels

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Tim Feinstein @timnfeinstein.bsky.social · 9d

Have to admit that I really suffered when my FE2 finally gave up in 2005 and I had to go digital. I wasn’t very good with it but I carried my Galen Rowell books everywhere and felt like I was doing something cool and serious, rather than just getting up early and hiking about.

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Tim Feinstein @timnfeinstein.bsky.social · 9d

Fair! I’m from the school of thought that making a bad thing a lot harder has some value, though you still have to consider ROE. Film cassette Westerns are a big PITA and I wouldn’t wish them on people casually.

Tim Feinstein @timnfeinstein.bsky.social · 9d

If it does, here’s a tip from an old bench critter: stack the cassette with three unexposed films. That way you have a lot of dynamic range between the top film and the bottom one, in case you need to capture the bright and dim bands.

Curious to know what @elisabethbik.bsky.social thinks of that.

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Tim Feinstein @timnfeinstein.bsky.social · 9d

Listening to this discussion touch on film negatives and authenticity…it hit me that Westerns blots have always been ground zero for fake images, and AI really democratizes access to that.

I wonder whether a film cassette could return as the gold standard when auditability&integrity are paramount.

tombobwarland @tombobwarland.bsky.social · 11d

There’s a new photography podcast! It’s a bit chaotic 😂. open.spotify.com/show/5vPZToh...

Episode 0 - And so it begins...

open.spotify.com

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Tim Feinstein @timnfeinstein.bsky.social · 10d

You can’t make a tomlet without breaking a few Portlands

Tim Feinstein @timnfeinstein.bsky.social · 10d

Can’t wait to check it out!

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