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Denis Chrétien @dchretien.bsky.social · 11d

Sauf qu'en Bretagne, elle a rendez-vous avec les nuages 😜 On désespère pas que tu viennes nous faire une conférence à l'Institut de Génétique et Développement de Rennes un de ces quatre 😉

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Denis Chrétien @dchretien.bsky.social · 12d

Trip to the center of the microtubule 😵‍💫
#microtubule

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clairesnaylor.bsky.social @clairesnaylor.bsky.social · 13d

🚨 Webinar Alert! - Revolutionizing Structural Biology
On Oct 1 Dr. Nick Ariotti (U. Queensland) will share how his team imaged microtubules in lysate at 7.1 Å with a cryoTEM and NO traditional purification steps.

Register here: ter.li/66bytl

#structuralbiology #proteinmicroscopy #cryoEM #cryoET

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Denis Chrétien @dchretien.bsky.social · 23d

Microtubules: from atoms to complex systems www.embl.org/about/info/c...

Microtubules: from atoms to complex systems

www.embl.org

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BioCytoLab @schaedellab.bsky.social · 27d

Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳

We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.

Congratulations @subhambiswas.bsky.social!

www.nature.com/articles/s41...

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Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 28d

Story on our Asgard microtubule paper by Nikki Greenwood: www.quantamagazine.org/tiny-tubes-r...
Thanks to all interviewees🎤

Tiny Tubes Reveal Clues to the Evolution of Complex Life | Quanta Magazine

Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.

www.quantamagazine.org

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Institut Jacques Monod @ijmonod.bsky.social · 28d

📣 Paris Cytoskeleton day 2025 - Registrations are open!

📆 November 14th
📍 Institut Jacques Monod

🔗 pcd2025.sciencesconf.org
Abstract submission closes on 19 October
Registration closes on 7 November

@romet-jegou-lab.bsky.social @upcite.bsky.social @cnrs-idf-villejuif.bsky.social

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Gautam Dey @gautamdey.bsky.social · Aug 7

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social

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MRC Laboratory of Molecular Biology @mrclmb.bsky.social · Aug 4

The LMB recently hosted a symposium to mark 50 years since Richard Henderson and Nigel Unwin published the structure of bacteriorhodopsin, the first 3D structure of a protein determined by #cryoEM.

Read about the event and find more photos here: www2.mrc-lmb.cam.ac.uk/the-structur...

#LMBNews 🧪🔬

Attendees of the recent bacteriorhopsin symposium, photographed from above.

Black and white photograph of Nigel Unwin and Richard Henderson sitting outside the LMB, 1991

Symposium attendees applauding in the LMB's Max Perutz Lecture Theatre.

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Kat Toropova @kattoropova.bsky.social · Jul 29

Thrilled to see our study on how kinesin-2 motors are switched on and off published in @natsmb.nature.com ⚛️

➡️ www.nature.com/articles/s41...

Congrats to all authors from me and Anthony 🎉 @dunnschool.bsky.social Check out this animation made by talented PhD student @matthew-batisio.bsky.social 😆

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Josh Dickerson @joshdcryoem.bsky.social · Jun 28

Check out our recent review discussing the merits of tilt series vs single micrographs for in situ cryo-EM! www.sciencedirect.com/science/arti...

To tilt or not to tilt? Strategies for in situ cryo-EM data collection

Recent breakthroughs in single-particle cryogenic electron microscopy (cryo-EM) and protein structure prediction have transformed our ability to resol…

www.sciencedirect.com

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Reposted by Denis Chrétien

Florian Wollweber @florianwollweber.bsky.social · Jun 27

After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber
We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis
First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6

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Reposted by Denis Chrétien

Bettina Böttcher @boettchercryoem.bsky.social · Jun 25

Our paper on Lymphostatin is now out (rdcu.be/etk2v). It shows #cryoEM structures of this huge virulence factor revealing amazing domain reorganisations.
Very enjoyable collaborating with the Stevens Lab in Edinburgh and the Boersch Lab in Jena to see how it gets into cells.
@uni-wuerzburg.de 🧪❄️

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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · Jun 19

🚨 New preprint!
Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM
www.biorxiv.org/content/10.1...

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A/Prof Sam Stehbens PhD (She/Her) @samstehbens.bsky.social · Nov 9

it never gets old...... #microtubule dynamics - the fireworks of EB comets #microscopy

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Denis Chrétien @dchretien.bsky.social · Jun 12

Beautiful 😍

Oli Clarke @olibclarke.bsky.social · Jun 12

1/x New story - the structure of the Vault cap, at 2.3Å! Matching a beautiful preprint from @sjorsscheres.bsky.social, we show that the cap of the vault particle has C13 symmetry, in contrast to the 39-fold symmetry of the body. Study lead by talented postdoc @huanli00.bsky.social from my group! ⬇️

At left, a reconstruction of the vault cap with C39 symmetry imposed; at right, the reconstruction after identifying the correct symmetry, with the three non-equivalent protomers highlighted.

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Denis Chrétien @dchretien.bsky.social · Jun 2

Dual-axis cryo-ET on cryo-FIB milled lamella 🙂 www.researchsquare.com/article/rs-6...
#CryoEM

On-lamella dual-axis cryo-electron tomography and modelling of lamella stability

Cryogenic electron tomography (cryo-ET) of cryogenic focused ion beam (cryo-FIB) milled lamellae enables the study of 3D cellular architecture in near-native conditions at nanometer-scale resolution. ...

www.researchsquare.com

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European Research Council (ERC) @erc.europa.eu · May 28

🎉 Congratulations to Wolfgang Baumeister @maxplanck.de, awarded the 2025 #ShawPrize in Life Science & Medicine for pioneering work in cryo-ET!

Learn more 👉 europa.eu/!JBXDBG
#FrontierResearch #ERCSyG #CryoET #StructuralBiology #shawprize2025

ERC grantee wins the Shaw Prize in Life Science and Medicine

2025 Shaw Prize honours ERC-funded research in molecular imaging

europa.eu

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Institut Pasteur | 130 years of biomedical research @pasteur.fr · May 26

Zoom into a human cell infected by Shigella, the bacteria behind dysentery. Using cryo-EM, @leaswistak.bsky.social and team revealed how it pierces cells with molecular syringes. Stunning science at the nanoscale.

@enningalab.bsky.social @jytinevez.bsky.social @nanoimaging.bsky.social

#CryoEM

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Denis Chrétien @dchretien.bsky.social · May 20

Coupes tissulaires d'un tissus visualisé en 3D par microscopie électronique ? Mais quel tissus ... Au niveau du coeur ? (aorte en haut à gauche ?).

Denis Chrétien @dchretien.bsky.social · May 15

N'est-ce pas deux galaxies en interaction ?

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Philippe Van der Stappen @phaips.vd.st · May 6

Hey #TeamTomo,
Ever been in need of a tutorial about the fundamentals of cryo-electron tomography? From preprocessing raw frames to high-res subtomogram averaging?
That's why @florentwaltz.bsky.social and I made this website!

tomoguide.github.io

Follow the thread 1 /🧵
#CryoET #CryoEM 🔬🧪

Welcome to TomoGuide

A step-by-step Cryo-ET guide

tomoguide.github.io

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Marine Biological Laboratory @mblscience.bsky.social · May 5

It's #MicroscopyMonday, so let's take a peek into the 🔬
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.

Dr. Inuoe premiered his research at MBL.

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Reposted by Denis Chrétien

Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · May 6

Choose Europe (France) for Science #ESR

(credit : Jérôme Sié)

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Denis Chrétien @dchretien.bsky.social · May 1

I'm surprised that Didier Raoult is not in the author list 😂

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