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Reposted by Elisabetta Cacace

Craig MacLean @craigmaclean.bsky.social · 13d

New ERC funded computational postdoc position in my lab! We are looking for someone who will study the genomics of bacterial evolution using samples from experimental evolution and clinical trials. Lots of opportunities for interesting and fun collaboration!
my.corehr.com/pls/uoxrecru...

Job Details

my.corehr.com

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Reposted by Elisabetta Cacace

Emma Slack @mucosalimmunology.bsky.social · 28d

Come and be my colleague at the Dunn School! It‘s a brilliant place to work and exciting to be building up our immunology team. Do apply. Do pass on the news 💉🧬🦠🔬🧫

The Dunn School, Oxford @dunnschool.bsky.social · 28d

We're hiring (again)!

We are looking for an associate professor in cell and molecular biology, with a particular focus on immunology (defined broadly)

If you have a great record and exciting plans, consider joining our thriving and welcoming department

www.path.ox.ac.uk/vacancy/asso...

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Reposted by Elisabetta Cacace

Ina Huppertz @inahuppertz.bsky.social · Aug 24

🎉 We’re excited to share our very first preprint!! 🎉
"Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells"
👉 doi.org/10.1101/2025...

#FirstPreprint #StemCells #Metabolism #Epigenetics #AcetylCoA #HBP #Pluripotency #NewScience

Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells

Pluripotent stem cells (SCs) rely on metabolic rewiring to regulate self-renewal and differentiation. The hexosamine biosynthetic pathway (HBP) integrates multiple metabolic inputs to produce uridine ...

doi.org

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Elisabetta Cacace @elisca.bsky.social · Aug 15

How diverse are E. coli capsules? How are they linked to ecology and disease? Find out with > 25,000 genomes and MAGs including undersampled environments and hosts from all over the world.
Great genomics - glycobiology synergy in Sunagawa and Slack groups at ETH!
www.biorxiv.org/content/10.1...
🧪🧫🔬

The natural diversity of E. coli transporter-dependent capsules

Serotyping of bacteria using genomic information ( in silico serotyping) has increasingly replaced serology. However, the E. coli capsule serotyping system has been largely abandoned since the 1990s, ...

www.biorxiv.org

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Reposted by Elisabetta Cacace

Michael Kuhn @biocs.bsky.social · Aug 15

We're very happy to release our new database Metalog metalog.embl.de ! It offers manually curated and harmonised contextual data for 110k metagenomics samples across the globe, incl. precomputed taxonomic profiles, for interactive browsing and for download 🧵 1/7

#microsky

Metalog

Metalog is a repository of manually annotated metadata (or contextual data) for metagenomic sequencing data from across the globe.

metalog.embl.de

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Reposted by Elisabetta Cacace

Quinn Sievers @quinnsievers.bsky.social · Jul 6

As a first-year oncology fellow at Memorial Sloan Kettering in New York City I had the privilege of rotating through all of the clinics. Lung, beast, ovarian, leukemia, lymphoma. 1/7

Eric Topol @erictopol.bsky.social · Jul 6

Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...

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Reposted by Elisabetta Cacace

Tami Lieberman @contaminatedsci.bsky.social · Jun 30

Our paper demonstrating that within-species warfare interactions are ecologically important on human skin is now published in Nature Micro! www.nature.com/articles/s41...

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Reposted by Elisabetta Cacace

Sebastian Schmidt @tsbschm.bsky.social · Jun 27

The team's first preprint is out!

Led by ‪
‪@vishnuprasoodanan.bsky.social‬‬ & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data?

A 🧵.

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · Jun 27

A census of hidden and discoverable microbial diversity beyond genome-centric approaches https://www.biorxiv.org/content/10.1101/2025.06.26.661807v1

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Elisabetta Cacace @elisca.bsky.social · Jun 24

Looking forward to #EESMicrobiology and excited to present our latest work on E. coli capsules on Friday! www.embl.org/about/info/c...

New approaches and concepts in microbiology

www.embl.org

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Elisabetta Cacace @elisca.bsky.social · Jun 21

Check out this framework for de novo protein design by @mjendrusch.bsky.social and Kashif Sadiq! Happy we could contribute with our favourite phage defence system.

Michael Jendrusch @mjendrusch.bsky.social · Jun 19

Happy to announce the first paper from my PhD at Korbel group at @embl.org has finally been published:
embopress.org/doi/full/10.1038…
Collaborating with @typaslab.bsky.social, @hennig-lab.bsky.social and the EMBL PEPCF, we designed de novo inhibitors to a bacterial phage defense system 1/🧵

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Reposted by Elisabetta Cacace

Gregor Rot 🌈 @grexor.bsky.social · May 10

Habemus pubScan! 🎉

Introducing pubScan, a new way to explore your PubMed publications through the lens of co-authorship.

🔍 Check it out at: pubscan.expressrna.org

❤️ Love it? Show your support by liking, sharing, and spreading the word.

#pubscan

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Reposted by Elisabetta Cacace

Marjon de Vos @lizscurious.bsky.social · May 8

When things add up: environmental structure and microbial interactions drive antibiotic-resistance plasmid evolution.

New paper from the lab, and the third chapter of Lars Zandbergen’s thesis!

www.biorxiv.org/cgi/content/...

When things add up: environmental structure and microbial interactions drive antibiotic-resistance plasmid evolution

Antimicrobial resistance is recognized as a major global health threat. Pathogens can rapidly evolve resistance which diminishes the impact of antimicrobial treatments. The presence of other microbes ...

www.biorxiv.org

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Elisabetta Cacace @elisca.bsky.social · May 5

Our paper has been selected among Editors' Highlights for Microbiology! @natcomms.nature.com www.nature.com/collections/... 🧪🔬🧫

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Reposted by Elisabetta Cacace

Lisa Maier Lab | Tübingen @lisamaierlab.bsky.social · Apr 30

Here are our ideas on developing tools and technologies for anaerobic bacteria! We hope you enjoy the read as much as we enjoyed brainstorming on the topic...

Thomas Clavel @tclavel.bsky.social · Apr 29

Here we share thoughts on next-gen cultivation: rdcu.be/ejPSb. Hope it helps 😄 Was fun to write with great colleagues @lisamaierlab.bsky.social @jselkrig.bsky.social @baerboletta.bsky.social @typaslab.bsky.social @mmmicrobiomelab.bsky.social @leibniz-dsmz.bsky.social @westermannlab.bsky.social

Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research

Nature Biotechnology - Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.

rdcu.be

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Elisabetta Cacace @elisca.bsky.social · Apr 24

Thanks Annique!

Elisabetta Cacace @elisca.bsky.social · Apr 24

Viable link: www.nature.com/articles/s41...

Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria - Nature Communications

Nitroxoline is a bacteriostatic quinoline antibiotic, known to form complexes with metals, with few clinical applications. Here, Cacace et al. show that the compound displays a broad activity spectrum...

www.nature.com

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Elisabetta Cacace @elisca.bsky.social · Apr 24

Do we really know the antibiotics that we already have?

Check out our story on 60y old drug nitroxoline and its new tricks!
@goetheuni.bsky.social @embl.org
www.nature.com/articles/s41...

+ great piece from the synchrotron @esrf.fr where we chased nx effects on metals
www.esrf.fr/home/news/ge...

www.nature.com

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The Dunn School, Oxford @dunnschool.bsky.social · Apr 4

New study by @mucosalimmunology.bsky.social (Dunn School and @ethzurich.bsky.social) with Médéric Diard (@biozentrum.unibas.ch) reveals how combining vaccines with friendly bacteria can boost vaccination efficacy and potentially reduce reliance on antibiotics

www.path.ox.ac.uk/news-article...

Boosting vaccines with harmless bacteria to fight intestinal pathogens - Dunn School

Published in Science, a ground-breaking study by the Slack group reveals how combining vaccines with friendly bacteria can boost vaccination efficacy and potentially reduce reliance on antibiotics.

www.path.ox.ac.uk

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Annika Hausmann @hausmannannika.bsky.social · Mar 23

I am very excited to share our latest publication on the effect of systemic #endotoxin on intestinal #microbiota spearheaded by the brilliant Sanne Kroon at the Hardt lab @eth-dbiol.bsky.social @ethzurich.bsky.social @naturecomms.bsky.social

👉🏼 rdcu.be/eelLn

Sublethal systemic LPS in mice enables gut-luminal pathogens to bloom through oxygen species-mediated microbiota inhibition

Nature Communications - Acute systemic immune activation may affect gut-luminal colonisation dynamics. Here, the authors show that LPS exposure in mice elevates gut-luminal oxygen species levels,...

rdcu.be

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Shraddha Shitut @shetoot.bsky.social · Mar 4

Excited to share our paper published in @currentbiology.bsky.social that explores the consequences of having multiple genomes in a bacterial model system and it’s benefits in a multidrug environment ! www.cell.com/current-biol...

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Elisabetta Cacace @elisca.bsky.social · Mar 5

Super cool Shraddha!!

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Reposted by Elisabetta Cacace

Brochado Lab @brochadolab.bsky.social · Feb 20

Brochado and Maier labs in Germany are looking for a PhD student to study horizontal gene transfer in bacteria. ENDAMR Marie Curie doctoral network (endamr.eu) - an amazing opportunity to work with top scientists in the field all around Europe!
www.cmfi.uni-tuebingen.de/mariecuriephd

endamr.eu

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Reposted by Elisabetta Cacace

Emma Slack @mucosalimmunology.bsky.social · Jan 26

Interested in microbial #metabolism, #mucosalbiology and #UTI? Then check out the open postdoctoral position in the Mucosal Immunology Group at ETH Zurich! NB: All applications must go via the ETH job portal:

www.jobs.ethz.ch/job/view/JOP...

Closing date: 24th Feburary
🧪🧫🔬

Postdoctoral researcher –Understanding bacterial metabolism in the urinary tract

www.jobs.ethz.ch

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STCmicrobeblog @stcmicrobeblog.bsky.social · Jan 24

"The world has been through anti-science cycles before"

not microbiology related, but a 🧵 worth reading

a grassland chase 🌾🌾🌾🌾 @chasesolidago.bsky.social · Jan 23

The world has been through anti-science cycles before, to disastrous results

On a detour on my lit review, a mosey through the history of our familiar friend, the standard onion (Allium cepa) brought me right to one of botany's greatest cautionary tales of what happens when ideology overrides data

a illustration of our standard kitchen onion, Allium cepa, from 1586. Handcolored engraving

a black and white photograph of a white man in a suit, holding stalks of some plant, possibly corn or some sort of grain. Photo depicts Nikolai Vavilov (1887 - 1943)

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Reposted by Elisabetta Cacace

Typas Lab @typaslab.bsky.social · Dec 16

You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...

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