Merve Tepe, PhD
@mervetepephds.bsky.social
PhD MICROBIOLOGIST /
Phage Therapy, AMR, Biofilms, Drug Design and some other topics
@remissionbiome.bsky.social &
@renegaderesearch.bsky.social team
DEFEND SCIENCE, RESIST IGNORANCE
Ankara/Boston
Phage Therapy, AMR, Biofilms, Drug Design and some other topics
@remissionbiome.bsky.social &
@renegaderesearch.bsky.social team
DEFEND SCIENCE, RESIST IGNORANCE
Ankara/Boston
Pinned
"Behold the turtle 🐢 He makes progress only when he sticks his neck out. " J. Conant
Reposted by Merve Tepe, PhD
GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.
December 9, 2025 at 5:00 PM
GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.
Reposted by Merve Tepe, PhD
My latest for @thenation.com: "Public Health Needs a New Motto: No Apologies, No Surrender"
It’s time we stopped flinching at the assaults of the far right—and started fighting back.
www.thenation.com/article/soci...
It’s time we stopped flinching at the assaults of the far right—and started fighting back.
www.thenation.com/article/soci...
Public Health Needs a New Motto: No Apologies, No Surrender
It's time we stopped flinching at the assaults of the far right—and started fighting back.
www.thenation.com
December 9, 2025 at 10:27 AM
My latest for @thenation.com: "Public Health Needs a New Motto: No Apologies, No Surrender"
It’s time we stopped flinching at the assaults of the far right—and started fighting back.
www.thenation.com/article/soci...
It’s time we stopped flinching at the assaults of the far right—and started fighting back.
www.thenation.com/article/soci...
Reposted by Merve Tepe, PhD
I'm an Infectious Diseases Doctor. Our Pipeline of Experts Is in Distress.
Had the opportunity to share my reflections on the challenges the ID specialty is facing on.
@medpagetoday.com
#IDSky
www.medpagetoday.com/opinion/seco...
Had the opportunity to share my reflections on the challenges the ID specialty is facing on.
@medpagetoday.com
#IDSky
www.medpagetoday.com/opinion/seco...
Opinion | I'm an Infectious Diseases Doctor. Our Pipeline of Experts Is in Distress.
Sidelining our field will inevitably leave us all unprepared for the next threat
www.medpagetoday.com
December 9, 2025 at 5:59 PM
I'm an Infectious Diseases Doctor. Our Pipeline of Experts Is in Distress.
Had the opportunity to share my reflections on the challenges the ID specialty is facing on.
@medpagetoday.com
#IDSky
www.medpagetoday.com/opinion/seco...
Had the opportunity to share my reflections on the challenges the ID specialty is facing on.
@medpagetoday.com
#IDSky
www.medpagetoday.com/opinion/seco...
Reposted by Merve Tepe, PhD
Great to see @greally.bsky.social ‘s Epigenetics book in the wild at #cellbio2025 - all that pestering paid off
December 9, 2025 at 6:13 PM
Great to see @greally.bsky.social ‘s Epigenetics book in the wild at #cellbio2025 - all that pestering paid off
Reposted by Merve Tepe, PhD
#ScienceReadForSunday: Mapping Plasmodium transitions and interactions in the Anopheles female
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mapping Plasmodium transitions and interactions in the Anopheles female - Nature
Single-cell transcriptomic analyses of Plasmodium falciparum and Anopheles gambiae reveal key developmental stages, processes and factors in parasite–mosquito interactions and identify potential…
www.nature.com
December 7, 2025 at 10:15 AM
#ScienceReadForSunday: Mapping Plasmodium transitions and interactions in the Anopheles female
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Merve Tepe, PhD
A key part of @jfhevler.bsky.social's effort was development of "Thermal Tracks", a new approach to melting curve analysis that we reported in this earlier preprint:
arxiv.org/abs/2508.09659
arxiv.org/abs/2508.09659
Thermal Tracks: A Gaussian process-based framework for universal melting curve analysis enabling unconstrained hit identification in thermal proteome profiling experiments
Thermal Tracks is a Python-based statistical framework for analyzing protein thermal stability data that overcomes key limitations of existing thermal proteome profiling (TPP) work-flows. Unlike stand...
arxiv.org
December 8, 2025 at 2:35 AM
A key part of @jfhevler.bsky.social's effort was development of "Thermal Tracks", a new approach to melting curve analysis that we reported in this earlier preprint:
arxiv.org/abs/2508.09659
arxiv.org/abs/2508.09659
Reposted by Merve Tepe, PhD
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling
Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...
www.biorxiv.org
December 8, 2025 at 2:32 AM
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Merve Tepe, PhD
it boggles the mind to think this person is in control of the US biomedical research enterprise
the fate of many thousands — patients, researchers, trainees — and of America’s unquestioned status as the global leader and best hope of humankind — ought not to depend on vainglorious actors
the fate of many thousands — patients, researchers, trainees — and of America’s unquestioned status as the global leader and best hope of humankind — ought not to depend on vainglorious actors
Imagine you're overseeing the termination of clinical trials, the destruction of people's livelihoods, the dismantling of scientific research in the US, and you're complaining that Twitter didn't give you a blue check 4 years ago.
December 8, 2025 at 12:21 AM
it boggles the mind to think this person is in control of the US biomedical research enterprise
the fate of many thousands — patients, researchers, trainees — and of America’s unquestioned status as the global leader and best hope of humankind — ought not to depend on vainglorious actors
the fate of many thousands — patients, researchers, trainees — and of America’s unquestioned status as the global leader and best hope of humankind — ought not to depend on vainglorious actors
Reposted by Merve Tepe, PhD
#WHO nations extend talks on global #pathogen-sharing system to boost pandemic prep ...
| #vaccines | #diagnostics | #pandemics | #diseases | Via devdiscourse .com
| #vaccines | #diagnostics | #pandemics | #diseases | Via devdiscourse .com
WHO Nations Extend Talks on Global Pathogen-Sharing System to Boost Pandemic Prep | Health
WHO Director-General Dr Tedros Adhanom Ghebreyesus reaffirmed that the negotiations carry both enormous promise and responsibility.
www.devdiscourse.com
December 8, 2025 at 6:00 AM
#WHO nations extend talks on global #pathogen-sharing system to boost pandemic prep ...
| #vaccines | #diagnostics | #pandemics | #diseases | Via devdiscourse .com
| #vaccines | #diagnostics | #pandemics | #diseases | Via devdiscourse .com
Reposted by Merve Tepe, PhD
Do you know what #hepatitis is? ...
| #liver | #inflammation | #hepatitisB | #hepatitisC | Via @nytimes.com
| #liver | #inflammation | #hepatitisB | #hepatitisC | Via @nytimes.com
Hepatitis A, B and C: What to Know About Symptoms, Vaccines and Treatment
The disease has become a key issue in Washington. We asked doctors to explain the ABCs.
www.nytimes.com
December 7, 2025 at 10:00 PM
Do you know what #hepatitis is? ...
| #liver | #inflammation | #hepatitisB | #hepatitisC | Via @nytimes.com
| #liver | #inflammation | #hepatitisB | #hepatitisC | Via @nytimes.com
Reposted by Merve Tepe, PhD
Applications for the 2026 - 2028 AMS & EUCIC Certificate Programmes are open! These programmes are designed to strengthen your expertise in antimicrobial stewardship (AMS) & infection prevention & control.
Info:
AMS: https://ow.ly/KTWv50Xu6j6
EUCIC: https://ow.ly/Z0st50Xu6j5
#IDSky #clinmicro
Info:
AMS: https://ow.ly/KTWv50Xu6j6
EUCIC: https://ow.ly/Z0st50Xu6j5
#IDSky #clinmicro
December 7, 2025 at 12:25 PM
Applications for the 2026 - 2028 AMS & EUCIC Certificate Programmes are open! These programmes are designed to strengthen your expertise in antimicrobial stewardship (AMS) & infection prevention & control.
Info:
AMS: https://ow.ly/KTWv50Xu6j6
EUCIC: https://ow.ly/Z0st50Xu6j5
#IDSky #clinmicro
Info:
AMS: https://ow.ly/KTWv50Xu6j6
EUCIC: https://ow.ly/Z0st50Xu6j5
#IDSky #clinmicro
Reposted by Merve Tepe, PhD
WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders.
Aluminum is an ADJUVANT.
It ENHANCES your immune response to a vaccine.
That’s it.
Aluminum is an ADJUVANT.
It ENHANCES your immune response to a vaccine.
That’s it.
December 5, 2025 at 5:00 PM
WELL NOW, would you look at that? A massive, 24-YEAR-LONG study of MORE THAN 1.2 MILLION people in Denmark found NO LINK between aluminum in childhood vaccines and autism, asthma, OR chronic disorders.
Aluminum is an ADJUVANT.
It ENHANCES your immune response to a vaccine.
That’s it.
Aluminum is an ADJUVANT.
It ENHANCES your immune response to a vaccine.
That’s it.
Reposted by Merve Tepe, PhD
One of the things I teach #Micronauts is that most microbes really don't care about us. The media seems fixated on microbes that are always good, or always bad. #AngelMicrobes #DevilMicrobes #MehMicrobes. Greatest quote ever attached.
www.upi.com/Health_News/...
www.upi.com/Health_News/...
December 6, 2025 at 7:16 PM
One of the things I teach #Micronauts is that most microbes really don't care about us. The media seems fixated on microbes that are always good, or always bad. #AngelMicrobes #DevilMicrobes #MehMicrobes. Greatest quote ever attached.
www.upi.com/Health_News/...
www.upi.com/Health_News/...
Reposted by Merve Tepe, PhD
The center I'm lucky to lead at Duke just kicked off a 1 year study on ways to cut child mortality in half by 2050
It makes me sick to my stomach that RFK Jr & the Great Barrington Declaration dudes & the extreme anti-vaxx kooks are instituting policies that could drive a RISE in US child mortality
It makes me sick to my stomach that RFK Jr & the Great Barrington Declaration dudes & the extreme anti-vaxx kooks are instituting policies that could drive a RISE in US child mortality
Kennedy's zombie ACIP panel just voted to restrict hepatitis B vaccine for newborns. Experts say it will harm children for no reason. www.ms.now/news/rfk-cdc...
ACIP member Dr. Cody Meissner:
"'Do no harm' is a moral imperative. We are doing harm by changing this wording. And I vote no."
ACIP member Dr. Cody Meissner:
"'Do no harm' is a moral imperative. We are doing harm by changing this wording. And I vote no."
RFK Jr.’s CDC panel: No more hepatitis B vaccine for some newborns
The CDC's vaccine advisory panel, stocked with anti-vaccine activists and loyalists to RFK Jr., voted Friday to stop recommending a birth dose of vaccine.
www.ms.now
December 5, 2025 at 3:59 PM
The center I'm lucky to lead at Duke just kicked off a 1 year study on ways to cut child mortality in half by 2050
It makes me sick to my stomach that RFK Jr & the Great Barrington Declaration dudes & the extreme anti-vaxx kooks are instituting policies that could drive a RISE in US child mortality
It makes me sick to my stomach that RFK Jr & the Great Barrington Declaration dudes & the extreme anti-vaxx kooks are instituting policies that could drive a RISE in US child mortality
Reposted by Merve Tepe, PhD
An eight-decade partnership between universities and the federal government made U.S. science preeminent.
It took Trump less than a year to shred that crucial alliance.
It took Trump less than a year to shred that crucial alliance.
American Science, Shattered
An eight-decade partnership between universities and the federal government made U.S. science preeminent. It took Trump less than a year to shred that
www.statnews.com
December 5, 2025 at 1:19 AM
An eight-decade partnership between universities and the federal government made U.S. science preeminent.
It took Trump less than a year to shred that crucial alliance.
It took Trump less than a year to shred that crucial alliance.
Reposted by Merve Tepe, PhD
Reposted by Merve Tepe, PhD
Wow. Many of the medical societies liaisons left the ACIP meeting. They are telling us the ACIP meeting isn’t worth their time because it is not based in science and evidence. Says it all
December 4, 2025 at 7:23 PM
Wow. Many of the medical societies liaisons left the ACIP meeting. They are telling us the ACIP meeting isn’t worth their time because it is not based in science and evidence. Says it all
Reposted by Merve Tepe, PhD
If you're an expert in your field but still occasionally feel a tinge of imposter syndrome, just have a look at some of the current ACIP lineup.
December 4, 2025 at 6:57 PM
If you're an expert in your field but still occasionally feel a tinge of imposter syndrome, just have a look at some of the current ACIP lineup.
Reposted by Merve Tepe, PhD
Shocking that he doesn't seem to be delivering neutral, unbiased data we all can trust.
December 4, 2025 at 7:07 PM
Shocking that he doesn't seem to be delivering neutral, unbiased data we all can trust.
Reposted by Merve Tepe, PhD
New Osterholm Update podcast episode! @mtosterholm & @cvdall discuss changes to the CDC's vaccines-autism page, this week's ACIP (CDC vax advisory) meeting, a recent infant botulism outbreak, & possible C. difficile vaccines
www.cidrap.umn.edu/a...
www.cidrap.umn.edu/a...
December 4, 2025 at 7:07 PM
New Osterholm Update podcast episode! @mtosterholm & @cvdall discuss changes to the CDC's vaccines-autism page, this week's ACIP (CDC vax advisory) meeting, a recent infant botulism outbreak, & possible C. difficile vaccines
www.cidrap.umn.edu/a...
www.cidrap.umn.edu/a...
Reposted by Merve Tepe, PhD
Evergreen
Bless all of you who are listening to the fACIP meeting right now, I just can't...
(as in "finsta", which I hear is a thing the youths used to say)
(as in "finsta", which I hear is a thing the youths used to say)
December 4, 2025 at 7:10 PM
Evergreen
Reposted by Merve Tepe, PhD
The US is close to an institutional collapse across multiple public health agencies. Trump/RFK have purged anyone with expertise, many have fled and they’ve been replaced w functionaries who are either incompetent or malicious. I don’t think many understand how close to the edge we are right now.
a night time view of a city with a few buildings lit up
ALT: a night time view of a city with a few buildings lit up
media.tenor.com
December 4, 2025 at 7:06 PM
The US is close to an institutional collapse across multiple public health agencies. Trump/RFK have purged anyone with expertise, many have fled and they’ve been replaced w functionaries who are either incompetent or malicious. I don’t think many understand how close to the edge we are right now.
Reposted by Merve Tepe, PhD
Petition to rename ACIP “The Morgue” because science is dead in that room.
December 4, 2025 at 4:10 PM
Petition to rename ACIP “The Morgue” because science is dead in that room.
Reposted by Merve Tepe, PhD
OPEN SPOT ALERT! There is an ID fellowship spot available at Boston Medical Center. Incredible team, sane workload (including consult caps and non-teaching service). Highly recommended if you're interested in TB/global health, HIV, SUD, or AMR/stewardship. Message me if interested! #IDsky #MedSky
December 3, 2025 at 8:30 PM