#PostInfectious
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maureviv.bsky.social
Not symptoms per se, but the well known postinfectious origin, fatigue, and also lupus and RF are heavily antibody-mediated
December 9, 2025 at 4:50 PM
castltrastondrs.bsky.social
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
2. Immune-Mediated and Autoimmune Mechanisms
- Postinfectious parkinsonism is often attributed to autoimmune processes that produce neurologic complications and delayed damage to the nervous system
December 4, 2025 at 7:50 AM
lucibee.bsky.social
3. Then we have Whitty's quote from his 4th witness statement (para 12.2).

How can it possibly be *unhelpful* to prepare for a post-infectious syndrome?

covid19.public-inquiry.uk/documents/in...
Extract from Chris Whitty's fourth witness statement reads: 12.2. The fact that post viral syndromes occur, and indeed postinfectious syndromes more widely, does not however mean that Long COVID as it manifested was predictable. Different infections and different situations leading to different syndromes are common. Some very severe diseases rarely have post infection syndromes whilst other relatively trivial infections can have quite common and prolonged ones. It is therefore both true, but also largely unhelpful, to say there might be a postinfectious syndrome'. In itself this would not obviously have helped us respond in the initial period.
November 22, 2025 at 4:01 PM
apresj20.bsky.social
#ApresJ20 #CovidLong #LongCovid
#EncéphalomyéliteMyalgique #EM #MECFS #Lyme #Alzheimer
#PostInfectious #PersistentVirus #ViralPersistence #IACCs #PostInfectieux #BiomedicalResearch #ClinicalTrials #FallSymposium2025 #PolyBio #UCSF #Karolinska #MountSinai #DemystifyingLongCovid
November 17, 2025 at 3:20 PM
chantalbritt.bsky.social
The motion for a Swiss Strategy for postinfectious conditions was approved! We , the patient organisations for long covid and myalgic encephalomyelitis thank all who made this possible! What a day!
September 18, 2025 at 10:42 AM
drmenzmd.bsky.social
SSPE is EXACTLY the type of complication I always talk about when discussing vaccines. It’s not just about the disease itself, but the postinfectious sequelae.
shematologist.medsky.social Shematologist, MD @shematologist.medsky.social · Sep 12
Absolutely tragic.

No one should be getting, let alone dying of measles these days.

#VaccinesSaveLives
cnn.com CNN @cnn.com · Sep 12
A school-age child in Los Angeles County who had measles as an infant has died of a rare complication, the county health department said.
September 12, 2025 at 3:10 AM
beten0ire.bsky.social
Except, they are correct.

The Challenge of Long COVID: Is the Pandemic Really Over?
journals.sagepub.com/doi/abs/10.1...
“The best estimates are that millions of people have long COVID. Despite the declining incidence of COVID-19, the low case fatality of long COVID suggests that its prevalence is poised to continue to grow. This increasing prevalence of long COVID presents a challenge for the public health sector. Here, we examine the public health implications of long COVID. We offer policy recommendations, including ending congratulatory talk that the pandemic is over, encouraging more focused attention from the United States and global nongovernmental organizations, and establishing a multinational research initiative to better understand and respond to long COVID and other postviral and postinfectious chronic conditions. Although COVID-19 may not be as widespread and disruptive as in the early months of the pandemic, it would be a mistake to presume that, because the acute crisis is behind us, the pandemic is past. Long COVID is an ongoing public health threat and merits our concern.”
September 3, 2025 at 7:17 PM
beten0ire.bsky.social
This is from 2025:

The Challenge of Long COVID: Is the Pandemic Really Over?
journals.sagepub.com/doi/abs/10.1...
“The best estimates are that millions of people have long COVID. Despite the declining incidence of COVID-19, the low case fatality of long COVID suggests that its prevalence is poised to continue to grow. This increasing prevalence of long COVID presents a challenge for the public health sector. Here, we examine the public health implications of long COVID. We offer policy recommendations, including ending congratulatory talk that the pandemic is over, encouraging more focused attention from the United States and global nongovernmental organizations, and establishing a multinational research initiative to better understand and respond to long COVID and other postviral and postinfectious chronic conditions. Although COVID-19 may not be as widespread and disruptive as in the early months of the pandemic, it would be a mistake to presume that, because the acute crisis is behind us, the pandemic is past. Long COVID is an ongoing public health threat and merits our concern.”
September 3, 2025 at 7:10 PM
tomkindlon.bsky.social
🧵
New US News Release

Study Reveals Details of Overactive Immune System in Patients with Chronic Fatigue Syndrome (ME/CFS)

www.eurekalert.org/news-release...

"Patients with [ME/CFS] have heightened innate immune responses to bacteria, viruses & fungi"

#ChronicFatigueSyndrome #MEcfs #CFS #PwME
1/
News Release 1-Sep-2025 Study Reveals Details of Overactive Immune System in Patients with Chronic Fatigue Syndrome (ME/CFS) Peer-Reviewed Publication Columbia University's Mailman School of Public Health Patients with chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) have heightened innate immune responses to bacteria, viruses and fungi. While these responses are essential to fight infection, they can cause damage when unchecked. Led by researchers at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health with a multicenter team of leading ME/CFS researchers, the new study reveals molecular-level details into the syndrome’s lasting effects on inflammation and immune response that could inform the development of targeted therapeutic interventions to reduce symptoms of ME/CFS and other postinfectious syndromes such as post-treatment Lyme disease and Long COVID. Study findings are published in the journal npj Metabolic Health and Disease.
September 1, 2025 at 1:43 PM
tomkindlon.bsky.social
"Drs Brittany Adler, Anthony Komaroff, Brayden Yellman & Lisa Sanders weigh in on how the health care system better can facilitate care for patients with postinfectious illnesses" by @miriametucker.bsky.social

www.medscape.com/viewarticle/...

Screenshot from Science for ME update
#LongCovid #MEcfs
Medscape Where Is the Medical Home for Postinfectious Illness? Good article by Miriam Tucker where Brittany L. Adler, MD, Anthony L. Komaroff, MD, Brayden Yellman, MD and Lisa Sanders, MD weigh in on how the health care system better can facilitate care for patients with postinfectious illnesses.
August 25, 2025 at 12:35 AM
davetuller1.bsky.social
News bits: Update on Keystone gathering from
@thesicktimes.org; Severe ME Day video from
@anilvanderzee.bsky.social; Medscape article from @miriametucker.bsky.social on fractured care for postinfectious illness. virology.ws/2025/08/21/t...
Trial By Error: Keystone Gathering Update; Anil's Severe ME Day Video; Fractured Care for Post-Infectious Illness | Virology Blog
By David Tuller, DrPH Keystone gathering round-up from Sick Times Many prominent Long COVID researchers gathered in Santa Fe, New Mexico, last week to discu ...
virology.ws
August 21, 2025 at 5:39 PM
ahimsa-pdx.disabled.social.ap.brid.gy
From Medscape:

"Where Is the Medical Home for Postinfectious Illness?"

https://www.medscape.com/viewarticle/where-medical-home-postinfectious-illness-2025a1000m05

"Many can trace these symptoms to a specific infection… [but] infectious trigger may not have been confirmed or recognized at the […]
Original post on disabled.social
disabled.social
August 20, 2025 at 11:03 PM
adrs.bsky.social
"Indeed, people with postinfectious chronic illness often receive multiple diagnoses from different clinicians, but there is no dedicated space for them in the current healthcare system, and as a result, their care is often suboptimal."
August 20, 2025 at 5:09 PM
bhanlon15.bsky.social
Medscape: Where Is the Medical Home for Postinfectious Illness?

"COVID pandemic brought a surge of more patients with POTS & infection-associated chronic illness. What had once felt like a rare or niche diagnosis now seemed to be everywhere, impossible to ignore"

www.medscape.com/viewarticle/...
Where Is the Medical Home for Postinfectious Illness?
A rheumatologist calls for greater awareness among her colleagues but also emphasizes that these patients require multidisciplinary care.
www.medscape.com
August 20, 2025 at 1:57 PM
valebodi.bsky.social
nongovernmental organizations, and establishing a multinational research initiative to better understand and respond to long COVID and other postviral and postinfectious chronic conditions.
August 18, 2025 at 6:51 PM
ycpharmacy.bsky.social
ส่วนใหญ่ไอหลังหาย #ไข้หวัด (Postinfectious cough) ✅ บางครั้งใช้ยาระงับไอ+ยาลดคัดจมูกแบบสั้นๆ #ไอเรื้อรัง (> 8 สัปดาห์) เจอบ่อยจาก #ภูมิแพ้ , #น้ำมูกไหลลงคอ , #หอบหืด , #กรดไหลย้อน ✅ รักษาตามสาเหตุ เช่น สเปรย์จมูก, ยาต้านฮีสตามีน, ล้างจมูก 🎯
August 17, 2025 at 11:36 PM
chantalbritt.bsky.social
The commission of the upper house unanimously recommended to approve the motion for a national strategy for postinfectious conditions. The strategy would provide a basis to improve healthcare, research and social security. @longcovidch.bsky.social

long-covid-info.ch/news/5679/
SGK Kommission des Ständerates beantragt einstimmig die Nationale Strategie anzunehmen - Long Covid Schweiz
Die Kommission für soziale Sicherheit und Gesundheit des Ständerates (SGK-S) beantragt einstimmig, die Motion für eine „Nationale Strategie zur Verbesserung der gesundheitlichen Situation von Menschen...
long-covid-info.ch
August 15, 2025 at 10:47 AM
castltrastondrs.bsky.social
www.nature.com/articles/s41...

www.mdpi.com/2076-3425/15...

pmc.ncbi.nlm.nih.gov/articles/PMC...

www.frontiersin.org/journals/imm...

link.springer.com/article/10.1...

www.sciencedirect.com/science/arti...

onlinelibrary.wiley.com/doi/10.1111/...
Advanced age increases CNS infection and lethality following respiratory coronavirus infection, coupled with increased infiltration of activated effector (Teff) CD8+ T cells into the CNS. Aged Teff are not antigen specific, and do not effectively transition to long‐lived protective TRM, leaving aged mice more susceptible to secondary viral rechallenge. However, activation of Teff and reactivation of TRM contributes to neuronal death and postinfectious cognitive impairment in both adult and aged mice, albeit with increased severity in aged individuals. Pathophysiological mechanisms implicated in neuropsychiatric L-C19 manifestation (Inline graphic—C19)The mechanisms underlying the neuropsychiatric manifestations of L-C19 are complex and interact with each other: 1. Persistent systemic inflammation and cytokine storms: In L-C19 patients, SARS-CoV-2 creates immunological irregularities, which trigger neuroinflammatory responses by activating microglia cells and driving the development of brain white matter abnormalities and microvascular damage. 2. Neuroinvasiveness, neurotropism, and neurovirulence: Through the ACE2 receptor, SARS-CoV-2 shows inherent neuroinvasive capabilities, enabling it to attack neuronal cells and set off cellular death in nearby tissue. 3. Blood–brain barrier (BBB) disruption: Brain injury from SARS-CoV-2 causes integrity damage to the blood–brain barrier, which results in higher permeability and allows blood component leakage, along with immune cell transmission throughout brain parenchyma. 4. Prolonged neuroinflammation: The brain experiences a persistent inflammatory state due to cytokines and chemokines that persistently activate brain tissue. 5. Microvasculitis: Brain inflammation persists in C-19 patients, leading to microvascular damage throughout the brain. 6. Prolonged endothelial dysfunction, platelet activation, and enhanced thrombin generation: These factors, in addition to others, may disrupt brain regions’ functioning in patients experiencing neuro-L-C19. 7. Silent hypoxia contributes to brain damage while encouraging cytokine storms through inflammatory mediators, which cause severe damage to the endothelial system. 8. Dysregulated levels of neurotransmitters like serotonin and dopamine: Brain dysfunction could lead to neurological and psychological symptoms during L-C19 development. 9. Amyloid aggregation: Numerous viral proteins demonstrate the capacity to produce amyloid proteins. 10. Neuronal death: The two biological mechanisms that explain neuronal damage in L-C19 are ast…
July 22, 2025 at 3:43 PM
dkimor.bsky.social
In case you thought measles is no big deal: “The central nervous system complications of measles can occur within days or years of acute infection and are often severe. These include primary measles encephalitis, acute postinfectious measles encephalomyelitis, measles inclusion body encephalitis…”
phillewis.bsky.social Phil Lewis @phillewis.bsky.social · Jul 9
ATLANTA (AP) — The US is having its worst year for measles spread in more than three decades, CDC says.
July 9, 2025 at 11:07 PM
fascinatorfun.bsky.social
“We have previously reported that patients with postinfectious Lyme arthritis often harbor the peptidoglycan (PG) cell wall of Borrelia burgdorferi, the Lyme disease agent, in the synovial fluid of their inflamed joints after treatment”
June 26, 2025 at 8:25 AM
meverenigingnl.bsky.social
That is in part because of the poor terminology. None of these terms are accurate. To be accurate and get more recognition, use proper terms. So covid and ME for the infectious diseases, and postinfectious syndrome (PIS) for the unexplained residual issues (postcovid, post-ME, post-ebola, etc.).
June 21, 2025 at 1:51 PM
vasculitides.bsky.social
Postinfectious manifestations in two pediatric female X-linked carriers of chronic granulomatous disease
https://pubmed.ncbi.nlm.nih.gov/40411120
Image
May 26, 2025 at 10:05 AM
pathologyoutlines.bsky.social
(Image Quiz, continued)

A. Lupus nephritis
B. Membranous glomerulonephritis
C. Minimal change disease
D. Postinfectious glomerulonephritis
E. Renal amyloidosis

Answer linked in the comments.

#Pathology #ImageQuiz #PathologyOutlines #Diagnosis
May 13, 2025 at 5:21 PM
chantalbritt.bsky.social
It was a pleasure talking about the long covid mode project developed by European network organisation Long COVID Europe to raise awareness for long covid, myalgic encephalomyelitis and other postinfectious conditions.
May 7, 2025 at 7:39 PM