1️⃣0️⃣📖 Paper: Shahbaz et al., Cell Reports Medicine (2025)
“Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in Long Covid patients with ME/CFS.”
www.cell.com/cell-reports...
“Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in Long Covid patients with ME/CFS.”
www.cell.com/cell-reports...
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
Shahbaz et al. find that female long COVID patients with ME/CFS exhibit heightened
inflammation, altered hematopoiesis, disrupted hormone levels, and neuroinflammatory
gene signatures. In parallel, ou...
www.cell.com
November 8, 2025 at 11:47 AM
1️⃣0️⃣📖 Paper: Shahbaz et al., Cell Reports Medicine (2025)
“Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in Long Covid patients with ME/CFS.”
www.cell.com/cell-reports...
“Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in Long Covid patients with ME/CFS.”
www.cell.com/cell-reports...
Nature research paper: Transcriptomic and spatial organization of telencephalic GABAergic neurons
go.nature.com/43fLcE5
go.nature.com/43fLcE5
Transcriptomic and spatial organization of telencephalic GABAergic neurons - Nature
Long-distance migration and dispersion is a common characteristic of nearly all classes of telencephalic GABAergic neurons, which diversify extensively after birth in the cortex and striatum, but show limited postnatal changes in the septum, preoptic area and pallidum.
go.nature.com
November 8, 2025 at 12:24 PM
Nature research paper: Transcriptomic and spatial organization of telencephalic GABAergic neurons
go.nature.com/43fLcE5
go.nature.com/43fLcE5
Cell Reports Medicine: 'Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS'
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
Shahbaz et al. find that female long COVID patients with ME/CFS exhibit heightened
inflammation, altered hematopoiesis, disrupted hormone levels, and neuroinflammatory
gene signatures. In parallel, ou...
www.cell.com
November 7, 2025 at 10:33 PM
Cell Reports Medicine: 'Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS'
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
www.cell.com/cell-re...
1/10
www.cell.com/cell-re...
1/10
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
Shahbaz et al. find that female long COVID patients with ME/CFS exhibit heightened
inflammation, altered hematopoiesis, disrupted hormone levels, and neuroinflammatory
gene signatures. In parallel, our study identifies sex-specific immune and hormonal
biomarkers that correlate with clinical symptoms, supporting the need for tailored
therapeutic strategies, including consideration of hormone replacement therapy.
www.cell.com
November 10, 2025 at 3:17 PM
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
www.cell.com/cell-re...
1/10
www.cell.com/cell-re...
1/10
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Transcriptomic Analysis of the Human Habenula in Schizophrenia | American Journal of Psychiatry
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
doi.org
November 4, 2025 at 9:31 PM
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
2/
Press release:
www.ualberta.ca/en/folio/202...
Paper:
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
www.cell.com/cell-reports...
#LongCovid #cfs
Press release:
www.ualberta.ca/en/folio/202...
Paper:
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
www.cell.com/cell-reports...
#LongCovid #cfs
November 7, 2025 at 6:31 PM
2/
Press release:
www.ualberta.ca/en/folio/202...
Paper:
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
www.cell.com/cell-reports...
#LongCovid #cfs
Press release:
www.ualberta.ca/en/folio/202...
Paper:
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
www.cell.com/cell-reports...
#LongCovid #cfs
A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus https://www.biorxiv.org/content/10.1101/2025.11.05.685843v1
November 6, 2025 at 11:16 PM
A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus https://www.biorxiv.org/content/10.1101/2025.11.05.685843v1
Single-cell resolution spatial transcriptomic signature of the retrosplenial cortex during memory consolidation
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Single-cell resolution spatial transcriptomic signature of the retrosplenial cortex during memory consolidation - Molecular Psychiatry
Molecular Psychiatry - Single-cell resolution spatial transcriptomic signature of the retrosplenial cortex during memory consolidation
www.nature.com
November 4, 2025 at 5:49 PM
Single-cell resolution spatial transcriptomic signature of the retrosplenial cortex during memory consolidation
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas https://www.biorxiv.org/content/10.1101/2025.11.03.686234v1
November 4, 2025 at 3:48 PM
Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas https://www.biorxiv.org/content/10.1101/2025.11.03.686234v1
A plasma membrane receptor complex mediates early heat-responsive signaling to trigger nuclear transcriptomic reprogramming in Arabidopsis #research #MolecularPlant cell.com/molecular-pl...
November 1, 2025 at 11:53 AM
A plasma membrane receptor complex mediates early heat-responsive signaling to trigger nuclear transcriptomic reprogramming in Arabidopsis #research #MolecularPlant cell.com/molecular-pl...
Comparative #transcriptomic analysis of #Chinese #cabbage’s defense responses to #Alternaria brassicae
🥬https://doi.org/10.1016/j.jia.2025.06.024
✏️Prof. Baohua Li team from Northwest A&F University
🔗Chinese tweet shorturl.at/cxQiC
#horticulture #plantsci
🥬https://doi.org/10.1016/j.jia.2025.06.024
✏️Prof. Baohua Li team from Northwest A&F University
🔗Chinese tweet shorturl.at/cxQiC
#horticulture #plantsci
November 4, 2025 at 8:35 AM
Comparative #transcriptomic analysis of #Chinese #cabbage’s defense responses to #Alternaria brassicae
🥬https://doi.org/10.1016/j.jia.2025.06.024
✏️Prof. Baohua Li team from Northwest A&F University
🔗Chinese tweet shorturl.at/cxQiC
#horticulture #plantsci
🥬https://doi.org/10.1016/j.jia.2025.06.024
✏️Prof. Baohua Li team from Northwest A&F University
🔗Chinese tweet shorturl.at/cxQiC
#horticulture #plantsci
Spatiotemporal transcriptomic and metabolomic landscapes of wild soybean seed development reveal regulatory mechanisms of nutrient accumulation #research #PlantCommunications cell.com/plant-commun...
November 1, 2025 at 11:51 AM
Spatiotemporal transcriptomic and metabolomic landscapes of wild soybean seed development reveal regulatory mechanisms of nutrient accumulation #research #PlantCommunications cell.com/plant-commun...
Integrated #transcriptomic and metabolomic analyses reveal a novel mechanism of resistance to #Colletotrichum fructicola in #pear
🍐https://doi.org/10.1016/j.jia.2024.12.041
#horticulture #plantsci
🍐https://doi.org/10.1016/j.jia.2024.12.041
#horticulture #plantsci
October 31, 2025 at 7:21 AM
Integrated #transcriptomic and metabolomic analyses reveal a novel mechanism of resistance to #Colletotrichum fructicola in #pear
🍐https://doi.org/10.1016/j.jia.2024.12.041
#horticulture #plantsci
🍐https://doi.org/10.1016/j.jia.2024.12.041
#horticulture #plantsci
COL8A1 #EndMT
Human aortic endothelial cells with immobilized, but not soluble, COL8A1 proteins▶️
Elongated morphology
⏫Endothelial/angiogenic transcriptomic features
TNFα-induced #EndMT ⏫by siCOL8A1, ⏬by lentiviral COL8A1
@jeffhsumd.bsky.social #AJPHC 2025
journals.physiology.org/doi/abs/10.1...
Human aortic endothelial cells with immobilized, but not soluble, COL8A1 proteins▶️
Elongated morphology
⏫Endothelial/angiogenic transcriptomic features
TNFα-induced #EndMT ⏫by siCOL8A1, ⏬by lentiviral COL8A1
@jeffhsumd.bsky.social #AJPHC 2025
journals.physiology.org/doi/abs/10.1...
October 31, 2025 at 7:04 PM
COL8A1 #EndMT
Human aortic endothelial cells with immobilized, but not soluble, COL8A1 proteins▶️
Elongated morphology
⏫Endothelial/angiogenic transcriptomic features
TNFα-induced #EndMT ⏫by siCOL8A1, ⏬by lentiviral COL8A1
@jeffhsumd.bsky.social #AJPHC 2025
journals.physiology.org/doi/abs/10.1...
Human aortic endothelial cells with immobilized, but not soluble, COL8A1 proteins▶️
Elongated morphology
⏫Endothelial/angiogenic transcriptomic features
TNFα-induced #EndMT ⏫by siCOL8A1, ⏬by lentiviral COL8A1
@jeffhsumd.bsky.social #AJPHC 2025
journals.physiology.org/doi/abs/10.1...
CFMF: A Clustering-Free Cell Marker Finder for Single-Cell Transcriptomic Data https://www.biorxiv.org/content/10.1101/2025.10.26.683836v1
October 28, 2025 at 6:47 PM
CFMF: A Clustering-Free Cell Marker Finder for Single-Cell Transcriptomic Data https://www.biorxiv.org/content/10.1101/2025.10.26.683836v1
omicML: An Integrative Bioinformatics and Machine Learning Framework for Transcriptomic Biomarker Identification https://www.biorxiv.org/content/10.1101/2025.10.25.684517v1
October 28, 2025 at 3:47 AM
omicML: An Integrative Bioinformatics and Machine Learning Framework for Transcriptomic Biomarker Identification https://www.biorxiv.org/content/10.1101/2025.10.25.684517v1
🚀 Our new Science paper is out (w/ B DeMeo, D Burkhardt, A Shalek, M Cortes): www.science.org/doi/10.1126/...
We show that active learning + transcriptomic perturbations can guide which exps to run next, boosting phenotypic hit rates >13x. AI not just predicting bio, but designing it. 🔁
We show that active learning + transcriptomic perturbations can guide which exps to run next, boosting phenotypic hit rates >13x. AI not just predicting bio, but designing it. 🔁
October 25, 2025 at 1:24 PM
🚀 Our new Science paper is out (w/ B DeMeo, D Burkhardt, A Shalek, M Cortes): www.science.org/doi/10.1126/...
We show that active learning + transcriptomic perturbations can guide which exps to run next, boosting phenotypic hit rates >13x. AI not just predicting bio, but designing it. 🔁
We show that active learning + transcriptomic perturbations can guide which exps to run next, boosting phenotypic hit rates >13x. AI not just predicting bio, but designing it. 🔁
Integrated genomic and transcriptomic profiling of glioblastoma reveals ecDNA-driven heterogeneity and microenvironmental reprogramming
Integrated genomic and transcriptomic profiling of glioblastoma reveals ecDNA-driven heterogeneity and microenvironmental reprogramming
Tang et al. provide a comprehensive genomic and transcriptomic characterization of extrachromosomal DNA (ecDNA) in glioblastoma. They reveal that EGFR ecDNA shapes transcriptional subtypes and reprograms the tumor microenvironment by stabilizing metabolically active tumor-associated macrophages. These findings uncover mechanistic links between ecDNA architecture and glioblastoma progression, highlighting potential therapeutic vulnerabilities.
dlvr.it
October 25, 2025 at 2:38 PM
Integrated genomic and transcriptomic profiling of glioblastoma reveals ecDNA-driven heterogeneity and microenvironmental reprogramming
🚨 New paper out in #JCP-A @springernature.com "Divergent sensory transcriptomic profiles in positive and negative learning in Bicyclus Anynana butterflies" by Yi Teng Ter & Erica Westerman #Neurogenomics #VisualLearning #Lepidoptera 🧪🧠🦋
↘️ link.springer.com/article/10.1... ↙️
↘️ link.springer.com/article/10.1... ↙️
Divergent sensory transcriptomic profiles in positive and negative learning in Bicyclus Anynana butterflies - Journal of Comparative Physiology A
Journal of Comparative Physiology A - Mate preference learning, where individuals learn to prefer or avoid specific phenotypes during mate selection, is pervasive across animal taxa and influences...
link.springer.com
October 23, 2025 at 12:06 AM
🚨 New paper out in #JCP-A @springernature.com "Divergent sensory transcriptomic profiles in positive and negative learning in Bicyclus Anynana butterflies" by Yi Teng Ter & Erica Westerman #Neurogenomics #VisualLearning #Lepidoptera 🧪🧠🦋
↘️ link.springer.com/article/10.1... ↙️
↘️ link.springer.com/article/10.1... ↙️
🔬🌹 RESEARCH 🌹🔬
Transcriptomic and functional analyses reveal a molecular framework of Botrytis cinerea colonization in rose, which integrates multiple fungal physiological processes and manipulation of plant cells - Li et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Transcriptomic and functional analyses reveal a molecular framework of Botrytis cinerea colonization in rose, which integrates multiple fungal physiological processes and manipulation of plant cells - Li et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
October 23, 2025 at 1:11 PM
🔬🌹 RESEARCH 🌹🔬
Transcriptomic and functional analyses reveal a molecular framework of Botrytis cinerea colonization in rose, which integrates multiple fungal physiological processes and manipulation of plant cells - Li et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
Transcriptomic and functional analyses reveal a molecular framework of Botrytis cinerea colonization in rose, which integrates multiple fungal physiological processes and manipulation of plant cells - Li et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
There's something else we want to highlight about this paper: all the single-cell transcriptomic atlases can be freely browsed through an interactive database (by @aelek.bsky.social). This includes 3 coral species: Oculina, Stylophora pistillata & Acropora millepora 🪸
sebelab.crg.eu/multicoral-s...
sebelab.crg.eu/multicoral-s...
October 20, 2025 at 5:16 PM
There's something else we want to highlight about this paper: all the single-cell transcriptomic atlases can be freely browsed through an interactive database (by @aelek.bsky.social). This includes 3 coral species: Oculina, Stylophora pistillata & Acropora millepora 🪸
sebelab.crg.eu/multicoral-s...
sebelab.crg.eu/multicoral-s...
Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma https://www.biorxiv.org/content/10.1101/2025.10.19.683298v1
October 20, 2025 at 3:30 AM
Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma https://www.biorxiv.org/content/10.1101/2025.10.19.683298v1
This is not generative AI, this is actually machine learning. The trainee's head is highly specialized and focused in a specific area of knowledge.
transcriptomic data, biological text, and metadata
And again, even with this, they do not think, they cannot provide intelligence.
transcriptomic data, biological text, and metadata
And again, even with this, they do not think, they cannot provide intelligence.
October 17, 2025 at 5:20 PM
This is not generative AI, this is actually machine learning. The trainee's head is highly specialized and focused in a specific area of knowledge.
transcriptomic data, biological text, and metadata
And again, even with this, they do not think, they cannot provide intelligence.
transcriptomic data, biological text, and metadata
And again, even with this, they do not think, they cannot provide intelligence.
'This system provides us with a manipulable model that allows for controlled cytokine exposures of multiple timescales and concentrations, with both transcriptomic and glycomic readouts'
#immunology #preprint #glycobiology
www.biorxiv.org/content/10.1...
#immunology #preprint #glycobiology
www.biorxiv.org/content/10.1...
Multivariate analysis of glycogenes reveals coordinated regulation of immunoglobulin glycosylation in an immortalized human B cell system
While neutralizing ability has traditionally been considered the most important antibody function, appreciation has grown for Fc-mediated ‘extra-neutralizing’ functions, which are shaped by IgG glycos...
www.biorxiv.org
October 17, 2025 at 11:14 AM
'This system provides us with a manipulable model that allows for controlled cytokine exposures of multiple timescales and concentrations, with both transcriptomic and glycomic readouts'
#immunology #preprint #glycobiology
www.biorxiv.org/content/10.1...
#immunology #preprint #glycobiology
www.biorxiv.org/content/10.1...
(2/5)
In our latest work, we established persistent viral infections to examine their impact on this model organism.
We followed survival and other life history traits, and we also performed a transcriptomic analysis over time… (The data is available for you to play with it! 💻🧬🪰)
In our latest work, we established persistent viral infections to examine their impact on this model organism.
We followed survival and other life history traits, and we also performed a transcriptomic analysis over time… (The data is available for you to play with it! 💻🧬🪰)
October 17, 2025 at 2:07 PM
(2/5)
In our latest work, we established persistent viral infections to examine their impact on this model organism.
We followed survival and other life history traits, and we also performed a transcriptomic analysis over time… (The data is available for you to play with it! 💻🧬🪰)
In our latest work, we established persistent viral infections to examine their impact on this model organism.
We followed survival and other life history traits, and we also performed a transcriptomic analysis over time… (The data is available for you to play with it! 💻🧬🪰)