Mike Ando
dmikeando.bsky.social
Mike Ando
@dmikeando.bsky.social
ML @ Calico. Previously at Google Research and UCSF. Still amazed and excited by the power of microscopy to understand biology.
Pinned
There has been enough interest that we are on to Microscopy Starter Pack #2. Still open to who to include, including yourself!

go.bsky.app/DA4LAjJ
Reposted by Mike Ando
@ninaluong.bsky.social is really upping her costume game this year. And she can still work in it!
October 31, 2025 at 3:21 PM
Reposted by Mike Ando
October 31, 2025 at 4:21 PM
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🎃A fluorescent turmeric jack-o'-lantern!🎃
I filled a flat-bottom flask with turmeric extract. Jordan Tanen drew the face.🖊️ #FluorescenceFriday #SciArt #SciComm #RealTimeChem #ChemArt
October 24, 2025 at 1:00 PM
Reposted by Mike Ando
The #OME-Zarr RFC-5 proposal allows you to transform multiple images into the same coordinateSystem. Trying this out with napari at github.com/will-moore/n.... Cool that you can offset T-dimension as well as XYZ!
October 20, 2025 at 1:00 PM
Reposted by Mike Ando
🎃Welcome to my fluorescent pumpkin patch!🎃
Jack-O-Lanterns are pipette tips filled with 😈 lucifer yellow, fluorescein, or rhodamine 101.🎃
🌝 #FluorescenceFriday #PipetteArt #SciArt #ChemArt #SciComm #HappyHalloween #Halloween 🎃
October 17, 2025 at 12:38 PM
Reposted by Mike Ando
New #NeurIPS2025 paper: how should we evaluate machine learning models without a large, labeled dataset? We introduce Semi-Supervised Model Evaluation (SSME), which uses labeled and unlabeled data to estimate performance! We find SSME is far more accurate than standard methods.
October 17, 2025 at 4:29 PM
Reposted by Mike Ando
Going through some Erdős problems that Mark Sellke and Mehtaab Sawhney found had already been solved using GPT5 pro for search. More precisely, these were listed as open, but solutions to them already existed in the literature, but not recognized as such. Quite remarkable.

One example: [+]
October 18, 2025 at 5:17 AM
Reposted by Mike Ando
For this #FluorescenceFriday 🔬
a cryosection of a dissected zebrafish gill, stained with phalloidin (orange) and DAPI (blue-ish).

#Zebrafish #DevBio #Microscopy
October 17, 2025 at 3:15 PM
Reposted by Mike Ando
what do you mean i have to submit an abstract now for a presentation in april?
October 18, 2025 at 2:27 PM
Reposted by Mike Ando
Today for #FluorescenceFriday I’m sharing a 👻Halloween-themed🎃 neural crest explant “web of cells” from Julia Godinez, a 4th year @ucdavis.bsky.social graduate student in the lab. She is studying mechanisms driving conserved and divergent cranial neural crest migration and differentiation. #DevBio
October 17, 2025 at 8:21 PM
Reposted by Mike Ando
As part of our monthly meeting, we do a run-down of all* the new #bioimageanalysis tools that have been published in the last couple of weeks on BioRxiv**, so I thought I'd start sharing here as well.

*I will miss some, apologies if I miss your paper
October 17, 2025 at 7:17 AM
Reposted by Mike Ando
Stages of CV research work

1. Denial
2. Anger
3. Bargaining
4. Depression
5. Manual data labeling
6. ???
7. PROFIT
October 15, 2025 at 3:41 PM
Reposted by Mike Ando
Big news! Our week-long #bioimageanalysis bootcamp is BACK! Learn how to think about bioimage analysis like the pros do, learn what corrections you should (and shouldn't!) apply to your images, learn open source tools, and more. Apply NOW at broad.io/BAB3 for our January 2026 course!
October 14, 2025 at 9:31 PM
Reposted by Mike Ando
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
October 14, 2025 at 10:56 AM
Reposted by Mike Ando
The future of High-Content Imaging has arrived.

-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!

See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
October 13, 2025 at 12:44 AM
Reposted by Mike Ando
Threw away the pellet
In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

rm -rf ~/
"The chancellor approved it"
October 12, 2025 at 1:26 PM
Reposted by Mike Ando
#SpatialOmics

MCMICRO
Multiple Choice Microscopy pipeline
mcmicro.org

Multi-channel whole-slide images▶️
Single-cell data + Spatial Feature Tables

Multimodal (CyCIF CODEX mIHC) registration + HE IMC MIBI

#NatMethods 2022
www.nature.com/articles/s41...
October 12, 2025 at 12:21 PM
Reposted by Mike Ando
The connectome of the entire male Drosophila central nervous system is out!! Acquired using FIB-SEM @ 8x8x8nm, we aligned 7.5 mio 2D images aligned into one seamless 3D volume, which was used to segment & proofread neurons and synapses. @hhmijanelia.bsky.social

www.biorxiv.org/content/10.1...
October 11, 2025 at 1:30 PM
Reposted by Mike Ando
Happy #FluorescenceFriday! Our #CellLineOfTheWeek is Nucleoporin Nup153! 🧫

Our stem cell lines and plasmids, illuminating specific cell structures, are available for just the cost of shipping to support scientific discovery.

📦 Distributed by @coriellinstitute.bsky.social & @addgene.bsky.social
October 10, 2025 at 9:52 PM
Reposted by Mike Ando
For #FluorescenceFriday, α-spectrin (red) and lipid droplets (green) are shown in adipocytes 🔬 #Microscopy #CellBiology
October 10, 2025 at 6:37 PM
Reposted by Mike Ando
After many years of hm-ing and haw-ing about why some of the fusion proteins I’ve cloned showed cytoplasmic background I’ve finally found the culprit
October 10, 2025 at 7:51 AM
Reposted by Mike Ando
Happy #FluorescenceFriday! This is a maximum intensity projection of depth shaded actin (🌈) in a section from an E9.5 🐭 neural tube (NT). 🔬 by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪 Image shows the floor plate and lumen of the developing NT.

#SciArt #DevBio #DevNeuro
October 10, 2025 at 3:19 PM
Reposted by Mike Ando
🎃💀Boys & girls of every age. Wouldn't you like to see something strange?💀🎃
🖌️🎨I painted Jack Skellington with E. coli expressing the small Ultra-Red Fluorescent Protein (smURFP).🧬🦠🧫
#TheNightmareBeforeChristmas #JackSkellington #SciArt #AgarArt #SciComm
October 10, 2025 at 1:21 PM
Reposted by Mike Ando
Keynote at #COLM2025: Nicholas Carlini from Anthropic

"Are language models worth it?"

Explains that the prior decade of his work on adversarial images, while it taught us a lot, isn't very applied; it's unlikely anyone is actually altering images of cats in scary ways.
October 9, 2025 at 1:12 PM
Reposted by Mike Ando
Now that I can say it publicly - huge congratulations to @michelleitano.bsky.social , winner of this year's @bioimagingna.bsky.social Michael W Davidson award for "Community contributions, in any of the areas of Engagement, Education, Mentorship, and Standardization". So well deserved! #GBIxBINA2025
October 9, 2025 at 3:09 PM