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Reposted by Aida Rodrigo

Sally Lowell @cellysally.bsky.social · 8d

Hot off the press!

Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4

www.nature.com/articles/s41...

Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 - Nature Communications

Here they perform a systematic dissection of OCT4 and reveal how intrinsically disordered regions can be used to serve specific functions during reprogramming and embryonic development. This can be exploited to engineer more efficient and specific reprogramming factors.

www.nature.com

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Aida Rodrigo @aidarodrigo.bsky.social · 13d

Stunning! Congrats, James and team!

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Glover lab @glover-lab.bsky.social · 13d

🚨 Excited to introduce FuChi (Fucci chicken), the first avian cell cycle reporter line. Thank you to all those who contributed to putting this paper together. I really think it showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬 @roslininstitute.bsky.social

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Aida Rodrigo @aidarodrigo.bsky.social · 19d

Go @lizihegarty.bsky.social! 🎉

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Josh Currie @joshcurrie.bsky.social · 20d

💥OUR LAB IS HIRING!!💥

We are hiring a research assistant/lab manager to assist with managing our axolotl colony and enabling some kick-ass science! Looking for high levels of organization, collaboration, problem solving and curiosity.

Application link: tinyurl.com/3tpvphpm
#SciJob #JobAlert

One of your future coworkers in the Currie Lab, an adorable axolotl.

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Elaine Emmerson @doctoremmerson.bsky.social · 22d

#EMDS2025 attendees - if anyone is looking for a postdoc position and likes what they see of #Edinburgh, please come and speak to me or @lizihegarty.bsky.social (poster 71) or @erinwatson.bsky.social (poster 35).

Elaine Emmerson @doctoremmerson.bsky.social · 26d

I am advertising for a #postdoc for a 3 year BBSRC-funded project exploring the role of macrophages in salivary gland development. The successful candidate will be based at @edinuni-irr.bsky.social at @uni-of-edinburgh.bsky.social. Closing date: 9th Oct. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Postdoctoral Research Fellow

An exciting opportunity has arisen to join the Emmerson lab within the Institute for Regeneration and Repair at the University of Edinburgh. This three year, BBSRC-funded postdoctoral research associa...

elxw.fa.em3.oraclecloud.com

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Development @dev-journal.bsky.social · 23d

The Company of Biologists and the British Society for Developmental Biology: a model partnership

As part of the #biologists100 anniversary, Saanjbati Adhikari and Raman Das review the relationship between @biologists.bsky.social and @bsdb.bsky.social

doi.org/10.1242/dev....

An image of two BSDB supplement covers from Journal of Experimental Embryology and Morphology.

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Sally Lowell @cellysally.bsky.social · Sep 7

Thirst for knowledge?

The 2025 Stem Cell Summer School starts next Friday! We have an uncommonly spectacular array of faculty, and have no doubt that our delegates will also be spectacular

Follow ‪@stemcellsummer.bsky.social‬ and #SCSS2025 for updates during the meeting

Stem Cell Summer School @stemcellsummer.bsky.social · Apr 7

The 2025 European Summer School in Stem Cell Biology and Regenerative Medicine will take place 12-19 Sept 2025, on the beautiful Greek island of Spetses.

Keep an eye on our website www.stemcellsummerschool.org for updates, or give us a follow 😀

Deadline for applications: 30th May 2025

Poster listing the faculty for the 2025 stem cell summer school on Spetses. Check our website (URL in bio) for full details.

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Adrian Liston @labliston.bsky.social · Sep 3

🧵How to write and manage your first research budgets

The point of funding is to convert it into quality research. A well-spent research budget should fund the idea it was raised on, plus revision experiments, plus preliminary data for the next grant. So you need to spend, while avoiding waste.

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School of Biological Sciences @cambridgebiosci.bsky.social · Sep 4

New article out now!

Our researchers @sumrubayin.bsky.social, @bensteventon.bsky.social, and @storerlab.bsky.social share key takeaways from a workshop on complex tissue regeneration, highlighting the need for more collaboration and interdisciplinary work.

➡️ journals.biologists.com/dev/article/...

Building and rebuilding complex tissues: strategic visions from a research-led workshop

ABSTRACT. How complex tissues develop and regenerate post-injury is one of the most fascinating and important processes in biology. Recent technical advances that enable the generation of a quantitati...

journals.biologists.com

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Aida Rodrigo @aidarodrigo.bsky.social · Sep 4

Of course you did it! Massive congratulations, Anna! No doubt you will make the most of it!

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Aida Rodrigo @aidarodrigo.bsky.social · Sep 4

HUGE congratulations, Can! Just amazing!

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Anna Williams @annawilliamslab.bsky.social · Aug 31

Our new paper on metformin, myelin, mitochondria and metabolism is now out at rdcu.be/eDbFD
Thanks to Nina and all of the team!

Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function

Nature Communications - Metformin is under clinical trial for brain neuroprotection but how it may work is poorly understood. Here, the authors show that metformin helps myelin formation by human...

rdcu.be

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MDI Biological Laboratory @mdibiolab.bsky.social · Aug 22

MDI Bio Lab has been awarded a 5-year, $2.3M grant from the NIH to train the next generation of leaders in #regenerativemedicine.

The PI for the grant? @murawalalab.bsky.social 👏

#standwithscience #researchmatters 🧪 🤝

NIH Awards MDI Bio Lab $2.3M to Train Leaders in Regenerative Biology

mdibl.org

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Umut Kilik @umut-kilik.bsky.social · Jul 24

🚨 After 7 years in the making, my PhD thesis work is finally published in @science.org 🧬✨
What does our gut say about how we became human? During my hitchhiking journey spanning 3 countries and multiple lab moves

Camp Lab @graycamplab.bsky.social · Jul 24

Diet/microbes place the gut epithelium as a nexus for evolutionary change. With Jason Spence and Craig Lowe labs we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @science.org #evodevo www.science.org/doi/10.1126/... 1/11

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gserranonajera.bsky.social @gserranonajera.bsky.social · Aug 7

Hi bsky!

Do embryonic tissues have backup plans🔀? Gastruloids (model of body elongation) can build an axis through different cellular mechanisms when on adherent substrates instead of free floating. A case of developmental plasticity!

w/ A. Delahaye & ‪@bensteventon.bsky.social‬

shorturl.at/v01DO

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Aida Rodrigo @aidarodrigo.bsky.social · Jul 24

Such great news, Josh! Congratulations! 🎉

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PLOS Biology @plosbiology.org · Jul 16

Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu

Patterning of cell identities in the posterior E8.5 mouse embryo. Co-expression of mesoderm marker TBXT (blue) and neural marker SOX2 (green) identifies cells in the neuromesodermal (NMP) progenitor region at the intersection of their respective gene expression gradients. TBX6 (red) marks paraxial mesoderm and also marks sporadic mesoderm-committed cells emerging within the NMP region. LAMINB1 (white) marks the nuclear envelope of all cells. Credit: Matthew French.

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Mill_lab @cilialab.bsky.social · Jul 7

📣 Cilia Lab is growing 📣 - we have 2️⃣ open positions at @uoe-igc.bsky.social @edinburgh-uni.bsky.social for talented and motivated researchers interested in disease modelling & genetic therapies which target #RareRespiratoryDiseases at their root cause. 🧪🧪#ciliopathies #PrimaryCiliaryDyskinesia 1/4

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Vicki Metzis @vmetzis.bsky.social · Jul 14

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc!

Multiple positions across multiple groups @mrc-lms.bsky.social

Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇

lms.mrc.ac.uk/work/vacanci...

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences

Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

lms.mrc.ac.uk

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Mark Peifer (He, him) @peiferlabunc.bsky.social · Jul 14

Publishing scientific papers is an obstacle course. There are many aspects to this but lengthy review times are one. That's why I am very excited about the new initiative @biologyopen.bsky.social, @biologists.bsky.social open access journal: Fast & Fair 1/n 🧪
journals.biologists.com/bio/pages/fa...

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Vicki Metzis @vmetzis.bsky.social · Jun 27

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

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Rob Illingworth @illingworth-lab.bsky.social · Jul 12

Excited to share our hot-off-the-press @biorxivpreprint.bsky.social
that explores how PRC1-mediated H2AK119ub deposition safeguards lineage fidelity during forebrain development. Fantastic work by @lucyadoyle.bsky.social and our colleagues & collaborators. 🥳🧬🧠🔬
www.biorxiv.org/content/10.1...

H2AK119ub Safeguards Against Ectopic Transcription Factor Mediated Gene Activation in the Developing Forebrain

The PRC1 complex regulates developmental gene expression in mammals by ubiquitinating histones (H2AK119ub) and nucleating repressive chromatin interactions. Human genetic data and functional experimen...

www.biorxiv.org

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Fiona Doetsch @doetschlab.bsky.social · Jul 7

Excited to share our latest on adult neural stem cells & OPCs #GLIA2025 @gliameeting.bsky.social
Stop by our posters!
T15-005A Ana Delgado (Tuesday) Intraventricular OPCs and macrophages/microglia
T15-023C Hanae Omiya (Thursday) Epigenetic/transcriptomic heterogeneity of adult neural stem cells

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Filipa Simões @simoesfilipa.bsky.social · Jul 7

🧪 Job alert 🔊 we are hiring a Research Assistant - join the Simões Group at DPAG-IDRM @ox.ac.uk supporting #cardiovascular development and regeneration research, working with #zebrafish and #human stem cell systems: my.corehr.com/pls/uoxrecru... @oxforddpag.bsky.social @idrm.ox.ac.uk (1/4)

Job Details

my.corehr.com

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