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International Society of Developmental Biology

@isdb.bsky.social

1.8K followers 520 following 39 posts

ISDB is a non-profit scientific association that promotes the study of developmental biology

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International Society of Developmental Biology @isdb.bsky.social · Nov 15

Hello my lovely developmental biologists, The International Society for Developmental Biology is here with y'all in this #BlueSky. If you follow us on Twitter (we refuse to call it X), please drop us a follow here! Let's connect! #DevelopmentalBiology #cellbiology

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Journal of Cell Science @jcellsci.bsky.social · 5d

Mario Ledesma-Terrón, Diego Pérez-Dones, David Míguez and colleagues @cbm-csic-uam.bsky.social @ifimacuam.bsky.social present OSCAR, a framework to quantify 3D stacks with high cellular density.
journals.biologists.com/jcs/article-...

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Eric Peterman @errricpeterman.bsky.social · 5d

cover image yeeeeeeeeehawwwww #flourescentfriday
check out our work in the most recent issue of @jcellsci.bsky.social !

Cover: Skin-resident macrophages (white) migrate towards a scratch wound (centre) in a zebrafish skin explant. To reach the wound margin, migrating macrophages must navigate through a dense network of epithelial cells, which are visualised using a reporter for epithelial junctions (α-catenin-Citrine, magenta). Live-cell imaging and chemical perturbations demonstrate that skin macrophages require microtubules to efficiently respond to tissue damage and navigate epithelial obstacles. See article by E. Peterman et al. (jcs264101).

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Alfonso Martinez Arias @amartinezarias.bsky.social · 5d

Organizing time past, remembered this summary of many thoughts that I continue to pursue
And nowhere rings more true that ‘the detail of pattern is the movement’ than in the actions of cells as they build #embryos
www.youtube.com/watch?v=bbQV...
#CellsRUs #MasterBuilder

Landscapes and embryos : A film from A. Martinez Arias

YouTube video by Cambridge University

www.youtube.com

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Rachael Ott @rachaelott.bsky.social · 5d

For #FluorescenceFriday, RhoA (blue) and the actin cytoskeleton (magenta) are shown in a set of primary microglia 🔬 #Neuroscience #Microscopy

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Marco A. Maximo Prado @maximoprado.bsky.social · 5d

Great collaborative effort to get this done

The MIND Platform @ Western @mind-western.bsky.social · 5d

#fluorescencefriday special. Half marmoset 🧠 cleared and stained using SHIELD and imaged by lightsheet microscopy. Courtesy of Jesleen Saini @shahrzadbahrampour.bsky.social and @stefan-everling.bsky.social

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Maik Bischoff @maikbischoff.bsky.social · 5d

My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls

Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨

🔗 www.nikonsmallworld.com/galleries/20...

#NikonSmallWorld #Microscopy #ScienceArt

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Michalis Averof @michalis-averof.bsky.social · 5d

Here it is! Postdoctoral position to identify the progenitors sensory organs in the regenerating legs of Parhyale

apply here: www.averof-lab.org/pages/tracman

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Michalis Averof @michalis-averof.bsky.social · Jul 13

We've just been awarded a grant to study the cellular basis of regeneration – to track the progenitors of sensory organs in the context of leg regeneration, in our favourite crustacean tinyurl.com/parhyale, based on live imaging and cell tracking. The project involves some cool collaborations... 1/3

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Cells & Development @cellsdev.bsky.social · 5d

We often talk about what signals does the organiser release. But have you ever stopped and asked what does it mean to be the organiser? What cells make up the organiser? Where do they go? What do they do?
Well this review by Claudio Stern may give you the answers:
doi.org/10.1016/j.cd...

Cell movements around the organizer/node after stage HH4.

Fate maps of the ectodermal (dorsal) layer of the organizer/node, based on Selleck and Stern (1991) (Selleck and Stern, 1991).

Cell movements of populations contributing to the organizer.

Stages of early chick development referred to in the text. The diagrams show some of the features used to classify the stages in relation to primitive streak formation.

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International Society of Developmental Biology @isdb.bsky.social · 5d

This looks like a fantastic workshop!

Centro Andaluz de Biología del Desarrollo @cabd-upo-csic.bsky.social · 7d

Amazing @embo.org workshop coming up!!! Are you interested in #MZT? Get to know the program and the deadlines!

🗣️ outstanding group of speakers
📍 amazing city of #Sevilla
🗓️ May 4-7th, 2026

Organized by Miguel A. Moreno-Mateos from #CABD
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Moreno-Mateos Lab @crisprscan.bsky.social · 8d

Glad to share that the website for the MZT EMBO workshop that I organize together with Ana Boskovic (EMBL, Rome), Antonio Giraldez (Yale U) and Melissa Harrison (U Wisconsin) is out: meetings.embo.org/event/26-awa...
Please spread the word and join us in beautiful Seville next 4-7 May!

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Lori O'Brien @llobrienlab.bsky.social · 12d

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

Image of a fluorescently labeled adult mouse kidney showing AQP2 staining of collecting ducts and connecting segment in green and alpha SMA staining of the arterial tree in magenta. The collecting ducts look like squiggly branches.

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Dan Jagger @auditorynerves.bsky.social · 13d

‘Shake it off’: Taylor Swift’s changing voice shows how our accents evolve.

Researchers have confirmed what Taylor Swift fans have long suspected: the music megastar’s dialect & pitch have shifted throughout her career.

🧪👄📣
www.nature.com/articles/d41...

‘Shake it off’: Taylor Swift’s changing voice shows how our accents evolve

An analysis of Swift’s interviews suggests her speech pattern has changed over her career.

www.nature.com

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Development @dev-journal.bsky.social · 12d

Transitions in development – an interview with Mijo Šimunović
We caught up with Mijo Šimunović from @columbiauniversity.bsky.social to learn more about Mijo's transition to becoming a group leader and Mijo's insights on the growing need for cross-disciplinary research: doi.org/10.1242/dev....

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Edouard Hannezo @ehannezo.bsky.social · 12d

Now out in final published form - with a new title "Mechanical control of cell fate decisions in the skin epidermis" and simulations/quantifications! See below for thread of how unbalanced tensions can bias fate choices in minimal 3D models of tissues! www.nature.com/articles/s41...

Edouard Hannezo @ehannezo.bsky.social · Dec 17

Happy to share the latest work from Preeti Sahu, with Adriana Sanchez-Danes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! See 🧵 below (1/n) bit.ly/3ZXxJzk

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Cells & Development @cellsdev.bsky.social · 12d

In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. They found that AP elongation dynamics is size-dependent! Check it out here:
doi.org/10.1016/j.cd...

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Cells & Development @cellsdev.bsky.social · 26d

Our September issue cover is now online.
You can check out the issue here:
www.sciencedirect.com/journal/cell...

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Ryan Savill @cryaaa.bsky.social · 26d

(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...

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Cells & Development @cellsdev.bsky.social · 26d

Epithelial-to-mesenchymal transition or EMT is an integral part of development in animals. In this beautifully illustrated review from the lab of Magali Suzanne, they describe and compare and contrast the cellular mechanism of EMT across the different model organisms.
doi.org/10.1016/j.cd...

Fig. 1. EMT dynamics in developmental models.

Fig. 2. A hypothetical model of EMT dynamics.

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International Society of Developmental Biology @isdb.bsky.social · 26d

This is the cutest thing I've seen all day or year!!!

Chise @sailorrooscout.bsky.social · 26d

Oh to be a little Tardigrade scratching its back on a bubble. 🫧🐻🧪

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Chise @sailorrooscout.bsky.social · 26d

Oh to be a little Tardigrade scratching its back on a bubble. 🫧🐻🧪

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Roberto Mayor Lab @mayorlab.bsky.social · 28d

Early Career Opportunity
Mentorship & career development, access to world-class facilities, and a collaborative, supportive environment. We are particularly interested in researchers in Synthetic Dev. Biol. Mechanobiology and AI . #AcademicJobs #EarlyCareerResearcher #UCL #DevelopmentalBiology

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V4SDB @v4sdb.bsky.social · Sep 6

And here is Gage Crump @crumplab.bsky.social, all the way from @usc.edu, to tell us about Cross-Species Single-Cell Approaches to Facial Development and Evolution. A big thanks to @isdb.bsky.social @cellsdev.bsky.social @devdynamics.bsky.social for sponsoring the talk!
#V4SDB2025 #evodevo

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Cells & Development @cellsdev.bsky.social · Sep 5

For decades, living embryos were the favourite tool to study development. However, their complexity hindered precise dissection of many processes. This comprehensive review provides a comparison between embryos and the power of gastruloids, opening up a new wave of dev bio.
doi.org/10.1016/j.cd...

Fig. 1. Schematic overview of mouse gastrulation

Fig. 4. Different aspects of computational modelling of gastrulation.

Fig. 3. Protein localisation, cell sorting behaviours and signalling pathway activation in gastruloids. Depicted are schematic representations based on integration of existing, fragmented data. Note that there is considerable variation in gastruloid development and existing data quality and resolution, and these cartoons represent our interpretation of average domains of immunofluorescence staining.

Fig. 2. Schematic overview of signalling induced GRNs during gastrulation.

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International Society of Developmental Biology @isdb.bsky.social · Aug 29

A cryosection from an embryo stained for the neural crest (🟠) using HCR, and DAPI (⚪).
Can you guess what embryo this is?
#FluorescenceFriday
Image credit: Ines Fernandez Mosquera, PhD student at @ucl.ac.uk

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Nicolas Chiaruttini @nkiaru.bsky.social · Aug 29

Nice cell division observed on Zeiss LLS7 yesterday! Sample: @romainguiet.bsky.social

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The Company of Biologists @biologists.bsky.social · Aug 29

Our next extraordinary biologist is Jeroen Dobbelaere, a member of the @biologists.bsky.social Sustainability Committee and an early advisor on the event carbon calculator and The Forest of Biologists. #100biologists

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