Lightnews — Scholar-powered news

Reichow Lab

@reichowlab.bsky.social

1.1K followers 540 following 34 posts

Steve Reichow (PI), Laboratory of Biomolecular #CryoEM at Oregon Health & Science University (OHSU) and Pacific Northwest Cryo-EM Center (PNCC) ❄🔬 https://www.reichowlab.com/

www.reichowlab.com

Posts Media Videos Starter Packs

Pinned

Reichow Lab @reichowlab.bsky.social · Feb 21

#NIHFundedDiscovery

How do cells avoid the "kiss of death"?

Gap junctions share life-saving signals—but under stress, they shut down to prevent spreading cytotoxic damage.

#CryoEM reveals the molecular switches behind this process!

www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1...

2 23 140

Reposted by Reichow Lab

Edward T Eng @edwardteng.bsky.social · 4d

Muyuan Chen has turned structural biology into an immersive experience with his new video game Meowtabolism, now available on Steam.
Try the demo here: store.steampowered.com/app/4045010/...
Give Muyuan feedback: steamcommunity.com/app/4045010
#ScienceGaming #StructuralBiology #CryoEM #STEMOutreach

1 24 47

Reposted by Reichow Lab

Institute for Protein Innovation @ipiproteins.bsky.social · 15d

Frequent user of epitope tags? Try ours!

IPI epitope tag antibodies & plasmids are now available through our partner @addgene.bsky.social!

buff.ly/YEuZDIp

Epitope tag antibody collection

Epitope tags are short amino acid sequences fused to a protein’s N- or C-terminus. When paired with an antibody that specifically recognizes this sequence, epit

buff.ly

10 25

Reposted by Reichow Lab

Pacific Northwest Cryo-EM Center (PNCC) @pacificnwcryoem.bsky.social · 15d

#Training 👨‍🏫 🧑‍🏫
#CryoEM ❄️ 🔬
#Science 🧬 🦠
#Education 📚

Huge shoutout to our SPoCs for making this a grand success! 👏
Marzia Miletto
Marcelo Alexandre de Farias
Omar Davulcu

2 3

Reposted by Reichow Lab

Guenter Resch @nexperion.net · 15d

Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit
www.nexperion.net/semcm2026

22 49

Reposted by Reichow Lab

Edward T Eng @edwardteng.bsky.social · 16d

Join us for the next CryoEM Current Practices Webinar on 9/25/2025 at 12 PM ET / 9 AM PT with Dr. Sarah Clark who will sharing her research on the "Architecture of a Bridge-like Lipid Transfer Protein."

Register here:
us02web.zoom.us/webinar/regi...

6 14

Reposted by Reichow Lab

Aaron Reichlin-Melnick @reichlinmelnick.bsky.social · 18d

NEW: Hours before a new entry ban is supposed to go into effect, the federal government officially acknowledges for the first time that the restrictions do NOT apply to people who currently have H-1B visas.

Link: www.uscis.gov/sites/defaul...

J.S. Citizenshit and Immigratior
Services
September 20, 2025
Memorandum
TO:
Associate Directors,
Deputy Associate Directors, Program Office Chiefs
FROM:
JOSEPH B
Digitaly signed by
JOSEPH B EDLOW
Joseph B. Edlow
EDLOW
Date: 2025.09.20
Director, United States Citizenship and Immigration Services **00
SUBJECT: Proclamation, Restriction on Entry of Certain Nonimmigrant Workers, H-IB
On September 19, 2025, the President issued a Proclamation, Restriction on Entry of Certain Nonimmigrant Workers, to address systemic abuse of H-1B nonimmigrant visas. Pursuant to sections 212(f) and 215(a) of the Immigration and Nationality Act (INA), 8 U.S.C. 1182(f) and 1185(a), the entry into the United States of aliens as nonimmigrants to perform services in a specialty occupation under section 101(a)(15)(H)(i)(b) of the INA, 8 U.S.C.
1101(a)(15)(H)(i)(b), is restricted, except for those aliens whose petitions are accompanied or supplemented by a payment of $100,000. This guidance applies to H-IB employment-based petitions filed after 12:01 AM ET on September 21, 2025.|
This proclamation only applies prospectively to petitions that have not yet been filed. The proclamation does not apply to aliens who: are the beneficiaries of petitions that were filed prior to the effective date of the proclamation, are the beneficiaries of currently approved petitions, or are in possession of validly issued H-1B non-immigrant visas. All officers of United States Citizenship and Immigration Services shall ensure that their decisions are consistent with this guidance. The proclamation does not impact the ability of any current visa holder to travel to or rom the United States.
cc: David V. Roy, Chief Counsel (A)
FOUO, For Official Use Only

170 1K 2.7K

Reichow Lab @reichowlab.bsky.social · 23d

Congrats, again, Steve and team!

1 1

Reposted by Reichow Lab

mansoorlabohsu.bsky.social @mansoorlabohsu.bsky.social · 23d

Another manuscript from our group this week with the first structures of the human P2X7 receptor facilitating development of a novel scaffold for P2X7R antagonists:

urldefense.com/v3/__https:/...

@pacificnwcryoem.bsky.social
@ohsunews.bsky.social
@ohsubrain.bsky.social

1 4 9

Reposted by Reichow Lab

mansoorlabohsu.bsky.social @mansoorlabohsu.bsky.social · 25d

Our latest work on the human P2X2 receptor. We identified an alternate desensitized state conformation that provides insight into how ATP enters and/or leaves the pocket.

www.pnas.org/doi/10.1073/...

@pacificnwcryoem.bsky.social
@ohsunews.bsky.social
@ohsubrain.bsky.social

1 7

Reposted by Reichow Lab

Dr. Wendy Bohon @drwendyrocks.bsky.social · Sep 6

👏👏👏 👏👏

6 180 450

Reichow Lab @reichowlab.bsky.social · Aug 30

What a fun story, congrats to the team on their beautiful work!

Reposted by Reichow Lab

Oli Clarke @olibclarke.bsky.social · Aug 30

Happy to share a new preprint from the Clarke & Vallese (@fravallese.bsky.social) labs reporting #cryoem structures of two RBC stomatin complexes – with AQP1 & UT-B - continuing the SPFH theme from our recent vault preprint! This was a fun one and has been cooking for a while - read on for more! ⬇️

Upper - cryo-EM reconstruction of stomatin AQP1 complex. Lower - reconstruction of stomatin-UT-B complex.

8 30 120

Reposted by Reichow Lab

Jonathan Pruneda @jnpruneda.bsky.social · Aug 26

Come be my boss! We’re looking for a passionate and supportive leader for our Department of Molecular Microbiology and Immunology. Research in MMI spans diverse models and systems of host-pathogen interactions. Come join us in the beautiful Pacific NW!

facultycareers-ohsu.icims.com/jobs/35624/c...

Faculty Portal | OHSU

facultycareers-ohsu.icims.com

2 23 32

Reposted by Reichow Lab

Kihara Laboratory @kiharalab.bsky.social · Aug 20

PNCC Cryo-EM modeling and validation workshop on Sep 3-5, 2025. Register now! tinyurl.com/Cryo-EMModel...

2 3

Reposted by Reichow Lab

Danielle Grotjahn @nanigrotjahn.bsky.social · Aug 20

🚨 #teamtomo!🚨
Did you know there's a dedicated cryoEM/ET Mini-Symposium at the upcoming ASCB/EMBO meeting in Philly (Dec 6–10)??

2 4 10

Reichow Lab @reichowlab.bsky.social · Aug 19

Congratulations!

Reposted by Reichow Lab

Edward T Eng @edwardteng.bsky.social · Jul 29

If you are at #MM2025 come by booth 1135 to learn more about the NIH sponsored transformative high resolution #cryoEM & #cryoET programs. We offer these technologies to the nation at no cost at the point of access.

cryoemcenters.org cryoetportal.org

3 9

Reposted by Reichow Lab

BWJones @bwjones.bsky.social · Jul 28

Wes Sundquist is one of the good guys. He is a scientists scientist and has carefully, passionately, and consistently carried his science out with this goal in mind. A cure for AIDS that is available to all.

This is an amazing recognition for him and for the @utah.edu where he has done his work.

eric gonzalez juenke @egojunk.bsky.social · Jul 28

Normalize talking about fed. $ when these headlines happen. Thousands of scientists, working for decades funded by the federal government did this. At times, people thought this was useless research. Below is some info about the HIV labs at the University of Utah. 🧵 www.science.org/doi/10.1126/...

2 15 45

Reposted by Reichow Lab

CCeMMP Outreach @ccemmp-outreach.bsky.social · Jul 26

Less than 2 weeks to go! 🤯Mare sure you prepare your entries for our 2nd @arc_gov_au CCeMMP 'Bench to Art' Exhibition during National Science Week & win cash prizes 💰! Please like & share 👍 More info: ccemmp.org/events/arc-c...
#CryoEM
#CryoET
#MembraneProtein
#GPCR

ARC CCeMMP 2nd Annual Bench to Art Exhibition 2025 | CCeMMP

The Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins (CCeMMP) is holding their 2nd Annual ‘Bench to Art’ Exhibition to showcase the artistic flair of structural bio...

ccemmp.org

5 9

Reposted by Reichow Lab

Edward T Eng @edwardteng.bsky.social · Jul 27

The next #CryoEM Current Practices Webinar speaker will be Puja Majumder from MSKCC speaking on "From Micrographs to Maps: Structural Basis of a Filamentous CRISPR Effector Revealed by Cryo-EM" 7/31/2025 at 12 PM ET / 9AM PT

Sign up today:
us02web.zoom.us/webinar/regi...

3 8

Reposted by Reichow Lab

Jorge E. Contreras @drcontrexin.bsky.social · Jul 23

Exciting news! The EPIC/SGP Symposium at UC Davis will be accompanied by a special issue in the Journal of General Physiology. Stay tuned for more details about this incredible event celebrating cutting-edge research on ion channels!

Journal of General Physiology @jgp.org · Jul 22

📣 #CallForPapers 📣 on the topic of the inaugural in-person Electrophysiology & Ion Channel (EpIC) meeting, “Emerging Research on Ion Channels in Health & Disease” – w/ Guest Editors Jelena Baranovic, Osama Harraz, Conor McClenaghan, & Lejla Zubcevic 👉 rupress.org/JGP/pages/ca...

8 12

Reposted by Reichow Lab

Sarah Piper @sarahjpiper.bsky.social · Jul 15

Big news indeed 👏 make sure you check out the post&link below 🤩
#cryoEM #cryoET
#membraneproteins #GPCRs #scivis #scicomm

CCeMMP Outreach @ccemmp-outreach.bsky.social · Jul 15

Big news! 📢CCeMMP is holding the 2nd 'Bench to Art' Exhibition to showcase the artistic flair of structural biology. Share your creations to be displayed in a virtual gallery during National Science Week & for a chance to win cash prizes 💰! More info: ccemmp.org/events/arc-c...

#CryoEM
#Membranes

4 10

Reposted by Reichow Lab

Pacific Northwest Cryo-EM Center (PNCC) @pacificnwcryoem.bsky.social · Jul 15

Apply here www.pairupscience.org/cryo-em-work...

1 1

Reposted by Reichow Lab

Danielle Grotjahn @nanigrotjahn.bsky.social · Jul 11

I have lots of opinions—but for your sake, I’ve limited them to segmentation in cryo-ET for this article 😉
www.sciencedirect.com/science/arti...

#teamtomo

Segmenting cryo-electron tomography data: Extracting models from cellular landscapes

Cryo-electron tomography provides an unprecedented view of cellular architecture, yet extracting meaningful biological insights remains challenging. S…

www.sciencedirect.com

1 11 37

Reichow Lab @reichowlab.bsky.social · Jul 9

Beautiful work! 🤩 Great to see cryo-EM and cryo-ET continuing to shine new light on gap junction biology!