Mart Krupovìč | Lightnews

BejaLab @bejalab.bsky.social · 23h

Arbitrium systems control lysis/lysogeny through the regulation of small antirepressor proteins www.biorxiv.org/content/10.1...

Satoshi Kawato 川戸智 @kawatosatoshi.bsky.social · 1d

New update for the gbdraw web app!🚀
You can now display gene labels ONLY on the first genome in the linear diagram. Just select "First" in the "Label layout" option.
Try it out here👉: gbdraw.streamlit.app
#gbdraw #bioinformatics #genomics #visualization #virology #microbiology #streamlit

Christophe Zimmer @chzimmer.bsky.social · 2d

Recently out: “Uniform dynamics of cohesin-mediated loop extrusion in living human cells”. In this study led by brilliant former PhD student Thomas Sabaté we use live cell microscopy and polymer simulations to characterize how DNA loops and TADs form in human cells by cohesin-driven extrusion. (1/4)

Alexander Harms @aharms485.bsky.social · 5d

🚨Preprint alert - this is a big one! We transfer the revolutionary power of TnSeq to bacteriophages.

Our HIDEN-SEQ links the "dark matter" genes of your favorite phage to any selectable phenotype, guiding the path from fun observations to molecular mechanisms.

A thread 1/8

Daniela Barillà @danielabarilla.bsky.social · 5d

Let’s wrap things up: my commentary on the Asgard hypernucleosomes.

Congratulations to all the authors of the paper 🍾!

kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Cryo-EM reveals open and closed Asgard chromatin assemblies: Molecular Cell www.cell.com/molecular-ce...

Cryo-EM reveals open and closed Asgard chromatin assemblies

Ranawat et al. show the cryo-EM structures of Asgard archaeal chromatin assemblies, revealing that the histone HHoB assembles into both compact closed and extended open hypernucleosomes. The closed co...

www.cell.com

roop-dhillon.bsky.social @roop-dhillon.bsky.social · 8d

New video on Nested Symbiosis in extreme environments out on my YouTube Channel. Give it a watch if you can, a great paper by @mkrupovic.bsky.social

Original Paper: doi.org/10.1038/s415...

youtu.be/OQR5obtf7-4

Nested Symbiosis in Extreme Environments

YouTube video by Archaeal Adventures

youtu.be

Rubén González @rubengonzalez.bsky.social · 10d

Version 2 is out! More comprehensive text plus new tissue- and pathway-specific analysis revealing how different viruses trigger systemic aging through diverse mechanisms.
www.biorxiv.org/content/10.1...

Vivek Mutalik @vivekmutalik.bsky.social · 10d

Amazing piece of work from @rtoshiro.bsky.social
& Kim Seed at UC Berkeley. 🙌
Played a tiny role in this work.

Surviving phage attack dynamically regulates bacterial immunity to defeat counterdefenses

www.biorxiv.org/content/10.1...

bsky.app

Mart Krupovic @mkrupovic.bsky.social · 10d

Welcome to @pasteur.fr , Spyros! It will be great to have you!

Karim Majzoub @karimaj.bsky.social · 11d

My lab is recruiting a post-doc ! please share ! emploi.cnrs.fr/Offres/CDD/U...

Mart Krupovic @mkrupovic.bsky.social · 12d

Thanks Karim.

Yann Moalic @drym.bsky.social · 13d

www.nature.com/articles/s41...

Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology

An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...

www.nature.com

BejaLab @bejalab.bsky.social · 13d

Viral NblA proteins negatively affect oceanic cyanobacterial photosynthesis www.nature.com/articles/s41...
this project was led by @omernadel.bsky.social and is a joint work between the labs of @bejalab.bsky.social, Debbie Lindell and Oded Kleifeld from @biologytechnion.bsky.social

the sun is shining through the clouds in the sky above the ocean

ALT: the sun is shining through the clouds in the sky above the ocean

media.tenor.com

Sorek Lab @soreklab.bsky.social · 19d

Preprint: Bacteria sense virus-induced genome degradation via methylated mononucleotides

tinyurl.com/ch3damp

We show how molecular byproducts released during virus-induced cell exploitation are used as signals to trigger host immunity

Revealed by the amazing Ilya Osterman. See his thread below👇

Fengbin (Jerry) Wang @jerryknowsnothing.bsky.social · 22d

Check out the fancy anti-parallel cytochrome nanowire bundles structure we've solved. This structure originates from a bacterium, strain name WTL (well-to-live), isolated by the Bond group from the Soudan Underground Iron Mine, located 713 m below the surface. www.biorxiv.org/content/10.1...

A Bundled Antiparallel Cytochrome Nanowire Structure Suggests Roles in Cell-Cell Electron Transfer and Biofilm Formation

Long-range extracellular electron transfer enables respiring microbes to use minerals, other organisms, or electrodes as electron acceptors by transporting electrons microns away from the cell surface...

www.biorxiv.org

Romain Villa @romain-villa.bsky.social · 22d

Curious about the top methane-maker in your gut? Meet this month's featured microbe and find out! 🦠💨🔥 in @cp-trendsmicrobiol.bsky.social #archaeasky
@sgribaldo.bsky.social @pasteur.fr
🔗 Full article linked in reply👇
www.sciencedirect.com/science/arti...

Methanobrevibacter smithii

www.sciencedirect.com

DEEMteam_Orsay @deemteam.bsky.social · 23d

This paper has been a must! Great collaboration with @mkrupovic.bsky.social and @yifanzhou.bsky.social, a N&V by a legend of halophilic archaea tinyurl.com/yc3dcv72, and one picture of one of our expeditions to Dallol making the cover of the November issue of @natmicrobiol.nature.com

rdcu.be/eLtCH

Svetlana Dodonova @dodonova-sveta.bsky.social · 28d

Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...

Fengbin (Jerry) Wang @jerryknowsnothing.bsky.social · Oct 24

First time posting on Bluesky! 🥳 We discovered a new pilus family in cyanobacteria. The pilin has a novel protein fold that forms a super-tight double-layer tube. Similar gene clusters exist in a few cyanobacterial orders. A great collaboration with John and others! www.nature.com/articles/s41...

A family of tubular pili from harmful algal bloom forming cyanobacterium Microcystis aeruginosa - Nature Communications

Ricca et al discover a new family of tubular pili in Microcystis aeruginosa, a harmful algal bloom-forming cyanobacterium. These pili are crucial for buoyancy by forming cell micro-colonies, which inc...

www.nature.com

Soil Microbial Ecology Group @soilmicrobes.bsky.social · Oct 21

📣 PhD Scholarship Opportunity for International Students!
Are you looking to do a PhD in soil microbial and viral ecology?
✍️ Get in touch now!!
✅ Requirements: Masters degree, Distinguished CV, Highly motivated
⏳ Application deadline: November 24
www.univ-lyon1.fr/recherche/fo...

APPEL A PROJET

www.univ-lyon1.fr

Fabai Wu @fabaiwu.bsky.social · Oct 21

Glad to share our paper out today @NatureEcoEvo: “Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor”. www.nature.com/articles/s41... #microsky #archaeasky

Serial innovations by Asgard archaea shaped the DNA replication machinery of the early eukaryotic ancestor - Nature Ecology & Evolution

Phylogenetic and biochemical analyses show a diversity of components of the DNA replication machinery in different Asgard archaea that contributed to the eukaryotic DNA replication machinery.

www.nature.com

Nature Microbiology @natmicrobiol.nature.com · Oct 20

Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions

Out now in Nature Microbiology, by Yifan Zhou, Mart Krupovic & colleagues.
@mkrupovic.bsky.social
@yifanzhou.bsky.social
@deemteam.bsky.social

www.nature.com/articles/s41...

Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology

An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...

www.nature.com

Mart Krupovic @mkrupovic.bsky.social · Oct 20

A nice N&V article by Mike Dyall-Smith on our recent paper
( www.nature.com/articles/s41... ):

www.nature.com/articles/s41...

Archaeal symbioses all the way down - Nature Microbiology

Ethiopian salt lakes feature unique microbial communities with nesting layers of symbioses, where haloarchaea and their ultra-small archaeal symbionts are prey to viruses, which are in turn hijacked b...

www.nature.com

Simon Roux @simrouxvirus.bsky.social · Oct 18

Now published: EnVhogDB, a large database of viral protein family HMM profiles to help functional annotation of new phage genomes - peercommunityjournal.org/articles/10....

EnVhogDB: an extended view of the viral protein families on Earth through a vast collection of HMM profiles

peercommunityjournal.org

Mart Krupovic @mkrupovic.bsky.social · Oct 17

Check out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov
Free access link: rdcu.be/eLtCH
🧵 by @yifanzhou.bsky.social 👇

Yifan ZHOU @yifanzhou.bsky.social · Oct 17

Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology!
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...

Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology

An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...

www.nature.com

Yifan ZHOU @yifanzhou.bsky.social · Oct 17

Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology!
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...

Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology

An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...

www.nature.com

Stefan Rothenburg @stefanrothenburg.bsky.social · Oct 16

Now with the correct link:
We reviewed the "Molecular Mechanisms of Poxvirus Evolution"
We show that poxviruses have highly adaptable genomes, and are not sluggishly evolving, as often described.
journals.asm.org/doi/10.1128/...

Jeremy Barr @jeremyjbarr.bsky.social · Oct 15

Very excited to share the latest work from our lab, which was published today in Nature!
nature.com/articles/s41...

PhD graduate and now post-doc Sofia Dahlman, along with co-senior author Sam Forster from The Hudson and other researchers from our lab and others.